ID   GATZ_KLEP7              Reviewed;         423 AA.
AC   A6TEF8;
DT   05-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT   21-AUG-2007, sequence version 1.
DT   03-AUG-2022, entry version 77.
DE   RecName: Full=D-tagatose-1,6-bisphosphate aldolase subunit GatZ {ECO:0000255|HAMAP-Rule:MF_01296};
GN   Name=gatZ {ECO:0000255|HAMAP-Rule:MF_01296};
GN   OrderedLocusNames=KPN78578_35180; ORFNames=KPN_03547;
OS   Klebsiella pneumoniae subsp. pneumoniae (strain ATCC 700721 / MGH 78578).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella.
OX   NCBI_TaxID=272620;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700721 / MGH 78578;
RG   The Klebsiella pneumonia Genome Sequencing Project;
RA   McClelland M., Sanderson E.K., Spieth J., Clifton W.S., Latreille P.,
RA   Sabo A., Pepin K., Bhonagiri V., Porwollik S., Ali J., Wilson R.K.;
RL   Submitted (SEP-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Component of the tagatose-1,6-bisphosphate aldolase GatYZ
CC       that is required for full activity and stability of the Y subunit.
CC       Could have a chaperone-like function for the proper and stable folding
CC       of GatY. When expressed alone, GatZ does not show any aldolase
CC       activity. Is involved in the catabolism of galactitol.
CC       {ECO:0000255|HAMAP-Rule:MF_01296}.
CC   -!- PATHWAY: Carbohydrate metabolism; D-tagatose 6-phosphate degradation;
CC       D-glyceraldehyde 3-phosphate and glycerone phosphate from D-tagatose 6-
CC       phosphate: step 2/2. {ECO:0000255|HAMAP-Rule:MF_01296}.
CC   -!- SUBUNIT: Forms a complex with GatY. {ECO:0000255|HAMAP-Rule:MF_01296}.
CC   -!- SIMILARITY: Belongs to the GatZ/KbaZ family. GatZ subfamily.
CC       {ECO:0000255|HAMAP-Rule:MF_01296}.
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DR   EMBL; CP000647; ABR78942.1; -; Genomic_DNA.
DR   RefSeq; WP_002918071.1; NC_009648.1.
DR   AlphaFoldDB; A6TEF8; -.
DR   SMR; A6TEF8; -.
DR   STRING; 272620.KPN_03547; -.
DR   EnsemblBacteria; ABR78942; ABR78942; KPN_03547.
DR   KEGG; kpn:KPN_03547; -.
DR   HOGENOM; CLU_053334_0_0_6; -.
DR   OMA; AINAVHV; -.
DR   UniPathway; UPA00704; UER00716.
DR   Proteomes; UP000000265; Chromosome.
DR   GO; GO:2001059; P:D-tagatose 6-phosphate catabolic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0019404; P:galactitol catabolic process; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.20.20.70; -; 1.
DR   HAMAP; MF_01296; Tagatose_aldol_GatZ; 1.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR012062; GatZ/KbaZ-like.
DR   InterPro; IPR023436; TagBP_ald_GatZ.
DR   Pfam; PF08013; GatZ_KbaZ-like; 1.
DR   PIRSF; PIRSF009264; TagBP_ald_AgaZ; 1.
DR   TIGRFAMs; TIGR02810; agaZ_gatZ; 1.
PE   3: Inferred from homology;
KW   Galactitol metabolism; Reference proteome.
FT   CHAIN           1..423
FT                   /note="D-tagatose-1,6-bisphosphate aldolase subunit GatZ"
FT                   /id="PRO_0000372506"
SQ   SEQUENCE   423 AA;  47116 MW;  016A6084A0B0CEBD CRC64;
     MKDIITRHKS GEHIGICSVC SAHPLVIEAA LRFDLSTNNK VLIEATSNQV NQFGGYTGMQ
     PADFRDFVYN IARTVGFPAE RIILGGDHLG PNCWQDEPAA VAMEKSIDLI KAYVAAGFSK
     IHLDASMSCA DDPVPLDPGV VAERAARLCQ AAEETASDEQ KRHLTYVIGT EVPVPGGEAS
     TIGSVHVTRA QDAAATLETH EAAFRKLGLD AALERVIAIV VQPGVEFDHT QIIHYQPQEA
     KALSAWIEST PMVYEAHSTD YQTRQAYRAL VRDHFAILKV GPALTFALRE AIFALAQMEN
     ELIAPESRSR VMEVIDEVML NEPGYWKKYY RPTWSQAMVD IHFSLSDRIR YYWPHPRIRQ
     SVEKLIANLT DAKLPLGLIS QYMPVQFERL SLNELNAEPH ALILDKIQDV LRAYRYGCSS
     ETA