ID   GATZ_SHIF8              Reviewed;         420 AA.
AC   Q0T343;
DT   05-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT   05-SEP-2006, sequence version 1.
DT   03-AUG-2022, entry version 88.
DE   RecName: Full=D-tagatose-1,6-bisphosphate aldolase subunit GatZ {ECO:0000255|HAMAP-Rule:MF_01296};
GN   Name=gatZ {ECO:0000255|HAMAP-Rule:MF_01296}; OrderedLocusNames=SFV_2150;
OS   Shigella flexneri serotype 5b (strain 8401).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Shigella.
OX   NCBI_TaxID=373384;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=8401;
RX   PubMed=16822325; DOI=10.1186/1471-2164-7-173;
RA   Nie H., Yang F., Zhang X., Yang J., Chen L., Wang J., Xiong Z., Peng J.,
RA   Sun L., Dong J., Xue Y., Xu X., Chen S., Yao Z., Shen Y., Jin Q.;
RT   "Complete genome sequence of Shigella flexneri 5b and comparison with
RT   Shigella flexneri 2a.";
RL   BMC Genomics 7:173-173(2006).
CC   -!- FUNCTION: Component of the tagatose-1,6-bisphosphate aldolase GatYZ
CC       that is required for full activity and stability of the Y subunit.
CC       Could have a chaperone-like function for the proper and stable folding
CC       of GatY. When expressed alone, GatZ does not show any aldolase
CC       activity. Is involved in the catabolism of galactitol.
CC       {ECO:0000255|HAMAP-Rule:MF_01296}.
CC   -!- PATHWAY: Carbohydrate metabolism; D-tagatose 6-phosphate degradation;
CC       D-glyceraldehyde 3-phosphate and glycerone phosphate from D-tagatose 6-
CC       phosphate: step 2/2. {ECO:0000255|HAMAP-Rule:MF_01296}.
CC   -!- SUBUNIT: Forms a complex with GatY. {ECO:0000255|HAMAP-Rule:MF_01296}.
CC   -!- SIMILARITY: Belongs to the GatZ/KbaZ family. GatZ subfamily.
CC       {ECO:0000255|HAMAP-Rule:MF_01296}.
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DR   EMBL; CP000266; ABF04272.1; -; Genomic_DNA.
DR   RefSeq; WP_000853873.1; NC_008258.1.
DR   AlphaFoldDB; Q0T343; -.
DR   SMR; Q0T343; -.
DR   EnsemblBacteria; ABF04272; ABF04272; SFV_2150.
DR   GeneID; 58389580; -.
DR   KEGG; sfv:SFV_2150; -.
DR   HOGENOM; CLU_053334_0_0_6; -.
DR   OMA; AINAVHV; -.
DR   BioCyc; SFLE373384:SFV_RS12055-MON; -.
DR   UniPathway; UPA00704; UER00716.
DR   Proteomes; UP000000659; Chromosome.
DR   GO; GO:2001059; P:D-tagatose 6-phosphate catabolic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0019404; P:galactitol catabolic process; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.20.20.70; -; 1.
DR   HAMAP; MF_01296; Tagatose_aldol_GatZ; 1.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR012062; GatZ/KbaZ-like.
DR   InterPro; IPR023436; TagBP_ald_GatZ.
DR   Pfam; PF08013; GatZ_KbaZ-like; 1.
DR   PIRSF; PIRSF009264; TagBP_ald_AgaZ; 1.
DR   TIGRFAMs; TIGR02810; agaZ_gatZ; 1.
PE   3: Inferred from homology;
KW   Galactitol metabolism.
FT   CHAIN           1..420
FT                   /note="D-tagatose-1,6-bisphosphate aldolase subunit GatZ"
FT                   /id="PRO_0000372521"
SQ   SEQUENCE   420 AA;  47045 MW;  2C2D83C4A2E0D7F8 CRC64;
     MKTLIARHKA GEHIGICSVC SAHPLVIEAA LAFDRNSTRK VLIEATSNQV NQFGGYTGMT
     PADFREFVFT IADKVGFARE RIILGGDHLG PNCWQQENAD AAMEKSVELV KAYVRAGFSK
     IHLDASMSCA GDTIPLAPET VAERAAVLCF AAESVATDCQ REQLSYVIGT EVPVPGGEAS
     AIQSVHITHV EDAANTLRTH QKAFIARGLT EALTRVIAIV VQPGVEFDHS NIIHYQPQEA
     QALAQWIENT RMVYEAHSTD YQTRTAYWEL VRDHFAILKV GPALTFALRE AIFALAQIEQ
     ELIAPENRSG CLAVIEEVML DEPQYWKKYY RTGFNDSLLD IRYSLSDRIR YYWPHSRIKN
     SVETMMVNLQ GVDIPLGMIS QYLPKQFERI QSGELSAMPH QLIMNKIYDV LRAYRYGCAE