ID   ALL1_BRAJU              Reviewed;         129 AA.
AC   P80207; P80215;
DT   01-OCT-1993, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1993, sequence version 1.
DT   25-MAY-2022, entry version 77.
DE   RecName: Full=Allergen Bra j 1-E;
DE   AltName: Full=Allergen Bra j I;
DE   AltName: Allergen=Bra j 1-E;
DE   Contains:
DE     RecName: Full=Allergen Bra j 1-E small chain;
DE   Contains:
DE     RecName: Full=Allergen Bra j 1-E large chain;
OS   Brassica juncea (Indian mustard) (Sinapis juncea).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Brassiceae; Brassica.
OX   NCBI_TaxID=3707;
RN   [1]
RP   PROTEIN SEQUENCE.
RC   TISSUE=Seed;
RX   PubMed=7688955; DOI=10.1042/bj2930625;
RA   Monsalve R.I., Gonzalez de la Pena M.A., Menendez-Arias L., Lopez-Otin C.,
RA   Villalba M., Rodriguez R.;
RT   "Characterization of a new oriental-mustard (Brassica juncea) allergen, Bra
RT   j IE: detection of an allergenic epitope.";
RL   Biochem. J. 293:625-632(1993).
CC   -!- FUNCTION: This is a 2S seed storage protein.
CC   -!- SUBUNIT: The mature protein consists of a small and a large chain
CC       linked by two disulfide bonds.
CC   -!- ALLERGEN: Causes an allergic reaction in human.
CC   -!- SIMILARITY: Belongs to the 2S seed storage albumins family.
CC       {ECO:0000305}.
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DR   PIR; S35591; S35591.
DR   PIR; S35592; S35592.
DR   AlphaFoldDB; P80207; -.
DR   SMR; P80207; -.
DR   Allergome; 168; Bra j 1.
DR   Allergome; 3161; Bra j 1.0101.
DR   GO; GO:0045735; F:nutrient reservoir activity; IEA:UniProtKB-KW.
DR   CDD; cd00261; AAI_SS; 1.
DR   Gene3D; 1.10.110.10; -; 1.
DR   InterPro; IPR044723; AAI_SS_dom.
DR   InterPro; IPR036312; Bifun_inhib/LTP/seed_sf.
DR   InterPro; IPR016140; Bifunc_inhib/LTP/seed_store.
DR   InterPro; IPR000617; Napin/2SS/CON.
DR   PANTHER; PTHR35496; PTHR35496; 2.
DR   Pfam; PF00234; Tryp_alpha_amyl; 1.
DR   PRINTS; PR00496; NAPIN.
DR   SMART; SM00499; AAI; 1.
DR   SUPFAM; SSF47699; SSF47699; 1.
PE   1: Evidence at protein level;
KW   Allergen; Direct protein sequencing; Disulfide bond; Seed storage protein;
KW   Storage protein.
FT   CHAIN           1..37
FT                   /note="Allergen Bra j 1-E small chain"
FT                   /id="PRO_0000032170"
FT   CHAIN           38..129
FT                   /note="Allergen Bra j 1-E large chain"
FT                   /id="PRO_0000032171"
FT   REGION          28..47
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   VARIANT         6
FT                   /note="F -> I"
FT   VARIANT         20
FT                   /note="R -> K"
FT   NON_CONS        37..38
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   129 AA;  14644 MW;  D6F28E03F62B08F8 CRC64;
     AGPFRFPRCR KEFQQAQHLR ACQQWLHKQA MQSGSGPQPQ GPQQRPPLLQ QCCNELHQEE
     PLCVCPTLKG ASKAVKQQIR QQGQQQGQQG QQLQHEISRI YQTATHLPRV CNIPRVSICP
     FQKTMPGPS