ID   GBB1_DANRE              Reviewed;         340 AA.
AC   Q6PH57;
DT   16-AUG-2004, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 116.
DE   RecName: Full=Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1;
DE   AltName: Full=Transducin beta chain 1;
GN   Name=gnb1;
OS   Danio rerio (Zebrafish) (Brachydanio rerio).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Danionidae; Danioninae; Danio.
OX   NCBI_TaxID=7955;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Embryo, and Kidney;
RG   NIH - Zebrafish Gene Collection (ZGC) project;
RL   Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Guanine nucleotide-binding proteins (G proteins) are involved
CC       as a modulator or transducer in various transmembrane signaling
CC       systems. The beta and gamma chains are required for the GTPase
CC       activity, for replacement of GDP by GTP, and for G protein-effector
CC       interaction (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: G proteins are composed of 3 units, alpha, beta and gamma.
CC   -!- SIMILARITY: Belongs to the WD repeat G protein beta family.
CC       {ECO:0000305}.
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DR   EMBL; BC056708; AAH56708.1; -; mRNA.
DR   EMBL; BC071277; AAH71277.1; -; mRNA.
DR   RefSeq; NP_997774.1; NM_212609.1.
DR   AlphaFoldDB; Q6PH57; -.
DR   SMR; Q6PH57; -.
DR   STRING; 7955.ENSDARP00000111963; -.
DR   PaxDb; Q6PH57; -.
DR   Ensembl; ENSDART00000130104; ENSDARP00000111963; ENSDARG00000090454.
DR   Ensembl; ENSDART00000184212; ENSDARP00000150406; ENSDARG00000090454.
DR   GeneID; 322104; -.
DR   KEGG; dre:322104; -.
DR   CTD; 322104; -.
DR   ZFIN; ZDB-GENE-030131-823; gnb1a.
DR   eggNOG; KOG0286; Eukaryota.
DR   GeneTree; ENSGT01000000214413; -.
DR   HOGENOM; CLU_000288_57_34_1; -.
DR   InParanoid; Q6PH57; -.
DR   OMA; QSKTFVS; -.
DR   OrthoDB; 704786at2759; -.
DR   PhylomeDB; Q6PH57; -.
DR   TreeFam; TF106149; -.
DR   PRO; PR:Q6PH57; -.
DR   Proteomes; UP000000437; Genome assembly.
DR   Proteomes; UP000814640; Chromosome 8.
DR   Bgee; ENSDARG00000090454; Expressed in zone of skin and 44 other tissues.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0005834; C:heterotrimeric G-protein complex; IBA:GO_Central.
DR   GO; GO:0030159; F:signaling receptor complex adaptor activity; IBA:GO_Central.
DR   GO; GO:0007186; P:G protein-coupled receptor signaling pathway; IBA:GO_Central.
DR   GO; GO:1902624; P:positive regulation of neutrophil migration; IGI:ZFIN.
DR   GO; GO:0048920; P:posterior lateral line neuromast primordium migration; IGI:ZFIN.
DR   Gene3D; 2.130.10.10; -; 1.
DR   InterPro; IPR020472; G-protein_beta_WD-40_rep.
DR   InterPro; IPR001632; Gprotein_B.
DR   InterPro; IPR016346; Guanine_nucleotide-bd_bsu.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR001680; WD40_repeat.
DR   InterPro; IPR019775; WD40_repeat_CS.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   PANTHER; PTHR19850; PTHR19850; 1.
DR   Pfam; PF00400; WD40; 7.
DR   PRINTS; PR00319; GPROTEINB.
DR   PRINTS; PR00320; GPROTEINBRPT.
DR   SMART; SM00320; WD40; 7.
DR   SUPFAM; SSF50978; SSF50978; 1.
DR   PROSITE; PS00678; WD_REPEATS_1; 3.
DR   PROSITE; PS50082; WD_REPEATS_2; 6.
DR   PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE   2: Evidence at transcript level;
KW   Reference proteome; Repeat; Transducer; WD repeat.
FT   CHAIN           1..340
FT                   /note="Guanine nucleotide-binding protein G(I)/G(S)/G(T)
FT                   subunit beta-1"
FT                   /id="PRO_0000127691"
FT   REPEAT          53..83
FT                   /note="WD 1"
FT   REPEAT          95..125
FT                   /note="WD 2"
FT   REPEAT          141..170
FT                   /note="WD 3"
FT   REPEAT          182..212
FT                   /note="WD 4"
FT   REPEAT          224..254
FT                   /note="WD 5"
FT   REPEAT          268..298
FT                   /note="WD 6"
FT   REPEAT          310..340
FT                   /note="WD 7"
SQ   SEQUENCE   340 AA;  37286 MW;  03EB4B3AAD3AA209 CRC64;
     MSELDQLRQE AEQLKNQIRD ARKACADATL SQITANIDPV GRIQMRTRRT LRGHLAKIYA
     MHWGTDSRLL VSASQDGKLI IWDSYTTNKV HAIPLRSSWV MTCAYAPSGN YVACGGLDNI
     CSIYNLKTRE GNVRVSRELA GHTGYLSCCR FLDDNQIVTS SGDTTCALWD IETGQQTTTF
     AGHTGDVMSL SLAPDTRLFV SGACDASAKL WDVREGMCRQ TFTGHESDIN AICFFPNGNA
     FATGSDDATC RLFDLRADQE LMVYSHDNII CGITSVAFSK SGRLLLAGYD DFNCNVWDAL
     KADRAGVLAG HDNRVSCLGV TDDGMAVATG SWDSFLKIWN