GATL8_ARATH
ID GATL8_ARATH Reviewed; 393 AA.
AC O48684;
DT 23-MAR-2010, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-1998, sequence version 1.
DT 03-AUG-2022, entry version 113.
DE RecName: Full=Probable galacturonosyltransferase-like 8;
DE EC=2.4.1.-;
DE AltName: Full=Like glycosyl transferase 9;
GN Name=GATL8; Synonyms=LGT9; OrderedLocusNames=At1g24170; ORFNames=F3I6.10;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=11910074; DOI=10.1126/science.1071006;
RA Seki M., Narusaka M., Kamiya A., Ishida J., Satou M., Sakurai T.,
RA Nakajima M., Enju A., Akiyama K., Oono Y., Muramatsu M., Hayashizaki Y.,
RA Kawai J., Carninci P., Itoh M., Ishii Y., Arakawa T., Shibata K.,
RA Shinagawa A., Shinozaki K.;
RT "Functional annotation of a full-length Arabidopsis cDNA collection.";
RL Science 296:141-145(2002).
RN [4]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=10809443; DOI=10.1023/a:1006368316413;
RA Tavares R., Aubourg S., Lecharny A., Kreis M.;
RT "Organization and structural evolution of four multigene families in
RT Arabidopsis thaliana: AtLCAD, AtLGT, AtMYST and AtHD-GL2.";
RL Plant Mol. Biol. 42:703-717(2000).
RN [5]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=16540543; DOI=10.1073/pnas.0600120103;
RA Sterling J.D., Atmodjo M.A., Inwood S.E., Kumar Kolli V.S., Quigley H.F.,
RA Hahn M.G., Mohnen D.;
RT "Functional identification of an Arabidopsis pectin biosynthetic
RT homogalacturonan galacturonosyltransferase.";
RL Proc. Natl. Acad. Sci. U.S.A. 103:5236-5241(2006).
CC -!- FUNCTION: May be involved in pectin and/or xylans biosynthesis in cell
CC walls. {ECO:0000250}.
CC -!- PATHWAY: Glycan metabolism; pectin biosynthesis.
CC -!- SUBCELLULAR LOCATION: Golgi apparatus membrane {ECO:0000250}; Single-
CC pass type II membrane protein {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the glycosyltransferase 8 family. {ECO:0000305}.
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DR EMBL; AC002396; AAC00579.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE30491.1; -; Genomic_DNA.
DR EMBL; AK119069; BAC43645.1; -; mRNA.
DR PIR; T00647; T00647.
DR RefSeq; NP_173827.1; NM_102263.3.
DR AlphaFoldDB; O48684; -.
DR SMR; O48684; -.
DR STRING; 3702.AT1G24170.1; -.
DR CAZy; GT8; Glycosyltransferase Family 8.
DR PaxDb; O48684; -.
DR PRIDE; O48684; -.
DR ProteomicsDB; 248564; -.
DR EnsemblPlants; AT1G24170.1; AT1G24170.1; AT1G24170.
DR GeneID; 839030; -.
DR Gramene; AT1G24170.1; AT1G24170.1; AT1G24170.
DR KEGG; ath:AT1G24170; -.
DR Araport; AT1G24170; -.
DR TAIR; locus:2032357; AT1G24170.
DR eggNOG; ENOG502QTN8; Eukaryota.
DR HOGENOM; CLU_034713_0_0_1; -.
DR InParanoid; O48684; -.
DR OMA; TQYFTSG; -.
DR OrthoDB; 1520602at2759; -.
DR PhylomeDB; O48684; -.
DR UniPathway; UPA00845; -.
DR PRO; PR:O48684; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; O48684; baseline and differential.
DR Genevisible; O48684; AT.
DR GO; GO:0005794; C:Golgi apparatus; IBA:GO_Central.
DR GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0047262; F:polygalacturonate 4-alpha-galacturonosyltransferase activity; ISS:TAIR.
DR GO; GO:0071555; P:cell wall organization; IEA:UniProtKB-KW.
DR GO; GO:0045489; P:pectin biosynthetic process; IEA:UniProtKB-UniPathway.
DR Gene3D; 3.90.550.10; -; 1.
DR InterPro; IPR002495; Glyco_trans_8.
DR InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR Pfam; PF01501; Glyco_transf_8; 1.
DR SUPFAM; SSF53448; SSF53448; 1.
PE 2: Evidence at transcript level;
KW Cell wall biogenesis/degradation; Glycoprotein; Glycosyltransferase;
KW Golgi apparatus; Membrane; Reference proteome; Signal-anchor; Transferase;
KW Transmembrane; Transmembrane helix.
FT CHAIN 1..393
FT /note="Probable galacturonosyltransferase-like 8"
FT /id="PRO_0000392610"
FT TOPO_DOM 1..4
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 5..25
FT /note="Helical; Signal-anchor for type II membrane protein"
FT /evidence="ECO:0000255"
FT TOPO_DOM 26..393
FT /note="Lumenal"
FT /evidence="ECO:0000255"
FT CARBOHYD 226
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
SQ SEQUENCE 393 AA; 43989 MW; 8D63C97986F65CAF CRC64;
MSSRFSLTVV CLIALLPFVV GIRLIPARIT SVGDGGGGGG NNGFSKLGPF MEAPEYRNGK
ECVSSSVNRE NFVSSSSSSN DPSLVHIAMT LDSEYLRGSI AAVHSVLRHA SCPENVFFHF
IAAEFDSASP RVLSQLVRST FPSLNFKVYI FREDTVINLI SSSIRLALEN PLNYARNYLG
DILDRSVERV IYLDSDVITV DDITKLWNTV LTGSRVIGAP EYCHANFTQY FTSGFWSDPA
LPGLISGQKP CYFNTGVMVM DLVRWREGNY REKLEQWMQL QKKMRIYDLG SLPPFLLVFA
GNVEAIDHRW NQHGLGGDNI RGSCRSLHPG PVSLLHWSGK GKPWVRLDEK RPCPLDHLWE
PYDLYKHKIE RAKDQSLLGF ASLSELTDDS SFL
