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GATA3_ARATH
ID   GATA3_ARATH             Reviewed;         269 AA.
AC   Q8L4M6; O49742; O65690;
DT   26-APR-2005, integrated into UniProtKB/Swiss-Prot.
DT   26-APR-2005, sequence version 2.
DT   03-AUG-2022, entry version 127.
DE   RecName: Full=GATA transcription factor 3;
DE            Short=AtGATA-3;
GN   Name=GATA3; OrderedLocusNames=At4g34680; ORFNames=T4L20.260;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA], FUNCTION, INDUCTION, AND TISSUE SPECIFICITY.
RC   STRAIN=cv. Columbia;
RX   PubMed=12139008; DOI=10.1023/a:1016062325584;
RA   Teakle G.R., Manfield I.W., Graham J.F., Gilmartin P.M.;
RT   "Arabidopsis thaliana GATA factors: organisation, expression and DNA-
RT   binding characteristics.";
RL   Plant Mol. Biol. 50:43-57(2002).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=10617198; DOI=10.1038/47134;
RA   Mayer K.F.X., Schueller C., Wambutt R., Murphy G., Volckaert G., Pohl T.,
RA   Duesterhoeft A., Stiekema W., Entian K.-D., Terryn N., Harris B.,
RA   Ansorge W., Brandt P., Grivell L.A., Rieger M., Weichselgartner M.,
RA   de Simone V., Obermaier B., Mache R., Mueller M., Kreis M., Delseny M.,
RA   Puigdomenech P., Watson M., Schmidtheini T., Reichert B., Portetelle D.,
RA   Perez-Alonso M., Boutry M., Bancroft I., Vos P., Hoheisel J.,
RA   Zimmermann W., Wedler H., Ridley P., Langham S.-A., McCullagh B.,
RA   Bilham L., Robben J., van der Schueren J., Grymonprez B., Chuang Y.-J.,
RA   Vandenbussche F., Braeken M., Weltjens I., Voet M., Bastiaens I., Aert R.,
RA   Defoor E., Weitzenegger T., Bothe G., Ramsperger U., Hilbert H., Braun M.,
RA   Holzer E., Brandt A., Peters S., van Staveren M., Dirkse W., Mooijman P.,
RA   Klein Lankhorst R., Rose M., Hauf J., Koetter P., Berneiser S., Hempel S.,
RA   Feldpausch M., Lamberth S., Van den Daele H., De Keyser A., Buysshaert C.,
RA   Gielen J., Villarroel R., De Clercq R., van Montagu M., Rogers J.,
RA   Cronin A., Quail M.A., Bray-Allen S., Clark L., Doggett J., Hall S.,
RA   Kay M., Lennard N., McLay K., Mayes R., Pettett A., Rajandream M.A.,
RA   Lyne M., Benes V., Rechmann S., Borkova D., Bloecker H., Scharfe M.,
RA   Grimm M., Loehnert T.-H., Dose S., de Haan M., Maarse A.C., Schaefer M.,
RA   Mueller-Auer S., Gabel C., Fuchs M., Fartmann B., Granderath K., Dauner D.,
RA   Herzl A., Neumann S., Argiriou A., Vitale D., Liguori R., Piravandi E.,
RA   Massenet O., Quigley F., Clabauld G., Muendlein A., Felber R., Schnabl S.,
RA   Hiller R., Schmidt W., Lecharny A., Aubourg S., Chefdor F., Cooke R.,
RA   Berger C., Monfort A., Casacuberta E., Gibbons T., Weber N., Vandenbol M.,
RA   Bargues M., Terol J., Torres A., Perez-Perez A., Purnelle B., Bent E.,
RA   Johnson S., Tacon D., Jesse T., Heijnen L., Schwarz S., Scholler P.,
RA   Heber S., Francs P., Bielke C., Frishman D., Haase D., Lemcke K.,
RA   Mewes H.-W., Stocker S., Zaccaria P., Bevan M., Wilson R.K.,
RA   de la Bastide M., Habermann K., Parnell L., Dedhia N., Gnoj L., Schutz K.,
RA   Huang E., Spiegel L., Sekhon M., Murray J., Sheet P., Cordes M.,
RA   Abu-Threideh J., Stoneking T., Kalicki J., Graves T., Harmon G.,
