GATZ_SHIB3
ID GATZ_SHIB3 Reviewed; 420 AA.
AC B2TY93;
DT 05-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT 01-JUL-2008, sequence version 1.
DT 03-AUG-2022, entry version 70.
DE RecName: Full=D-tagatose-1,6-bisphosphate aldolase subunit GatZ {ECO:0000255|HAMAP-Rule:MF_01296};
GN Name=gatZ {ECO:0000255|HAMAP-Rule:MF_01296};
GN OrderedLocusNames=SbBS512_E1143;
OS Shigella boydii serotype 18 (strain CDC 3083-94 / BS512).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Shigella.
OX NCBI_TaxID=344609;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CDC 3083-94 / BS512;
RA Rasko D.A., Rosovitz M., Maurelli A.T., Myers G., Seshadri R., Cer R.,
RA Jiang L., Ravel J., Sebastian Y.;
RT "Complete sequence of Shigella boydii serotype 18 strain BS512.";
RL Submitted (MAY-2008) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Component of the tagatose-1,6-bisphosphate aldolase GatYZ
CC that is required for full activity and stability of the Y subunit.
CC Could have a chaperone-like function for the proper and stable folding
CC of GatY. When expressed alone, GatZ does not show any aldolase
CC activity. Is involved in the catabolism of galactitol.
CC {ECO:0000255|HAMAP-Rule:MF_01296}.
CC -!- PATHWAY: Carbohydrate metabolism; D-tagatose 6-phosphate degradation;
CC D-glyceraldehyde 3-phosphate and glycerone phosphate from D-tagatose 6-
CC phosphate: step 2/2. {ECO:0000255|HAMAP-Rule:MF_01296}.
CC -!- SUBUNIT: Forms a complex with GatY. {ECO:0000255|HAMAP-Rule:MF_01296}.
CC -!- SIMILARITY: Belongs to the GatZ/KbaZ family. GatZ subfamily.
CC {ECO:0000255|HAMAP-Rule:MF_01296}.
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DR EMBL; CP001063; ACD08220.1; -; Genomic_DNA.
DR RefSeq; WP_000853861.1; NC_010658.1.
DR AlphaFoldDB; B2TY93; -.
DR SMR; B2TY93; -.
DR STRING; 344609.SbBS512_E1143; -.
DR EnsemblBacteria; ACD08220; ACD08220; SbBS512_E1143.
DR KEGG; sbc:SbBS512_E1143; -.
DR HOGENOM; CLU_053334_0_0_6; -.
DR OMA; AINAVHV; -.
DR UniPathway; UPA00704; UER00716.
DR Proteomes; UP000001030; Chromosome.
DR GO; GO:2001059; P:D-tagatose 6-phosphate catabolic process; IEA:UniProtKB-UniPathway.
DR GO; GO:0019404; P:galactitol catabolic process; IEA:UniProtKB-UniRule.
DR Gene3D; 3.20.20.70; -; 1.
DR HAMAP; MF_01296; Tagatose_aldol_GatZ; 1.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR012062; GatZ/KbaZ-like.
DR InterPro; IPR023436; TagBP_ald_GatZ.
DR Pfam; PF08013; GatZ_KbaZ-like; 1.
DR PIRSF; PIRSF009264; TagBP_ald_AgaZ; 1.
DR TIGRFAMs; TIGR02810; agaZ_gatZ; 1.
PE 3: Inferred from homology;
KW Galactitol metabolism.
FT CHAIN 1..420
FT /note="D-tagatose-1,6-bisphosphate aldolase subunit GatZ"
FT /id="PRO_0000372519"
SQ SEQUENCE 420 AA; 47025 MW; 724AE97190E8849C CRC64;
MKTLIARHKA GEHIGICSVC SAHPLVIEAA LAFDRNSTRK VLIEATSNQV NQFGGYTGMT
PADFREFVFT IADKVGFARE RIILGGDHLG PNCWQQENAD AAMEKSVELV KAYVRAGFSK
IHLDASMSCA GDPIPLAPET VAERAAVLCF AAESVATDCQ REQLSYVIGT EVPVPGGEAS
AIQSVHITHV EDAANTLRTH QKAFIARGLT EALTRVIAIV VQPGVEFDHS NIIHYQPQEA
QALAQWIENT RMVYEAHSTD YQTRTAYWEL VRDHFAILKV GPALTFALRE AIFALAQIEQ
ELIAPENRSG CLAVIEEVML DEPQYWKKYY RTGFNDSLLD IRYSLSDRIR YYWPHSRIKN
SVETMMVNLE GVDIPLGMIS QYLPKQFERI QSGELSAIPH QLIMDKIYDV LRAYRYGCAE