ID   GBB_LYMST               Reviewed;         341 AA.
AC   Q08706;
DT   01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1996, sequence version 1.
DT   25-MAY-2022, entry version 86.
DE   RecName: Full=Guanine nucleotide-binding protein subunit beta;
OS   Lymnaea stagnalis (Great pond snail) (Helix stagnalis).
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Gastropoda;
OC   Heterobranchia; Euthyneura; Panpulmonata; Hygrophila; Lymnaeoidea;
OC   Lymnaeidae; Lymnaea.
OX   NCBI_TaxID=6523;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   TISSUE=CNS;
RX   PubMed=7514444; DOI=10.1016/0167-4889(94)90035-3;
RA   Knol J.C., Roovers E., van Kesteren E.R., Planta R.J., Vreugdenhil R.,
RA   van Heerikhuizen H.;
RT   "A G-protein beta subunit that is expressed in the central nervous system
RT   of the mollusc Lymnaea stagnalis identified through cDNA cloning.";
RL   Biochim. Biophys. Acta 1222:129-133(1994).
CC   -!- FUNCTION: Guanine nucleotide-binding proteins (G proteins) are involved
CC       as a modulator or transducer in various transmembrane signaling
CC       systems. The beta and gamma chains are required for the GTPase
CC       activity, for replacement of GDP by GTP, and for G protein-effector
CC       interaction.
CC   -!- SUBUNIT: G proteins are composed of 3 units, alpha, beta and gamma.
CC   -!- SIMILARITY: Belongs to the WD repeat G protein beta family.
CC       {ECO:0000305}.
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DR   EMBL; Z23105; CAA80652.1; -; mRNA.
DR   PIR; S69891; S34348.
DR   AlphaFoldDB; Q08706; -.
DR   SMR; Q08706; -.
DR   GO; GO:0007165; P:signal transduction; IEA:UniProtKB-KW.
DR   Gene3D; 2.130.10.10; -; 1.
DR   InterPro; IPR020472; G-protein_beta_WD-40_rep.
DR   InterPro; IPR001632; Gprotein_B.
DR   InterPro; IPR016346; Guanine_nucleotide-bd_bsu.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR001680; WD40_repeat.
DR   InterPro; IPR019775; WD40_repeat_CS.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   PANTHER; PTHR19850; PTHR19850; 1.
DR   Pfam; PF00400; WD40; 7.
DR   PRINTS; PR00319; GPROTEINB.
DR   PRINTS; PR00320; GPROTEINBRPT.
DR   SMART; SM00320; WD40; 7.
DR   SUPFAM; SSF50978; SSF50978; 1.
DR   PROSITE; PS00678; WD_REPEATS_1; 2.
DR   PROSITE; PS50082; WD_REPEATS_2; 5.
DR   PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE   2: Evidence at transcript level;
KW   Repeat; Transducer; WD repeat.
FT   CHAIN           1..341
FT                   /note="Guanine nucleotide-binding protein subunit beta"
FT                   /id="PRO_0000127718"
FT   REPEAT          54..84
FT                   /note="WD 1"
FT   REPEAT          96..126
FT                   /note="WD 2"
FT   REPEAT          142..171
FT                   /note="WD 3"
FT   REPEAT          183..213
FT                   /note="WD 4"
FT   REPEAT          225..255
FT                   /note="WD 5"
FT   REPEAT          269..299
FT                   /note="WD 6"
FT   REPEAT          311..341
FT                   /note="WD 7"
SQ   SEQUENCE   341 AA;  37321 MW;  4A2662588387592E CRC64;
     MSNDLEALRQ ETEQLKNQIR EARKAAGDTT LAQACSGVEA VGRIQMRTRR TLRGHLAKIY
     AMHWASDSRN LVSASQDGKL IVWDGYTTNK VHAIPLRSSW VMTCAYAPSG NFVACGGLDN
     ICSIYSLKTR EGNVRVSREL PGHTGYLSCC RFIDDNSIVT SSGDMSCALW DIETGQQTTS
     FTGHTGDVMS LSTSPDFRTF VSGACDASAK LWDVRDGMCK QTFSGHESDI NAITYFPNGH
     AFATGSDDAT CRLFDIRADQ EIGMYSHDNI ICGITSVAFS KSGRLLLGRY DDFNCNVWDV
     LKQETHGVLA GHDNRVSCLG VTEDGSAVAT GSWDSFLKIW N