RA   Edwards J., Latreille P., Courtney L., Cloud J., Abbott A., Scott K.,
RA   Johnson D., Minx P., Bentley D., Fulton B., Miller N., Greco T., Kemp K.,
RA   Kramer J., Fulton L., Mardis E., Dante M., Pepin K., Hillier L.W.,
RA   Nelson J., Spieth J., Ryan E., Andrews S., Geisel C., Layman D., Du H.,
RA   Ali J., Berghoff A., Jones K., Drone K., Cotton M., Joshu C., Antonoiu B.,
RA   Zidanic M., Strong C., Sun H., Lamar B., Yordan C., Ma P., Zhong J.,
RA   Preston R., Vil D., Shekher M., Matero A., Shah R., Swaby I.K.,
RA   O'Shaughnessy A., Rodriguez M., Hoffman J., Till S., Granat S., Shohdy N.,
RA   Hasegawa A., Hameed A., Lodhi M., Johnson A., Chen E., Marra M.A.,
RA   Martienssen R., McCombie W.R.;
RT   "Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana.";
RL   Nature 402:769-777(1999).
RN   [3]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=14593172; DOI=10.1126/science.1088305;
RA   Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA   Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA   Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA   Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA   Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA   Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA   Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA   Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA   Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA   Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA   Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA   Ecker J.R.;
RT   "Empirical analysis of transcriptional activity in the Arabidopsis
RT   genome.";
RL   Science 302:842-846(2003).
RN   [5]
RP   GENE FAMILY ORGANIZATION.
RX   PubMed=15084732; DOI=10.1104/pp.103.037788;
RA   Reyes J.C., Muro-Pastor M.I., Florencio F.J.;
RT   "The GATA family of transcription factors in Arabidopsis and rice.";
RL   Plant Physiol. 134:1718-1732(2004).
CC   -!- FUNCTION: Transcriptional activator that specifically binds 5'-GATA-3'
CC       or 5'-GAT-3' motifs within gene promoters. May be involved in the
CC       regulation of some light-responsive genes.
CC       {ECO:0000269|PubMed:12139008}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC   -!- TISSUE SPECIFICITY: Mostly expressed in roots. Also expressed in stems,
CC       flowers and leaves. {ECO:0000269|PubMed:12139008}.
CC   -!- INDUCTION: In leaves, less expressed in dark than in light.
CC       {ECO:0000269|PubMed:12139008}.
CC   -!- SIMILARITY: Belongs to the type IV zinc-finger family. Class A
CC       subfamily. {ECO:0000305}.
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DR   EMBL; Y13650; CAA74001.1; -; mRNA.
DR   EMBL; AL023094; CAA18847.2; -; Genomic_DNA.
DR   EMBL; AL161586; CAB80185.1; -; Genomic_DNA.
DR   EMBL; CP002687; AEE86409.1; -; Genomic_DNA.
DR   EMBL; CP002687; AEE86410.1; -; Genomic_DNA.
DR   EMBL; AY099790; AAM20641.1; -; mRNA.
DR   EMBL; AY128907; AAM91307.1; -; mRNA.
DR   PIR; H85408; H85408.
DR   PIR; T05288; T05288.
DR   RefSeq; NP_001031789.1; NM_001036712.2.
DR   RefSeq; NP_195194.1; NM_119634.4.
DR   AlphaFoldDB; Q8L4M6; -.
DR   SMR; Q8L4M6; -.
DR   BioGRID; 14902; 13.
DR   IntAct; Q8L4M6; 9.
