ID   ALIB_STRPN              Reviewed;         652 AA.
AC   P0A4G0; Q51933;
DT   15-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT   15-MAR-2005, sequence version 1.
DT   03-AUG-2022, entry version 90.
DE   RecName: Full=Oligopeptide-binding protein AliB;
DE   Flags: Precursor;
GN   Name=aliB; OrderedLocusNames=SP_1527;
OS   Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4).
OC   Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae;
OC   Streptococcus.
OX   NCBI_TaxID=170187;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=R6 / R800;
RX   PubMed=8051706; DOI=10.1006/jmbi.1994.1472;
RA   Alloing G., de Philip P., Claverys J.-P.;
RT   "Three highly homologous membrane-bound lipoproteins participate in
RT   oligopeptide transport by the Ami system of the Gram-positive Streptococcus
RT   pneumoniae.";
RL   J. Mol. Biol. 241:44-58(1994).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-334 / TIGR4;
RX   PubMed=11463916; DOI=10.1126/science.1061217;
RA   Tettelin H., Nelson K.E., Paulsen I.T., Eisen J.A., Read T.D.,
RA   Peterson S.N., Heidelberg J.F., DeBoy R.T., Haft D.H., Dodson R.J.,
RA   Durkin A.S., Gwinn M.L., Kolonay J.F., Nelson W.C., Peterson J.D.,
RA   Umayam L.A., White O., Salzberg S.L., Lewis M.R., Radune D.,
RA   Holtzapple E.K., Khouri H.M., Wolf A.M., Utterback T.R., Hansen C.L.,
RA   McDonald L.A., Feldblyum T.V., Angiuoli S.V., Dickinson T., Hickey E.K.,
RA   Holt I.E., Loftus B.J., Yang F., Smith H.O., Venter J.C., Dougherty B.A.,
RA   Morrison D.A., Hollingshead S.K., Fraser C.M.;
RT   "Complete genome sequence of a virulent isolate of Streptococcus
RT   pneumoniae.";
RL   Science 293:498-506(2001).
CC   -!- FUNCTION: Part of the binding-protein-dependent transport system for
CC       oligopeptides; probably an oligopeptide binding protein.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Lipid-anchor
CC       {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the bacterial solute-binding protein 5 family.
CC       {ECO:0000305}.
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DR   EMBL; Z16082; CAA78896.1; -; Genomic_DNA.
DR   EMBL; AE005672; AAK75616.1; -; Genomic_DNA.
DR   PIR; G95177; G95177.
DR   PIR; S47979; S47979.
DR   RefSeq; WP_000748873.1; NZ_AKVY01000001.1.
DR   AlphaFoldDB; P0A4G0; -.
DR   SMR; P0A4G0; -.
DR   STRING; 170187.SP_1527; -.
DR   PRIDE; P0A4G0; -.
DR   EnsemblBacteria; AAK75616; AAK75616; SP_1527.
DR   GeneID; 60233458; -.
DR   GeneID; 66806619; -.
DR   KEGG; spn:SP_1527; -.
DR   eggNOG; COG4166; Bacteria.
DR   OMA; AQDPYYN; -.
DR   PhylomeDB; P0A4G0; -.
DR   BioCyc; SPNE170187:G1FZB-1546-MON; -.
DR   Proteomes; UP000000585; Chromosome.
DR   GO; GO:0043190; C:ATP-binding cassette (ABC) transporter complex; IEA:InterPro.
DR   GO; GO:0042597; C:periplasmic space; IEA:UniProt.
DR   GO; GO:0015833; P:peptide transport; IEA:UniProtKB-KW.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR   InterPro; IPR030678; Peptide/Ni-bd.
DR   InterPro; IPR039424; SBP_5.
DR   InterPro; IPR023765; SBP_5_CS.
DR   InterPro; IPR000914; SBP_5_dom.
DR   PANTHER; PTHR30290; PTHR30290; 1.
DR   Pfam; PF00496; SBP_bac_5; 1.
DR   PIRSF; PIRSF002741; MppA; 1.
DR   PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
DR   PROSITE; PS01040; SBP_BACTERIAL_5; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Lipoprotein; Membrane; Palmitate; Peptide transport;
KW   Protein transport; Signal; Transport.
FT   SIGNAL          1..24
FT                   /evidence="ECO:0000305"
FT   CHAIN           25..652
FT                   /note="Oligopeptide-binding protein AliB"
FT                   /id="PRO_0000031785"
FT   LIPID           25
FT                   /note="N-palmitoyl cysteine"
FT                   /evidence="ECO:0000305"
FT   LIPID           25
FT                   /note="S-diacylglycerol cysteine"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        55
FT                   /note="A -> R (in Ref. 1; CAA78896)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        79..80
FT                   /note="SL -> HI (in Ref. 1; CAA78896)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        123..124
FT                   /note="LQ -> FE (in Ref. 1; CAA78896)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        501
FT                   /note="G -> E (in Ref. 1; CAA78896)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   652 AA;  72562 MW;  169B67FD78CFF0CF CRC64;
     MKKSKSKYLT LAGLVLGTGV LLSACGNSST ASKTYNYVYS SDPSSLNYLA ENRAATSDIV
     ANLVDGLLEN DQYGNIIPSL AEDWTVSQDG LTYTYKLRKD AKWFTSEGEE YAPVTAQDFV
     TGLQYAADKK SEALYLVQDS VAGLDDYITG KTSDFSTVGV KALDDQTVQY TLVKPELYWN
     SKTLATILFP VNADFLKSKG DDFGKADPSS ILYNGPFLMK ALVSKSAIEY KKNPNYWDAK
     NVFVDDVKLT YYDGSDQESL ERNFTAGAYT TARLFPNSSS YEGIKEKYKN NIIYSMQNST
     SYFFNFNLDR KSYNYTSKTS DIEKKSTQEA VLNKNFRQAI NFAFDRTSYG AQSEGKEGAT
     KILRNLVVPP NFVSIKGKDF GEVVASKMVN YGKEWQGINF ADGQDPYYNP EKAKAKFAEA
     KKELEAKGVQ FPIHLDKTVE VTDKVGIQGV SSIKQSIESV LGSDNVVIDI QQLTSDEFDS
     SGYFAQTAAQ KDYDLYHGGW GPDYQDPSTY LDIFNTNSGG FLQNLGLEPG EANDKAKAVG
     LDVYTQMLEE ANKEQDPAKR YEKYADIQAW LIDSSLVLPS VSRGGTPSLR RTVPFAAAYG
     LTGTKGVESY KYLKVQDKIV TTDEYAKARE KWLKEKEESN KKAQEELAKH VK