GATZ_SALPA
ID GATZ_SALPA Reviewed; 423 AA.
AC Q5PL82;
DT 05-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT 04-JAN-2005, sequence version 1.
DT 03-AUG-2022, entry version 86.
DE RecName: Full=D-tagatose-1,6-bisphosphate aldolase subunit GatZ {ECO:0000255|HAMAP-Rule:MF_01296};
GN Name=gatZ {ECO:0000255|HAMAP-Rule:MF_01296}; OrderedLocusNames=SPA3126;
OS Salmonella paratyphi A (strain ATCC 9150 / SARB42).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Salmonella.
OX NCBI_TaxID=295319;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 9150 / SARB42;
RX PubMed=15531882; DOI=10.1038/ng1470;
RA McClelland M., Sanderson K.E., Clifton S.W., Latreille P., Porwollik S.,
RA Sabo A., Meyer R., Bieri T., Ozersky P., McLellan M., Harkins C.R.,
RA Wang C., Nguyen C., Berghoff A., Elliott G., Kohlberg S., Strong C., Du F.,
RA Carter J., Kremizki C., Layman D., Leonard S., Sun H., Fulton L., Nash W.,
RA Miner T., Minx P., Delehaunty K., Fronick C., Magrini V., Nhan M.,
RA Warren W., Florea L., Spieth J., Wilson R.K.;
RT "Comparison of genome degradation in Paratyphi A and Typhi, human-
RT restricted serovars of Salmonella enterica that cause typhoid.";
RL Nat. Genet. 36:1268-1274(2004).
CC -!- FUNCTION: Component of the tagatose-1,6-bisphosphate aldolase GatYZ
CC that is required for full activity and stability of the Y subunit.
CC Could have a chaperone-like function for the proper and stable folding
CC of GatY. When expressed alone, GatZ does not show any aldolase
CC activity. Is involved in the catabolism of galactitol.
CC {ECO:0000255|HAMAP-Rule:MF_01296}.
CC -!- PATHWAY: Carbohydrate metabolism; D-tagatose 6-phosphate degradation;
CC D-glyceraldehyde 3-phosphate and glycerone phosphate from D-tagatose 6-
CC phosphate: step 2/2. {ECO:0000255|HAMAP-Rule:MF_01296}.
CC -!- SUBUNIT: Forms a complex with GatY. {ECO:0000255|HAMAP-Rule:MF_01296}.
CC -!- SIMILARITY: Belongs to the GatZ/KbaZ family. GatZ subfamily.
CC {ECO:0000255|HAMAP-Rule:MF_01296}.
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DR EMBL; CP000026; AAV78955.1; -; Genomic_DNA.
DR RefSeq; WP_000658627.1; NC_006511.1.
DR AlphaFoldDB; Q5PL82; -.
DR SMR; Q5PL82; -.
DR EnsemblBacteria; AAV78955; AAV78955; SPA3126.
DR KEGG; spt:SPA3126; -.
DR HOGENOM; CLU_053334_0_0_6; -.
DR OMA; AINAVHV; -.
DR UniPathway; UPA00704; UER00716.
DR Proteomes; UP000008185; Chromosome.
DR GO; GO:2001059; P:D-tagatose 6-phosphate catabolic process; IEA:UniProtKB-UniPathway.
DR GO; GO:0019404; P:galactitol catabolic process; IEA:UniProtKB-UniRule.
DR Gene3D; 3.20.20.70; -; 1.
DR HAMAP; MF_01296; Tagatose_aldol_GatZ; 1.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR012062; GatZ/KbaZ-like.
DR InterPro; IPR023436; TagBP_ald_GatZ.
DR Pfam; PF08013; GatZ_KbaZ-like; 1.
DR PIRSF; PIRSF009264; TagBP_ald_AgaZ; 1.
DR TIGRFAMs; TIGR02810; agaZ_gatZ; 1.
PE 3: Inferred from homology;
KW Galactitol metabolism.
FT CHAIN 1..423
FT /note="D-tagatose-1,6-bisphosphate aldolase subunit GatZ"
FT /id="PRO_0000372514"
SQ SEQUENCE 423 AA; 47262 MW; 8228B4D79D1F8EC1 CRC64;
MKEIIARHKA GEHLGICSVC SAHPLVIESA LLFDLNTDNK VLIEATSNQV NQFGGYTGMK
PADFRDFVYG IAQEVGFPRE RLILGGDHLG PNCWQNEPAA AAMEKSVELI KAYVAAGFSK
IHLDASMSCA DDPTPLDPMV VARRAAVLCK AAEETANEEQ KCHLTYVIGT EVPVPGGEAS
TIGSVHVTRE VDAARTLETH QIAFRESGLE EALSRVIAIV VQPGVEFDHT QIIHYQPQAA
QALSAWIKET PMVYEAHSTD YQTRQAYRAL VRDHYAILKV GPALTFALRE AIFALAQMEN
ELISPEQRSR VLEVIDEVML NEPGYWKKYY RPTWSQAMVD IHFSLSDRIR YYWPHPRIRQ
SVEKLIANLN NVTLPLGLIS QFMPVQFERL SEGVLTPTPH NLIIDKIQDV LRAYRFGCTP
DVA