ID   GATZ_SALTY              Reviewed;         423 AA.
AC   Q8ZLV1;
DT   05-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2002, sequence version 1.
DT   03-AUG-2022, entry version 94.
DE   RecName: Full=D-tagatose-1,6-bisphosphate aldolase subunit GatZ {ECO:0000255|HAMAP-Rule:MF_01296};
GN   Name=gatZ {ECO:0000255|HAMAP-Rule:MF_01296}; OrderedLocusNames=STM3257;
OS   Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Salmonella.
OX   NCBI_TaxID=99287;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LT2 / SGSC1412 / ATCC 700720;
RX   PubMed=11677609; DOI=10.1038/35101614;
RA   McClelland M., Sanderson K.E., Spieth J., Clifton S.W., Latreille P.,
RA   Courtney L., Porwollik S., Ali J., Dante M., Du F., Hou S., Layman D.,
RA   Leonard S., Nguyen C., Scott K., Holmes A., Grewal N., Mulvaney E.,
RA   Ryan E., Sun H., Florea L., Miller W., Stoneking T., Nhan M., Waterston R.,
RA   Wilson R.K.;
RT   "Complete genome sequence of Salmonella enterica serovar Typhimurium LT2.";
RL   Nature 413:852-856(2001).
CC   -!- FUNCTION: Component of the tagatose-1,6-bisphosphate aldolase GatYZ
CC       that is required for full activity and stability of the Y subunit.
CC       Could have a chaperone-like function for the proper and stable folding
CC       of GatY. When expressed alone, GatZ does not show any aldolase
CC       activity. Is involved in the catabolism of galactitol.
CC       {ECO:0000255|HAMAP-Rule:MF_01296}.
CC   -!- PATHWAY: Carbohydrate metabolism; D-tagatose 6-phosphate degradation;
CC       D-glyceraldehyde 3-phosphate and glycerone phosphate from D-tagatose 6-
CC       phosphate: step 2/2. {ECO:0000255|HAMAP-Rule:MF_01296}.
CC   -!- SUBUNIT: Forms a complex with GatY. {ECO:0000255|HAMAP-Rule:MF_01296}.
CC   -!- SIMILARITY: Belongs to the GatZ/KbaZ family. GatZ subfamily.
CC       {ECO:0000255|HAMAP-Rule:MF_01296}.
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DR   EMBL; AE006468; AAL22129.1; -; Genomic_DNA.
DR   RefSeq; NP_462170.1; NC_003197.2.
DR   RefSeq; WP_000658628.1; NC_003197.2.
DR   AlphaFoldDB; Q8ZLV1; -.
DR   SMR; Q8ZLV1; -.
DR   STRING; 99287.STM3257; -.
DR   PaxDb; Q8ZLV1; -.
DR   EnsemblBacteria; AAL22129; AAL22129; STM3257.
DR   GeneID; 1254780; -.
DR   KEGG; stm:STM3257; -.
DR   PATRIC; fig|99287.12.peg.3456; -.
DR   HOGENOM; CLU_053334_0_0_6; -.
DR   OMA; AINAVHV; -.
DR   PhylomeDB; Q8ZLV1; -.
DR   BioCyc; SENT99287:STM3257-MON; -.
DR   UniPathway; UPA00704; UER00716.
DR   Proteomes; UP000001014; Chromosome.
DR   GO; GO:0005887; C:integral component of plasma membrane; IBA:GO_Central.
DR   GO; GO:2001059; P:D-tagatose 6-phosphate catabolic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0019404; P:galactitol catabolic process; IEA:UniProtKB-UniRule.
DR   GO; GO:0009401; P:phosphoenolpyruvate-dependent sugar phosphotransferase system; IBA:GO_Central.
DR   Gene3D; 3.20.20.70; -; 1.
DR   HAMAP; MF_01296; Tagatose_aldol_GatZ; 1.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR012062; GatZ/KbaZ-like.
DR   InterPro; IPR023436; TagBP_ald_GatZ.
DR   Pfam; PF08013; GatZ_KbaZ-like; 1.
DR   PIRSF; PIRSF009264; TagBP_ald_AgaZ; 1.
DR   TIGRFAMs; TIGR02810; agaZ_gatZ; 1.
PE   3: Inferred from homology;
KW   Galactitol metabolism; Reference proteome.
FT   CHAIN           1..423
FT                   /note="D-tagatose-1,6-bisphosphate aldolase subunit GatZ"
FT                   /id="PRO_0000372518"
SQ   SEQUENCE   423 AA;  47190 MW;  822922159D1F24E3 CRC64;
     MKEIIARHKA GEHLGICSVC SAHPLVIESA LLFDLNTDNK VLIEATSNQV NQFGGYTGMK
     PADFRDFVYG IAQEVGFPRE RLILGGDHLG PNCWQNEPAA AAMEKSVELI KAYVAAGFSK
     IHLDASMSCA DDPTPLDPMV VARRAAVLCK AAEGTANEEQ KCHLTYVIGT EVPVPGGEAS
     TIGSVHVTRE VDAARTLETH QIAFRESGLE EALSRVIAIV VQPGVEFDHT QIIHYQPQAA
     QALSAWIKET PMVYEAHSTD YQTRQAYRAL VRDHYAILKV GPALTFALRE AIFALAQMEN
     ELISPEQRSR VLEVIDEVML NEPGYWKKYY RPTWSQAMVD IHFSLSDRIR YYWPHPRIRQ
     SVEKLIANLN NVTLPLGLIS QFMPVQFERL SEGVLTPTPH NLIIDKIQDV LRAYRFGCTP
     DVA