ALIS4_ARATH
ID ALIS4_ARATH Reviewed; 336 AA.
AC Q9SA35; F4I2W8; Q682N7;
DT 24-MAR-2009, integrated into UniProtKB/Swiss-Prot.
DT 25-JAN-2012, sequence version 2.
DT 03-AUG-2022, entry version 89.
DE RecName: Full=Putative ALA-interacting subunit 4;
DE Short=AtALIS4;
GN Name=ALIS4; OrderedLocusNames=At1g16360; ORFNames=F3O9.16;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 61-336.
RC STRAIN=cv. Columbia;
RA Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA Shinozaki K.;
RT "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL Submitted (SEP-2004) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP NOMENCLATURE, AND TISSUE SPECIFICITY.
RX PubMed=18344284; DOI=10.1105/tpc.107.054767;
RA Poulsen L.R., Lopez-Marques R.L., McDowell S.C., Okkeri J., Licht D.,
RA Schulz A., Pomorski T., Harper J.F., Palmgren M.G.;
RT "The Arabidopsis P4-ATPase ALA3 localizes to the Golgi and requires a beta-
RT subunit to function in lipid translocation and secretory vesicle
RT formation.";
RL Plant Cell 20:658-676(2008).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- TISSUE SPECIFICITY: Expressed in flowers. May be restricted to pollen
CC grains. {ECO:0000269|PubMed:18344284}.
CC -!- SIMILARITY: Belongs to the CDC50/LEM3 family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAD34688.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC Sequence=BAD43093.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305};
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DR EMBL; AC006341; AAD34688.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002684; AEE29442.1; -; Genomic_DNA.
DR EMBL; AK175330; BAD43093.1; ALT_INIT; mRNA.
DR PIR; G86298; G86298.
DR RefSeq; NP_173086.2; NM_101502.3.
DR AlphaFoldDB; Q9SA35; -.
DR SMR; Q9SA35; -.
DR STRING; 3702.AT1G16360.1; -.
DR PaxDb; Q9SA35; -.
DR EnsemblPlants; AT1G16360.1; AT1G16360.1; AT1G16360.
DR GeneID; 838205; -.
DR Gramene; AT1G16360.1; AT1G16360.1; AT1G16360.
DR KEGG; ath:AT1G16360; -.
DR Araport; AT1G16360; -.
DR TAIR; locus:2032780; AT1G16360.
DR eggNOG; KOG2952; Eukaryota.
DR HOGENOM; CLU_025025_1_1_1; -.
DR InParanoid; Q9SA35; -.
DR PRO; PR:Q9SA35; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q9SA35; baseline and differential.
DR Genevisible; Q9SA35; AT.
DR GO; GO:0005783; C:endoplasmic reticulum; IBA:GO_Central.
DR GO; GO:0005794; C:Golgi apparatus; IBA:GO_Central.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005634; C:nucleus; HDA:TAIR.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0033036; P:macromolecule localization; IEA:UniProt.
DR InterPro; IPR005045; CDC50/LEM3_fam.
DR PANTHER; PTHR10926; PTHR10926; 1.
DR Pfam; PF03381; CDC50; 1.
DR PIRSF; PIRSF015840; DUF284_TM_euk; 1.
PE 2: Evidence at transcript level;
KW Glycoprotein; Membrane; Reference proteome; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..336
FT /note="Putative ALA-interacting subunit 4"
FT /id="PRO_0000366957"
FT TRANSMEM 36..56
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 290..310
FT /note="Helical"
FT /evidence="ECO:0000255"
FT REGION 127..148
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 127..145
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CARBOHYD 94
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 167
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 329
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
SQ SEQUENCE 336 AA; 38072 MW; D9BE8EA420FC96ED CRC64;
MSTKKHNLLA NFASSDSRFT QQELPACKPI LTPKWVILTF LVSGVVFIPL GVICLFASQG
VIEIVDRYDT DCIPLSSRDN KVRYIQGLED KRCNRTITVT KTMKNPVYVY YQLENYYQNH
RRYVKSRQDG QLRSPKDEHE TKSCAPEDTL GGQPIVPCGL VAWSLFNDTY DFTRNNQKLP
VNKKDISWKS DRESKFGKNV FPKNFQKGSL IGGKSLDQDI PLSEQEDLIV WMRTAALPTF
RKLYGKIDTD LQAGDTIKVL LQNNYNTYSF NGKKKLVLST TSWLGGRNDF LGIAYLTVGS
ICLFLAVSFS VLYLAKPRQL GDPSYLSWNR SAGGGR
