ID   ALLA1_DELRA             Reviewed;           8 AA.
AC   B3EWI2;
DT   03-OCT-2012, integrated into UniProtKB/Swiss-Prot.
DT   03-OCT-2012, sequence version 1.
DT   02-JUN-2021, entry version 9.
DE   RecName: Full=Allatostatin-A1;
DE            Short=AST-A1;
DE   AltName: Full=ARPYSFGL-amide;
OS   Delia radicum (Cabbage root fly) (Anthomyia brassicae).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Muscoidea;
OC   Anthomyiidae; Anthomyiinae; Delia.
OX   NCBI_TaxID=30064;
RN   [1] {ECO:0000305}
RP   PROTEIN SEQUENCE, TISSUE SPECIFICITY, MASS SPECTROMETRY, AND AMIDATION AT
RP   LEU-8.
RC   TISSUE=Abdominal ganglion {ECO:0000269|PubMed:20869420},
RC   Brain {ECO:0000269|PubMed:20869420},
RC   Corpora allata {ECO:0000269|PubMed:20869420}, and
RC   Corpora cardiaca {ECO:0000269|PubMed:20869420};
RX   PubMed=20869420; DOI=10.1016/j.peptides.2010.08.028;
RA   Audsley N., Matthews H.J., Down R.E., Weaver R.J.;
RT   "Neuropeptides associated with the central nervous system of the cabbage
RT   root fly, Delia radicum (L).";
RL   Peptides 32:434-440(2011).
RN   [2] {ECO:0000305}
RP   PROTEIN SEQUENCE, TISSUE SPECIFICITY, DEVELOPMENTAL STAGE, MASS
RP   SPECTROMETRY, AND AMIDATION AT LEU-8.
RC   TISSUE=CNS {ECO:0000269|PubMed:22848525};
RX   PubMed=22848525; DOI=10.1371/journal.pone.0041543;
RA   Zoephel J., Reiher W., Rexer K.-H., Kahnt J., Wegener C.;
RT   "Peptidomics of the agriculturally damaging larval stage of the cabbage
RT   root fly Delia radicum (Diptera: Anthomyiidae).";
RL   PLoS ONE 7:E41543-E41543(2012).
CC   -!- FUNCTION: May act as a neurotransmitter or neuromodulator.
CC       {ECO:0000250|UniProtKB:O44314}.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250|UniProtKB:P82155}.
CC   -!- TISSUE SPECIFICITY: In larvae, expressed in the CNS and midgut but not
CC       in the ring gland, thoracic perisymapthetic organs (tPSO) or abdominal
CC       perisymapthetic organs (aPSO) (at protein level). In adults, expressed
CC       in the corpora cardiaca, corpora allata, brain and the thoracic-
CC       abdominal ganglion (at protein level). {ECO:0000269|PubMed:20869420,
CC       ECO:0000269|PubMed:22848525}.
CC   -!- DEVELOPMENTAL STAGE: Detected in larvae and adults.
CC       {ECO:0000269|PubMed:20869420, ECO:0000269|PubMed:22848525}.
CC   -!- MASS SPECTROMETRY: Mass=909.5; Method=MALDI;
CC       Evidence={ECO:0000269|PubMed:20869420, ECO:0000269|PubMed:22848525};
CC   -!- SIMILARITY: Belongs to the allatostatin family. {ECO:0000255}.
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DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0007218; P:neuropeptide signaling pathway; IEA:UniProtKB-KW.
PE   1: Evidence at protein level;
KW   Amidation; Direct protein sequencing; Neuropeptide; Secreted.
FT   PEPTIDE         1..8
FT                   /note="Allatostatin-A1"
FT                   /id="PRO_0000419711"
FT   MOD_RES         8
FT                   /note="Leucine amide"
FT                   /evidence="ECO:0000269|PubMed:20869420,
FT                   ECO:0000269|PubMed:22848525"
FT   UNSURE          8
FT                   /note="L or I"
FT                   /evidence="ECO:0000269|PubMed:22848525"
SQ   SEQUENCE   8 AA;  910 MW;  922879D5AB47740D CRC64;
     ARPYSFGL