DR   STRING; 3702.AT4G34680.2; -.
DR   PaxDb; Q8L4M6; -.
DR   PRIDE; Q8L4M6; -.
DR   ProteomicsDB; 247358; -.
DR   EnsemblPlants; AT4G34680.1; AT4G34680.1; AT4G34680.
DR   EnsemblPlants; AT4G34680.2; AT4G34680.2; AT4G34680.
DR   GeneID; 829620; -.
DR   Gramene; AT4G34680.1; AT4G34680.1; AT4G34680.
DR   Gramene; AT4G34680.2; AT4G34680.2; AT4G34680.
DR   KEGG; ath:AT4G34680; -.
DR   Araport; AT4G34680; -.
DR   TAIR; locus:2139594; AT4G34680.
DR   eggNOG; KOG1601; Eukaryota.
DR   HOGENOM; CLU_045755_1_1_1; -.
DR   InParanoid; Q8L4M6; -.
DR   OMA; LTQTHKT; -.
DR   OrthoDB; 1535935at2759; -.
DR   PhylomeDB; Q8L4M6; -.
DR   PRO; PR:Q8L4M6; -.
DR   Proteomes; UP000006548; Chromosome 4.
DR   ExpressionAtlas; Q8L4M6; baseline and differential.
DR   Genevisible; Q8L4M6; AT.
DR   GO; GO:0005730; C:nucleolus; HDA:TAIR.
DR   GO; GO:0005634; C:nucleus; HDA:TAIR.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; ISS:TAIR.
DR   GO; GO:0000976; F:transcription cis-regulatory region binding; IPI:TAIR.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0030154; P:cell differentiation; IBA:GO_Central.
DR   GO; GO:0007623; P:circadian rhythm; IEP:TAIR.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IEA:InterPro.
DR   CDD; cd00202; ZnF_GATA; 1.
DR   Gene3D; 3.30.50.10; -; 1.
DR   InterPro; IPR016679; TF_GATA_pln.
DR   InterPro; IPR000679; Znf_GATA.
DR   InterPro; IPR013088; Znf_NHR/GATA.
DR   Pfam; PF00320; GATA; 1.
DR   PIRSF; PIRSF016992; TF_GATA_plant; 1.
DR   SMART; SM00401; ZnF_GATA; 1.
DR   PROSITE; PS00344; GATA_ZN_FINGER_1; 1.
DR   PROSITE; PS50114; GATA_ZN_FINGER_2; 1.
PE   2: Evidence at transcript level;
KW   Activator; DNA-binding; Metal-binding; Nucleus; Reference proteome;
KW   Transcription; Transcription regulation; Zinc; Zinc-finger.
FT   CHAIN           1..269
FT                   /note="GATA transcription factor 3"
FT                   /id="PRO_0000083432"
FT   ZN_FING         176..230
FT                   /note="GATA-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00094"
FT   REGION          245..269
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOTIF           136..143
FT                   /note="Nuclear localization signal"
FT                   /evidence="ECO:0000255"
FT   CONFLICT        35
FT                   /note="R -> Q (in Ref. 4; AAM20641/AAM91307)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   269 AA;  30468 MW;  207D5D9BAE5B5477 CRC64;
     MELWTEARAL KASLRGESTI SLKHHQVIVS EDLSRTSSLP EDFSVECFLD FSEGQKEEEE
     EVVSVSSSQE QEEQEHDCVF SSQPCIFDQL PSLPDEDVEE LEWVSRVVDD CSSPEVSLLL
     TQTHKTKPSF SRIPVKPRTK RSRNSLTGSR VWPLVSTNHQ HAATEQLRKK KQETVLVFQR
     RCSHCGTNNT PQWRTGPVGP KTLCNACGVR FKSGRLCPEY RPADSPTFSN EIHSNLHRKV
     LELRKSKELG EETGEASTKS DPVKFGSKW
 
 
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