ID   GBB_NICPL               Reviewed;         377 AA.
AC   P93339;
DT   15-JUL-1998, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-1997, sequence version 1.
DT   29-SEP-2021, entry version 100.
DE   RecName: Full=Guanine nucleotide-binding protein subunit beta;
DE   AltName: Full=NpGPB1;
OS   Nicotiana plumbaginifolia (Leadwort-leaved tobacco) (Tex-Mex tobacco).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae;
OC   Nicotiana.
OX   NCBI_TaxID=4092;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RX   PubMed=10760577; DOI=10.1016/s0167-4781(00)00039-7;
RA   Kaydamov C., Tewes A., Adler K., Manteuffel R.;
RT   "Molecular characterization of cDNAs encoding G protein alpha and beta
RT   subunits and study of their temporal and spatial expression patterns in
RT   Nicotiana plumbaginifolia Viv.";
RL   Biochim. Biophys. Acta 1491:143-160(2000).
CC   -!- FUNCTION: Guanine nucleotide-binding proteins (G proteins) are involved
CC       as a modulator or transducer in various transmembrane signaling
CC       systems. The beta and gamma chains are required for the GTPase
CC       activity, for replacement of GDP by GTP, and for G protein-effector
CC       interaction.
CC   -!- SUBUNIT: G proteins are composed of 3 units, alpha, beta and gamma.
CC   -!- SUBCELLULAR LOCATION: Cell membrane. Endoplasmic reticulum membrane.
CC   -!- INDUCTION: By auxin.
CC   -!- SIMILARITY: Belongs to the WD repeat G protein beta family.
CC       {ECO:0000305}.
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DR   EMBL; Y09513; CAA70704.1; -; mRNA.
DR   PIR; T16985; T16985.
DR   GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0007165; P:signal transduction; IEA:UniProtKB-KW.
DR   Gene3D; 2.130.10.10; -; 1.
DR   InterPro; IPR020472; G-protein_beta_WD-40_rep.
DR   InterPro; IPR001632; Gprotein_B.
DR   InterPro; IPR016346; Guanine_nucleotide-bd_bsu.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR001680; WD40_repeat.
DR   InterPro; IPR019775; WD40_repeat_CS.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   PANTHER; PTHR19850; PTHR19850; 1.
DR   Pfam; PF00400; WD40; 5.
DR   PRINTS; PR00319; GPROTEINB.
DR   PRINTS; PR00320; GPROTEINBRPT.
DR   SMART; SM00320; WD40; 7.
DR   SUPFAM; SSF50978; SSF50978; 1.
DR   PROSITE; PS00678; WD_REPEATS_1; 2.
DR   PROSITE; PS50082; WD_REPEATS_2; 5.
DR   PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE   2: Evidence at transcript level;
KW   Cell membrane; Endoplasmic reticulum; Membrane; Repeat; Transducer;
KW   WD repeat.
FT   CHAIN           1..377
FT                   /note="Guanine nucleotide-binding protein subunit beta"
FT                   /id="PRO_0000127724"
FT   REPEAT          63..93
FT                   /note="WD 1"
FT   REPEAT          105..135
FT                   /note="WD 2"
FT   REPEAT          154..185
FT                   /note="WD 3"
FT   REPEAT          202..233
FT                   /note="WD 4"
FT   REPEAT          246..276
FT                   /note="WD 5"
FT   REPEAT          293..323
FT                   /note="WD 6"
FT   REPEAT          339..369
FT                   /note="WD 7"
SQ   SEQUENCE   377 AA;  41321 MW;  0351A96C73B511C5 CRC64;
     MSVTELKERH MAATQTVNDL REKLKQKRLQ LLDTDVSGYA RSQGKTPVTF GPTDLVCCRI
     LQGHTGKVYS LDWTPEKNRI VSASQDGRLI VWNALTSQKT HAIKLPCAWV MTCAFSPSGH
     SVACGGLDSV CSIFNLNSPI DKDGNHPVSR MLSGHKGYVS SCQYVPDEDT HLITSSGDQT
     CVLWDITTGL RTSVFGGEFQ FGHTADVQSV SISSSNPRLF VSGSCDTTAR LWDTRVASRA
     QRTFYCHEGD VNTVKFFPDG NRFGTGSEDG TCRLFDIRTG HQLQVYYQPH GDGDIPHVTS
     MAFSISGRLL FVRYSNGDCY VWDTLLAKVV LNLGAVQNSH EGXISCLGLS ADGXXLCTGS
     WDTNLKIWAF GGHRSVI