ALL7_ASPFU
ID ALL7_ASPFU Reviewed; 270 AA.
AC O42799; Q4WNR3;
DT 20-JUN-2001, integrated into UniProtKB/Swiss-Prot.
DT 06-DEC-2005, sequence version 2.
DT 25-MAY-2022, entry version 93.
DE RecName: Full=Allergen Asp f 7;
DE AltName: Allergen=Asp f 7;
DE Flags: Precursor;
GN ORFNames=AFUA_4G06670;
OS Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC
OS A1100) (Aspergillus fumigatus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Fumigati.
OX NCBI_TaxID=330879;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100;
RX PubMed=16372009; DOI=10.1038/nature04332;
RA Nierman W.C., Pain A., Anderson M.J., Wortman J.R., Kim H.S., Arroyo J.,
RA Berriman M., Abe K., Archer D.B., Bermejo C., Bennett J.W., Bowyer P.,
RA Chen D., Collins M., Coulsen R., Davies R., Dyer P.S., Farman M.L.,
RA Fedorova N., Fedorova N.D., Feldblyum T.V., Fischer R., Fosker N.,
RA Fraser A., Garcia J.L., Garcia M.J., Goble A., Goldman G.H., Gomi K.,
RA Griffith-Jones S., Gwilliam R., Haas B.J., Haas H., Harris D.E.,
RA Horiuchi H., Huang J., Humphray S., Jimenez J., Keller N., Khouri H.,
RA Kitamoto K., Kobayashi T., Konzack S., Kulkarni R., Kumagai T., Lafton A.,
RA Latge J.-P., Li W., Lord A., Lu C., Majoros W.H., May G.S., Miller B.L.,
RA Mohamoud Y., Molina M., Monod M., Mouyna I., Mulligan S., Murphy L.D.,
RA O'Neil S., Paulsen I., Penalva M.A., Pertea M., Price C., Pritchard B.L.,
RA Quail M.A., Rabbinowitsch E., Rawlins N., Rajandream M.A., Reichard U.,
RA Renauld H., Robson G.D., Rodriguez de Cordoba S., Rodriguez-Pena J.M.,
RA Ronning C.M., Rutter S., Salzberg S.L., Sanchez M., Sanchez-Ferrero J.C.,
RA Saunders D., Seeger K., Squares R., Squares S., Takeuchi M., Tekaia F.,
RA Turner G., Vazquez de Aldana C.R., Weidman J., White O., Woodward J.R.,
RA Yu J.-H., Fraser C.M., Galagan J.E., Asai K., Machida M., Hall N.,
RA Barrell B.G., Denning D.W.;
RT "Genomic sequence of the pathogenic and allergenic filamentous fungus
RT Aspergillus fumigatus.";
RL Nature 438:1151-1156(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [MRNA] OF 159-270.
RC STRAIN=ATCC 42202 / AF-102 / Ag 507;
RX PubMed=9482698; DOI=10.1159/000023889;
RA Crameri R.;
RT "Recombinant Aspergillus fumigatus allergens: from the nucleotide sequences
RT to clinical applications.";
RL Int. Arch. Allergy Immunol. 115:99-114(1998).
CC -!- ALLERGEN: Causes an allergic reaction in human.
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DR EMBL; AAHF01000005; EAL90121.1; -; Genomic_DNA.
DR EMBL; AJ223315; CAA11255.1; -; mRNA.
DR RefSeq; XP_752159.1; XM_747066.1.
DR AlphaFoldDB; O42799; -.
DR SMR; O42799; -.
DR STRING; 746128.CADAFUBP00006201; -.
DR Allergome; 3125; Asp f 7.0101.
DR Allergome; 77; Asp f 7.
DR EnsemblFungi; EAL90121; EAL90121; AFUA_4G06670.
DR GeneID; 3509245; -.
DR KEGG; afm:AFUA_4G06670; -.
DR VEuPathDB; FungiDB:Afu4g06670; -.
DR eggNOG; ENOG502S2E4; Eukaryota.
DR HOGENOM; CLU_052701_1_0_1; -.
DR InParanoid; O42799; -.
DR OMA; WETVTDI; -.
DR OrthoDB; 1540699at2759; -.
DR Proteomes; UP000002530; Chromosome 4.
DR Gene3D; 2.40.40.10; -; 1.
DR InterPro; IPR036908; RlpA-like_sf.
DR SUPFAM; SSF50685; SSF50685; 1.
PE 1: Evidence at protein level;
KW Allergen; Reference proteome; Signal.
FT SIGNAL 1..21
FT /evidence="ECO:0000255"
FT CHAIN 22..270
FT /note="Allergen Asp f 7"
FT /id="PRO_0000043347"
FT REGION 53..97
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 113..167
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 55..69
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 70..97
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 128..166
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 270 AA; 27482 MW; B991154D0A161587 CRC64;
MAPIFKSLAL VSALFAAISS AAPVNLDKRE VDVVWTTVTT VVWTTIDVTT TIYPTPQAPT
PPVVESTPTP TPSAAPEQAE PIETSTQPET TKSQPTQPSV ATFIPVAAAA AAADSAAPIP
EEPAPQPATT AAPSTSTTTQ AAPSAPPAAN SGSTEKAASS GYSGPCSKGS PCVGQLTYYD
TATSASAPSS CGLTNDGFSE NVVALPVGIM TDADCGKTVT ITYNGITKTA TVVDKCMGCK
PTDLDASRHL FGELADFSAG RIDGMSWYFN