ID   GBB3_TOBAC              Reviewed;         375 AA.
AC   Q40507;
DT   15-JUL-1998, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   25-MAY-2022, entry version 93.
DE   RecName: Full=Guanine nucleotide-binding protein subunit beta;
OS   Nicotiana tabacum (Common tobacco).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae;
OC   Nicotiana.
OX   NCBI_TaxID=4097;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   STRAIN=cv. Samsun NN; TISSUE=Leaf;
RA   Kusnetsov V.V., Oelmueller R.;
RT   "Isolation and characterization of cDNAs encoding the subunit beta of
RT   heterotrimeric G proteins from N. tabacum.";
RL   (er) Plant Gene Register PGR96-048(1996).
CC   -!- FUNCTION: Guanine nucleotide-binding proteins (G proteins) are involved
CC       as a modulator or transducer in various transmembrane signaling
CC       systems. The beta and gamma chains are required for the GTPase
CC       activity, for replacement of GDP by GTP, and for G protein-effector
CC       interaction.
CC   -!- SUBUNIT: G proteins are composed of 3 units, alpha, beta and gamma.
CC   -!- SIMILARITY: Belongs to the WD repeat G protein beta family.
CC       {ECO:0000305}.
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DR   EMBL; X98161; CAA66842.1; -; mRNA.
DR   PIR; T03256; T03256.
DR   AlphaFoldDB; Q40507; -.
DR   SMR; Q40507; -.
DR   STRING; 4097.Q40507; -.
DR   Proteomes; UP000084051; Unplaced.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0005834; C:heterotrimeric G-protein complex; IBA:GO_Central.
DR   GO; GO:0030159; F:signaling receptor complex adaptor activity; IBA:GO_Central.
DR   GO; GO:0007186; P:G protein-coupled receptor signaling pathway; IBA:GO_Central.
DR   Gene3D; 2.130.10.10; -; 1.
DR   InterPro; IPR020472; G-protein_beta_WD-40_rep.
DR   InterPro; IPR001632; Gprotein_B.
DR   InterPro; IPR016346; Guanine_nucleotide-bd_bsu.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR001680; WD40_repeat.
DR   InterPro; IPR019775; WD40_repeat_CS.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   PANTHER; PTHR19850; PTHR19850; 1.
DR   Pfam; PF00400; WD40; 7.
DR   PRINTS; PR00319; GPROTEINB.
DR   PRINTS; PR00320; GPROTEINBRPT.
DR   SMART; SM00320; WD40; 7.
DR   SUPFAM; SSF50978; SSF50978; 1.
DR   PROSITE; PS00678; WD_REPEATS_1; 2.
DR   PROSITE; PS50082; WD_REPEATS_2; 5.
DR   PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE   2: Evidence at transcript level;
KW   Reference proteome; Repeat; Transducer; WD repeat.
FT   CHAIN           1..375
FT                   /note="Guanine nucleotide-binding protein subunit beta"
FT                   /id="PRO_0000127729"
FT   REPEAT          63..93
FT                   /note="WD 1"
FT   REPEAT          105..135
FT                   /note="WD 2"
FT   REPEAT          154..185
FT                   /note="WD 3"
FT   REPEAT          202..233
FT                   /note="WD 4"
FT   REPEAT          246..276
FT                   /note="WD 5"
FT   REPEAT          293..323
FT                   /note="WD 6"
FT   REPEAT          339..369
FT                   /note="WD 7"
SQ   SEQUENCE   375 AA;  40812 MW;  72D53D1DFC5CF598 CRC64;
     MSVTELKERH MAATQTVSDL REKLKQKRLQ LLDTDVSGYA RSQGKTPVTF GPTDLVCCRI
     LQGHTGKVYS LDWTPEKNRI VSASQDGRLI VWNALTSQKT HAIKLPCAWV MTCAFSPSGQ
     SVACGGLDSV CSIYNLNSPI DKDGNHPVSR MLSGHKGYVS SCQYVPDEDT HLITSSGDQT
     CVLWDITTGL RTSVFGGEFQ SGHTADVQSV SISSSNPRLF VSGSCDTTAR LWDNRVASRA
     QRTFYGHEGD VNTVKFFPDG NRFGTGSEDG TCRLFDIRTG HQLQVYYQPH GDGDIPHVTS
     MAFSISGRLL FVGYSNGDCY VWDTLLAKVV LNLGGVQNSH EGRISCLGLS ADGSALCTGS
     WDTNLKIWAF GGTEV