ID   GATZ_SALSV              Reviewed;         423 AA.
AC   B4TWB1;
DT   05-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT   23-SEP-2008, sequence version 1.
DT   03-AUG-2022, entry version 72.
DE   RecName: Full=D-tagatose-1,6-bisphosphate aldolase subunit GatZ {ECO:0000255|HAMAP-Rule:MF_01296};
GN   Name=gatZ {ECO:0000255|HAMAP-Rule:MF_01296}; OrderedLocusNames=SeSA_A3446;
OS   Salmonella schwarzengrund (strain CVM19633).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Salmonella.
OX   NCBI_TaxID=439843;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CVM19633;
RX   PubMed=21602358; DOI=10.1128/jb.00297-11;
RA   Fricke W.F., Mammel M.K., McDermott P.F., Tartera C., White D.G.,
RA   Leclerc J.E., Ravel J., Cebula T.A.;
RT   "Comparative genomics of 28 Salmonella enterica isolates: evidence for
RT   CRISPR-mediated adaptive sublineage evolution.";
RL   J. Bacteriol. 193:3556-3568(2011).
CC   -!- FUNCTION: Component of the tagatose-1,6-bisphosphate aldolase GatYZ
CC       that is required for full activity and stability of the Y subunit.
CC       Could have a chaperone-like function for the proper and stable folding
CC       of GatY. When expressed alone, GatZ does not show any aldolase
CC       activity. Is involved in the catabolism of galactitol.
CC       {ECO:0000255|HAMAP-Rule:MF_01296}.
CC   -!- PATHWAY: Carbohydrate metabolism; D-tagatose 6-phosphate degradation;
CC       D-glyceraldehyde 3-phosphate and glycerone phosphate from D-tagatose 6-
CC       phosphate: step 2/2. {ECO:0000255|HAMAP-Rule:MF_01296}.
CC   -!- SUBUNIT: Forms a complex with GatY. {ECO:0000255|HAMAP-Rule:MF_01296}.
CC   -!- SIMILARITY: Belongs to the GatZ/KbaZ family. GatZ subfamily.
CC       {ECO:0000255|HAMAP-Rule:MF_01296}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CP001127; ACF91272.1; -; Genomic_DNA.
DR   RefSeq; WP_001530800.1; NC_011094.1.
DR   AlphaFoldDB; B4TWB1; -.
DR   SMR; B4TWB1; -.
DR   EnsemblBacteria; ACF91272; ACF91272; SeSA_A3446.
DR   KEGG; sew:SeSA_A3446; -.
DR   HOGENOM; CLU_053334_0_0_6; -.
DR   OMA; AINAVHV; -.
DR   UniPathway; UPA00704; UER00716.
DR   Proteomes; UP000001865; Chromosome.
DR   GO; GO:2001059; P:D-tagatose 6-phosphate catabolic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0019404; P:galactitol catabolic process; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.20.20.70; -; 1.
DR   HAMAP; MF_01296; Tagatose_aldol_GatZ; 1.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR012062; GatZ/KbaZ-like.
DR   InterPro; IPR023436; TagBP_ald_GatZ.
DR   Pfam; PF08013; GatZ_KbaZ-like; 1.
DR   PIRSF; PIRSF009264; TagBP_ald_AgaZ; 1.
DR   TIGRFAMs; TIGR02810; agaZ_gatZ; 1.
PE   3: Inferred from homology;
KW   Galactitol metabolism.
FT   CHAIN           1..423
FT                   /note="D-tagatose-1,6-bisphosphate aldolase subunit GatZ"
FT                   /id="PRO_0000372517"
SQ   SEQUENCE   423 AA;  47294 MW;  C29EA4D8CF6A637E CRC64;
     MKEIISRHKA GEQIGICSVC SAHPLVIESA LRFDLNSGNK VLIEATSNQV NQFGGYTGMK
     PADFRDFVYG IAQEVGFPRE RLILGGDHLG PNCWQNEPAD TAMEKSVELI KAYVAAGFSK
     IHLDASMSCA DDPTPLDPMV VAKRAALLCQ AAETTATDEQ KRHLTYVIGT EVPVPGGEAS
     AINAVHVTRE QDAARTLQTH QAAFRALGLD EALNRVIAIV VQPGVEFDHT QIIHYQPQAA
     QALSAWIKET PMVYEAHSTD YQTRQAYRAL VRDHYAILKV GPALTFALRE AIFALAQMEN
     ELVSPEQRSR VMEVIDEVML NEPGYWKKYY RPTWSQAMID IHFSLSDRIR YYWPHPRIRQ
     SVEKLIANLN NVTLPLGLIS QFMPVQFERL SEGVLTPTPH NLIIDKIQDV LRAYRFGCTP
     DVA