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ALL7_DERFA
ID   ALL7_DERFA              Reviewed;         213 AA.
AC   Q26456;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1997, sequence version 1.
DT   25-MAY-2022, entry version 60.
DE   RecName: Full=Mite allergen Der f 7;
DE   AltName: Full=Allergen Der f VII;
DE   AltName: Allergen=Der f 7;
DE   Flags: Precursor;
GN   Name=DERF7;
OS   Dermatophagoides farinae (American house dust mite).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari;
OC   Acariformes; Sarcoptiformes; Astigmata; Psoroptidia; Analgoidea;
OC   Pyroglyphidae; Dermatophagoidinae; Dermatophagoides.
OX   NCBI_TaxID=6954;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RX   PubMed=8556554; DOI=10.1111/j.1365-2222.1995.tb00403.x;
RA   Shen H.-D., Chua K.-Y., Lin W.L., Hsieh K.-H., Thomas W.R.;
RT   "Molecular cloning and immunological characterization of the house dust
RT   mite allergen Der f 7.";
RL   Clin. Exp. Allergy 25:1000-1006(1995).
CC   -!- SUBCELLULAR LOCATION: Secreted.
CC   -!- ALLERGEN: Causes an allergic reaction in human. Common symptoms of mite
CC       allergy are bronchial asthma, allergic rhinitis and conjunctivitis.
CC   -!- SIMILARITY: Belongs to the mite group 7 allergen family. {ECO:0000305}.
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DR   EMBL; S80655; AAB35977.1; -; mRNA.
DR   PDB; 3UV1; X-ray; 2.00 A; A/B=18-213.
DR   PDBsum; 3UV1; -.
DR   AlphaFoldDB; Q26456; -.
DR   SMR; Q26456; -.
DR   Allergome; 307; Der f 7.
DR   Allergome; 3256; Der f 7.0101.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   Gene3D; 3.15.10.50; -; 1.
DR   InterPro; IPR038602; Mite_allergen_7_sf.
DR   InterPro; IPR020234; Mite_allergen_group-7.
DR   Pfam; PF16984; Grp7_allergen; 1.
PE   1: Evidence at protein level;
KW   3D-structure; Allergen; Glycoprotein; Secreted; Signal.
FT   SIGNAL          1..17
FT                   /evidence="ECO:0000255"
FT   CHAIN           18..213
FT                   /note="Mite allergen Der f 7"
FT                   /id="PRO_0000001184"
FT   CARBOHYD        151
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   HELIX           24..41
FT                   /evidence="ECO:0007829|PDB:3UV1"
FT   STRAND          43..51
FT                   /evidence="ECO:0007829|PDB:3UV1"
FT   STRAND          54..61
FT                   /evidence="ECO:0007829|PDB:3UV1"
FT   STRAND          63..79
FT                   /evidence="ECO:0007829|PDB:3UV1"
FT   HELIX           81..83
FT                   /evidence="ECO:0007829|PDB:3UV1"
FT   STRAND          84..89
FT                   /evidence="ECO:0007829|PDB:3UV1"
FT   STRAND          91..95
FT                   /evidence="ECO:0007829|PDB:3UV1"
FT   STRAND          98..110
FT                   /evidence="ECO:0007829|PDB:3UV1"
FT   STRAND          112..122
FT                   /evidence="ECO:0007829|PDB:3UV1"
FT   STRAND          128..136
FT                   /evidence="ECO:0007829|PDB:3UV1"
FT   STRAND          139..150
FT                   /evidence="ECO:0007829|PDB:3UV1"
FT   STRAND          153..159
FT                   /evidence="ECO:0007829|PDB:3UV1"
FT   STRAND          163..169
FT                   /evidence="ECO:0007829|PDB:3UV1"
FT   HELIX           177..211
FT                   /evidence="ECO:0007829|PDB:3UV1"
SQ   SEQUENCE   213 AA;  23627 MW;  3CF1F529107B7808 CRC64;
     MMKFLLIAAV AFVAVSADPI HYDKITEEIN KAIDDAIAAI EQSETIDPMK VPDHADKFER
     HVGIVDFKGE LAMRNIEARG LKQMKRQGDA NVKGEEGIVK AHLLIGVHDD IVSMEYDLAY
     KLGDLHPTTH VISDIQDFVV ALSLEISDEG NITMTSFEVR QFANVVNHIG GLSILDPIFG
     VLSDVLTAIF QDTVRKEMTK VLAPAFKREL EKN
 
 
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