GATD1_XENLA
ID GATD1_XENLA Reviewed; 245 AA.
AC Q7ZXY4;
DT 29-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2003, sequence version 1.
DT 03-AUG-2022, entry version 72.
DE RecName: Full=GATA zinc finger domain-containing protein 1;
GN Name=gatad1;
OS Xenopus laevis (African clawed frog).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX NCBI_TaxID=8355;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Embryo;
RG NIH - Xenopus Gene Collection (XGC) project;
RL Submitted (JAN-2003) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Component of some chromatin complex recruited to chromatin
CC sites methylated 'Lys-4' of histone H3 (H3K4me), with a preference for
CC trimethylated form (H3K4me3). {ECO:0000250|UniProtKB:Q8WUU5}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:Q8WUU5}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; BC044066; AAH44066.1; -; mRNA.
DR RefSeq; NP_001080603.1; NM_001087134.1.
DR AlphaFoldDB; Q7ZXY4; -.
DR DNASU; 380295; -.
DR GeneID; 380295; -.
DR KEGG; xla:380295; -.
DR CTD; 380295; -.
DR Xenbase; XB-GENE-6253912; gatad1.L.
DR OrthoDB; 1259563at2759; -.
DR Proteomes; UP000186698; Chromosome 6L.
DR Bgee; 380295; Expressed in blastula and 19 other tissues.
DR GO; GO:0005634; C:nucleus; ISS:UniProtKB.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR Gene3D; 3.30.50.10; -; 1.
DR InterPro; IPR039050; GATAD1.
DR InterPro; IPR000679; Znf_GATA.
DR InterPro; IPR013088; Znf_NHR/GATA.
DR PANTHER; PTHR13340; PTHR13340; 1.
DR PROSITE; PS50114; GATA_ZN_FINGER_2; 1.
PE 2: Evidence at transcript level;
KW Metal-binding; Nucleus; Reference proteome; Zinc; Zinc-finger.
FT CHAIN 1..245
FT /note="GATA zinc finger domain-containing protein 1"
FT /id="PRO_0000288912"
FT ZN_FING 9..33
FT /note="GATA-type"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00094"
FT REGION 39..110
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 39..80
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 245 AA; 26818 MW; 0C28DE7715BBE6D4 CRC64;
MPLGLKPTCS MCKTNTSSMW KKGSQGEILC NNCSGKSSTA AGGNNNNNSS SSTSGSSSYT
GTTFASTSTS QQSNGGNTKQ SKQEIHRRSA RLRNTKYKAT PAAEKKVSTK GKGRRHIFKL
KNGLYYQIGD VVSVVDEEDG KTYYAQVRGF IQDQYCEKSA ALTWLIPTLS SPKDGFDPST
YIIGPDEDLP RKMECLEFVC HAPSEYFKSR SSPFPTIPTR PEKGFIWTHI GPTPAISIKE
TMANH