GATZ_ECOSE
ID GATZ_ECOSE Reviewed; 420 AA.
AC B6HYT6;
DT 05-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT 16-DEC-2008, sequence version 1.
DT 03-AUG-2022, entry version 73.
DE RecName: Full=D-tagatose-1,6-bisphosphate aldolase subunit GatZ {ECO:0000255|HAMAP-Rule:MF_01296};
GN Name=gatZ {ECO:0000255|HAMAP-Rule:MF_01296}; OrderedLocusNames=ECSE_2364;
OS Escherichia coli (strain SE11).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=409438;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SE11;
RX PubMed=18931093; DOI=10.1093/dnares/dsn026;
RA Oshima K., Toh H., Ogura Y., Sasamoto H., Morita H., Park S.-H., Ooka T.,
RA Iyoda S., Taylor T.D., Hayashi T., Itoh K., Hattori M.;
RT "Complete genome sequence and comparative analysis of the wild-type
RT commensal Escherichia coli strain SE11 isolated from a healthy adult.";
RL DNA Res. 15:375-386(2008).
CC -!- FUNCTION: Component of the tagatose-1,6-bisphosphate aldolase GatYZ
CC that is required for full activity and stability of the Y subunit.
CC Could have a chaperone-like function for the proper and stable folding
CC of GatY. When expressed alone, GatZ does not show any aldolase
CC activity. Is involved in the catabolism of galactitol.
CC {ECO:0000255|HAMAP-Rule:MF_01296}.
CC -!- PATHWAY: Carbohydrate metabolism; D-tagatose 6-phosphate degradation;
CC D-glyceraldehyde 3-phosphate and glycerone phosphate from D-tagatose 6-
CC phosphate: step 2/2. {ECO:0000255|HAMAP-Rule:MF_01296}.
CC -!- SUBUNIT: Forms a complex with GatY. {ECO:0000255|HAMAP-Rule:MF_01296}.
CC -!- SIMILARITY: Belongs to the GatZ/KbaZ family. GatZ subfamily.
CC {ECO:0000255|HAMAP-Rule:MF_01296}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AP009240; BAG77888.1; -; Genomic_DNA.
DR RefSeq; WP_000853892.1; NC_011415.1.
DR AlphaFoldDB; B6HYT6; -.
DR SMR; B6HYT6; -.
DR EnsemblBacteria; BAG77888; BAG77888; ECSE_2364.
DR KEGG; ecy:ECSE_2364; -.
DR HOGENOM; CLU_053334_0_0_6; -.
DR OMA; AINAVHV; -.
DR UniPathway; UPA00704; UER00716.
DR Proteomes; UP000008199; Chromosome.
DR GO; GO:2001059; P:D-tagatose 6-phosphate catabolic process; IEA:UniProtKB-UniPathway.
DR GO; GO:0019404; P:galactitol catabolic process; IEA:UniProtKB-UniRule.
DR Gene3D; 3.20.20.70; -; 1.
DR HAMAP; MF_01296; Tagatose_aldol_GatZ; 1.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR012062; GatZ/KbaZ-like.
DR InterPro; IPR023436; TagBP_ald_GatZ.
DR Pfam; PF08013; GatZ_KbaZ-like; 1.
DR PIRSF; PIRSF009264; TagBP_ald_AgaZ; 1.
DR TIGRFAMs; TIGR02810; agaZ_gatZ; 1.
PE 3: Inferred from homology;
KW Galactitol metabolism.
FT CHAIN 1..420
FT /note="D-tagatose-1,6-bisphosphate aldolase subunit GatZ"
FT /id="PRO_0000372492"
SQ SEQUENCE 420 AA; 47139 MW; 9F278F7599943827 CRC64;
MKTLIARHKA GEHIGICSVC SAHPLVIEAA LAFDRNSTRK VLIEATSNQV NQFGGYTGMT
PADFREFVFT IADKVGFARE RIILGGDHLG PNCWQQENAD AAMEKSVELV KEYVRAGFSK
IHLDASMSCA GDPIPLAPET VAERAAVLCF AAESVATDCQ REQLSYVIGT EVPVPGGEAS
AIQSVHITHV EDTANTLRTH QKAFIARGLT EALTRVIAIV VQPGVEFDHS NIIHYQPQEA
QPLAQWIENT RMVYEAHSTD YQTRTAYWEL VRDHFAILKV GPALTFALRE AIFALAQIEQ
ELIAPENRSG CLAVIEEVML DEPQYWKKYY RTGFNDSLLD IRYSLSDRIR YYWPHSRIKN
SVETMMVNLE GVDIPLGMIS QYLPKQFERI QSGELSAIPH QLIMDKIYDV LRAYRYGCAE