ID   GBB2_TOBAC              Reviewed;         377 AA.
AC   P93398;
DT   15-JUL-1998, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-1997, sequence version 1.
DT   25-MAY-2022, entry version 92.
DE   RecName: Full=Guanine nucleotide-binding protein subunit beta-2;
OS   Nicotiana tabacum (Common tobacco).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae;
OC   Nicotiana.
OX   NCBI_TaxID=4097;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   STRAIN=cv. SR1; TISSUE=Leaf;
RA   Lein W., Saalbach G.;
RL   Submitted (FEB-1997) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Guanine nucleotide-binding proteins (G proteins) are involved
CC       as a modulator or transducer in various transmembrane signaling
CC       systems. The beta and gamma chains are required for the GTPase
CC       activity, for replacement of GDP by GTP, and for G protein-effector
CC       interaction.
CC   -!- SUBUNIT: G proteins are composed of 3 units, alpha, beta and gamma.
CC   -!- SIMILARITY: Belongs to the WD repeat G protein beta family.
CC       {ECO:0000305}.
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DR   EMBL; Z84821; CAB06619.1; -; mRNA.
DR   PIR; T04089; T04089.
DR   RefSeq; NP_001311627.1; NM_001324698.1.
DR   AlphaFoldDB; P93398; -.
DR   SMR; P93398; -.
DR   STRING; 4097.P93398; -.
DR   GeneID; 107760597; -.
DR   KEGG; nta:107760597; -.
DR   OMA; GDTNCAL; -.
DR   PhylomeDB; P93398; -.
DR   Proteomes; UP000084051; Unplaced.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0005834; C:heterotrimeric G-protein complex; IBA:GO_Central.
DR   GO; GO:0030159; F:signaling receptor complex adaptor activity; IBA:GO_Central.
DR   GO; GO:0007186; P:G protein-coupled receptor signaling pathway; IBA:GO_Central.
DR   Gene3D; 2.130.10.10; -; 1.
DR   InterPro; IPR020472; G-protein_beta_WD-40_rep.
DR   InterPro; IPR001632; Gprotein_B.
DR   InterPro; IPR016346; Guanine_nucleotide-bd_bsu.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR001680; WD40_repeat.
DR   InterPro; IPR019775; WD40_repeat_CS.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   PANTHER; PTHR19850; PTHR19850; 1.
DR   Pfam; PF00400; WD40; 7.
DR   PRINTS; PR00319; GPROTEINB.
DR   PRINTS; PR00320; GPROTEINBRPT.
DR   SMART; SM00320; WD40; 7.
DR   SUPFAM; SSF50978; SSF50978; 1.
DR   PROSITE; PS00678; WD_REPEATS_1; 2.
DR   PROSITE; PS50082; WD_REPEATS_2; 5.
DR   PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE   2: Evidence at transcript level;
KW   Reference proteome; Repeat; Transducer; WD repeat.
FT   CHAIN           1..377
FT                   /note="Guanine nucleotide-binding protein subunit beta-2"
FT                   /id="PRO_0000127728"
FT   REPEAT          63..93
FT                   /note="WD 1"
FT   REPEAT          105..135
FT                   /note="WD 2"
FT   REPEAT          154..185
FT                   /note="WD 3"
FT   REPEAT          202..233
FT                   /note="WD 4"
FT   REPEAT          246..276
FT                   /note="WD 5"
FT   REPEAT          293..323
FT                   /note="WD 6"
FT   REPEAT          339..369
FT                   /note="WD 7"
SQ   SEQUENCE   377 AA;  41084 MW;  2EF2EB44272D3472 CRC64;
     MSVKELKERH MAATQTVNDL REKLKQKRLQ LLDTDVSGYA RSQGKTPVIF GPTDLVCCRI
     LQGHTGKVYS LDWTPEKNRI VSASQDGRLI VWNALTSQKT HAIKLPCAWV MTCAFSPSGQ
     SVACGGLDSV CSIFNLNSPI DKDGNHPVSR MLSGHKGYVS SCQYVPDEDT HVITSSGDQT
     CVLWDITTGL RTSVFGGEFQ SGHTADVQSV SISSSNPRLF VSGSCDSTAR LWDTRVASRA
     QRTFYGHEGD VNTVKFFPDG NRFGTGSDDG TCRLFDIRTG HQLQVYYQPH GDGDIPHVTS
     MAFSISGRLL FVGYSNGDCY VWDTLLAKVV LNLGAVQNSH EGRISCLGLS ADGSALCTGS
     WDTNLKIWAF GGHRSVI