ID   GBB1_HOMAM              Reviewed;         340 AA.
AC   O45040;
DT   15-DEC-1998, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-1998, sequence version 1.
DT   25-MAY-2022, entry version 78.
DE   RecName: Full=Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1;
DE   AltName: Full=Transducin beta chain 1;
GN   Name=GBETA1;
OS   Homarus americanus (American lobster).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Crustacea; Multicrustacea;
OC   Malacostraca; Eumalacostraca; Eucarida; Decapoda; Pleocyemata; Astacidea;
OC   Nephropoidea; Nephropidae; Homarus.
OX   NCBI_TaxID=6706;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RX   PubMed=9740024;
RX   DOI=10.1002/(sici)1097-4695(19980915)36:4<525::aid-neu6>3.0.co;2-y;
RA   Xu F., Hollins B., Landers T.M., McClintock T.S.;
RT   "Molecular cloning of a lobster Gbeta subunit and Gbeta expression in
RT   olfactory receptor neuron dendrites and brain neuropil.";
RL   J. Neurobiol. 36:525-536(1998).
CC   -!- FUNCTION: Guanine nucleotide-binding proteins (G proteins) are involved
CC       as a modulator or transducer in various transmembrane signaling
CC       systems. The beta and gamma chains are required for the GTPase
CC       activity, for replacement of GDP by GTP, and for G protein-effector
CC       interaction.
CC   -!- SUBUNIT: G proteins are composed of 3 units, alpha, beta and gamma.
CC   -!- SIMILARITY: Belongs to the WD repeat G protein beta family.
CC       {ECO:0000305}.
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DR   EMBL; AF044735; AAC02998.1; -; mRNA.
DR   AlphaFoldDB; O45040; -.
DR   SMR; O45040; -.
DR   GO; GO:0007165; P:signal transduction; IEA:UniProtKB-KW.
DR   Gene3D; 2.130.10.10; -; 1.
DR   InterPro; IPR020472; G-protein_beta_WD-40_rep.
DR   InterPro; IPR001632; Gprotein_B.
DR   InterPro; IPR016346; Guanine_nucleotide-bd_bsu.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR001680; WD40_repeat.
DR   InterPro; IPR019775; WD40_repeat_CS.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   PANTHER; PTHR19850; PTHR19850; 1.
DR   Pfam; PF00400; WD40; 6.
DR   PRINTS; PR00319; GPROTEINB.
DR   PRINTS; PR00320; GPROTEINBRPT.
DR   SMART; SM00320; WD40; 7.
DR   SUPFAM; SSF50978; SSF50978; 1.
DR   PROSITE; PS00678; WD_REPEATS_1; 3.
DR   PROSITE; PS50082; WD_REPEATS_2; 6.
DR   PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE   2: Evidence at transcript level;
KW   Repeat; Transducer; WD repeat.
FT   CHAIN           1..340
FT                   /note="Guanine nucleotide-binding protein G(I)/G(S)/G(T)
FT                   subunit beta-1"
FT                   /id="PRO_0000127693"
FT   REPEAT          53..83
FT                   /note="WD 1"
FT   REPEAT          95..125
FT                   /note="WD 2"
FT   REPEAT          141..170
FT                   /note="WD 3"
FT   REPEAT          182..212
FT                   /note="WD 4"
FT   REPEAT          224..254
FT                   /note="WD 5"
FT   REPEAT          268..298
FT                   /note="WD 6"
FT   REPEAT          310..340
FT                   /note="WD 7"
SQ   SEQUENCE   340 AA;  37409 MW;  3483245F9291D82E CRC64;
     MNDLDSLRQE AERLKNTIRD ARKNALDTTL VQATAGMDPI GRIQMRTRRT LRGHLAKIYA
     MHWGSDSRNL VSASQDGKLI VWDSYTTNKV HAIPLRSSWV MTCAYAPSGS YVACGGLDNI
     CSIYSLKTRE GNVRVSRELP GHTGYLSCCR FVDDNQIVTS SGDMTCALWD IETGQQCTQF
     TGHTGDVMSL SLSPNMRTFT SGACDASAKL WDIRDGMCRQ TFPGHESDIN AVTFFPNGHA
     FATGSDDATC RLFDIRADQE LAMYSHDNII CGITSVAFSK SGKLLLAGYD DFNCNVWDSM
     RTERAGVLAG HDNRVSCLGV TEDGMAVATG SWDSFLKIWN