ID   GATZ_SALNS              Reviewed;         423 AA.
AC   B4T6C0;
DT   05-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT   05-MAY-2009, sequence version 2.
DT   03-AUG-2022, entry version 70.
DE   RecName: Full=D-tagatose-1,6-bisphosphate aldolase subunit GatZ {ECO:0000255|HAMAP-Rule:MF_01296};
GN   Name=gatZ {ECO:0000255|HAMAP-Rule:MF_01296};
GN   OrderedLocusNames=SNSL254_A3515;
OS   Salmonella newport (strain SL254).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Salmonella.
OX   NCBI_TaxID=423368;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SL254;
RX   PubMed=21602358; DOI=10.1128/jb.00297-11;
RA   Fricke W.F., Mammel M.K., McDermott P.F., Tartera C., White D.G.,
RA   Leclerc J.E., Ravel J., Cebula T.A.;
RT   "Comparative genomics of 28 Salmonella enterica isolates: evidence for
RT   CRISPR-mediated adaptive sublineage evolution.";
RL   J. Bacteriol. 193:3556-3568(2011).
CC   -!- FUNCTION: Component of the tagatose-1,6-bisphosphate aldolase GatYZ
CC       that is required for full activity and stability of the Y subunit.
CC       Could have a chaperone-like function for the proper and stable folding
CC       of GatY. When expressed alone, GatZ does not show any aldolase
CC       activity. Is involved in the catabolism of galactitol.
CC       {ECO:0000255|HAMAP-Rule:MF_01296}.
CC   -!- PATHWAY: Carbohydrate metabolism; D-tagatose 6-phosphate degradation;
CC       D-glyceraldehyde 3-phosphate and glycerone phosphate from D-tagatose 6-
CC       phosphate: step 2/2. {ECO:0000255|HAMAP-Rule:MF_01296}.
CC   -!- SUBUNIT: Forms a complex with GatY. {ECO:0000255|HAMAP-Rule:MF_01296}.
CC   -!- SIMILARITY: Belongs to the GatZ/KbaZ family. GatZ subfamily.
CC       {ECO:0000255|HAMAP-Rule:MF_01296}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=ACF62260.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; CP001113; ACF62260.1; ALT_INIT; Genomic_DNA.
DR   RefSeq; WP_000658734.1; NZ_CCMR01000001.1.
DR   AlphaFoldDB; B4T6C0; -.
DR   SMR; B4T6C0; -.
DR   EnsemblBacteria; ACF62260; ACF62260; SNSL254_A3515.
DR   KEGG; see:SNSL254_A3515; -.
DR   HOGENOM; CLU_053334_0_0_6; -.
DR   UniPathway; UPA00704; UER00716.
DR   Proteomes; UP000008824; Chromosome.
DR   GO; GO:2001059; P:D-tagatose 6-phosphate catabolic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0019404; P:galactitol catabolic process; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.20.20.70; -; 1.
DR   HAMAP; MF_01296; Tagatose_aldol_GatZ; 1.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR012062; GatZ/KbaZ-like.
DR   InterPro; IPR023436; TagBP_ald_GatZ.
DR   Pfam; PF08013; GatZ_KbaZ-like; 1.
DR   PIRSF; PIRSF009264; TagBP_ald_AgaZ; 1.
DR   TIGRFAMs; TIGR02810; agaZ_gatZ; 1.
PE   3: Inferred from homology;
KW   Galactitol metabolism.
FT   CHAIN           1..423
FT                   /note="D-tagatose-1,6-bisphosphate aldolase subunit GatZ"
FT                   /id="PRO_0000372513"
SQ   SEQUENCE   423 AA;  47230 MW;  684C35C1ADB76E59 CRC64;
     MKEIISRHKA GEQIGICSVC SAHPLVIESA LRFDLNSGNK VLIEATSNQV NQFGGYTGMK
     PADFRDFVYG IAQEVGFPRE RLILGGDHLG PNCWQNEPAA AAMEKSVELI KAYVAAGFSK
     IHLDASMSCA DDPTPLDPMV VAKRAALLCQ AAETTATDEQ KRHLTYVIGT EVPVPGGEAS
     AINAVHVTRE QDAARTLQTH QAAFRVLGLD EALNRVIAIV VQPGVEFDHT QIIHYQPQAA
     QALSAWIKET PMVYEAHSTD YQTRQAYRAL VRDHYAILKV GPALTFALRE AIFALAQMEN
     ELISPEQRSR VLEVIDEVML NEPGYWKKYY RPTWSQAMVD IHFSLSDRIR YYWPHPRIRQ
     SVEKLIANLN NVTLPLGLIS QFMPVQFERL SEGVLTPTPH NLIIDKIQDV LRAYRFGCTP
     DVA