ID   GBG14_HUMAN             Reviewed;          69 AA.
AC   A0A1W2PPG7;
DT   27-SEP-2017, integrated into UniProtKB/Swiss-Prot.
DT   07-JUN-2017, sequence version 1.
DT   03-AUG-2022, entry version 26.
DE   RecName: Full=Putative guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-14 {ECO:0000305};
GN   Name=GNG14 {ECO:0000312|HGNC:HGNC:53439};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15057824; DOI=10.1038/nature02399;
RA   Grimwood J., Gordon L.A., Olsen A.S., Terry A., Schmutz J., Lamerdin J.E.,
RA   Hellsten U., Goodstein D., Couronne O., Tran-Gyamfi M., Aerts A.,
RA   Altherr M., Ashworth L., Bajorek E., Black S., Branscomb E., Caenepeel S.,
RA   Carrano A.V., Caoile C., Chan Y.M., Christensen M., Cleland C.A.,
RA   Copeland A., Dalin E., Dehal P., Denys M., Detter J.C., Escobar J.,
RA   Flowers D., Fotopulos D., Garcia C., Georgescu A.M., Glavina T., Gomez M.,
RA   Gonzales E., Groza M., Hammon N., Hawkins T., Haydu L., Ho I., Huang W.,
RA   Israni S., Jett J., Kadner K., Kimball H., Kobayashi A., Larionov V.,
RA   Leem S.-H., Lopez F., Lou Y., Lowry S., Malfatti S., Martinez D.,
RA   McCready P.M., Medina C., Morgan J., Nelson K., Nolan M., Ovcharenko I.,
RA   Pitluck S., Pollard M., Popkie A.P., Predki P., Quan G., Ramirez L.,
RA   Rash S., Retterer J., Rodriguez A., Rogers S., Salamov A., Salazar A.,
RA   She X., Smith D., Slezak T., Solovyev V., Thayer N., Tice H., Tsai M.,
RA   Ustaszewska A., Vo N., Wagner M., Wheeler J., Wu K., Xie G., Yang J.,
RA   Dubchak I., Furey T.S., DeJong P., Dickson M., Gordon D., Eichler E.E.,
RA   Pennacchio L.A., Richardson P., Stubbs L., Rokhsar D.S., Myers R.M.,
RA   Rubin E.M., Lucas S.M.;
RT   "The DNA sequence and biology of human chromosome 19.";
RL   Nature 428:529-535(2004).
CC   -!- FUNCTION: Guanine nucleotide-binding proteins (G proteins) are involved
CC       as a modulator or transducer in various transmembrane signaling
CC       systems. The beta and gamma chains are required for the GTPase
CC       activity, for replacement of GDP by GTP, and for G protein-effector
CC       interaction. {ECO:0000305}.
CC   -!- SUBUNIT: G proteins are composed of 3 units; alpha, beta and gamma.
CC       {ECO:0000305}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the G protein gamma family. {ECO:0000305}.
CC   -!- CAUTION: Product of a dubious gene prediction. {ECO:0000305}.
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DR   EMBL; AC018761; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; CH471106; EAW84298.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1W2PPG7; -.
DR   SMR; A0A1W2PPG7; -.
DR   BioMuta; GNG14; -.
DR   Antibodypedia; 81930; 1 antibodies from 1 providers.
DR   Ensembl; ENST00000640117.1; ENSP00000491535.1; ENSG00000283980.1.
DR   GeneCards; GNG14; -.
DR   HGNC; HGNC:53439; GNG14.
DR   HPA; ENSG00000283980; Tissue enhanced (brain, pancreas, skin).
DR   neXtProt; NX_A0A1W2PPG7; -.
DR   VEuPathDB; HostDB:ENSG00000283980; -.
DR   GeneTree; ENSGT00940000167831; -.
DR   ChiTaRS; GNG14; human.
DR   Pharos; A0A1W2PPG7; Tdark.
DR   Proteomes; UP000005640; Chromosome 19.
DR   RNAct; A0A1W2PPG7; protein.
DR   Bgee; ENSG00000283980; Expressed in right uterine tube and 82 other tissues.
DR   ExpressionAtlas; A0A1W2PPG7; baseline and differential.
DR   GO; GO:0005834; C:heterotrimeric G-protein complex; IBA:GO_Central.
DR   GO; GO:0031681; F:G-protein beta-subunit binding; IBA:GO_Central.
DR   GO; GO:0007186; P:G protein-coupled receptor signaling pathway; IBA:GO_Central.
DR   CDD; cd00068; GGL; 1.
DR   Gene3D; 4.10.260.10; -; 1.
DR   InterPro; IPR015898; G-protein_gamma-like_dom.
DR   InterPro; IPR036284; GGL_sf.
DR   InterPro; IPR001770; Gprotein-gamma.
DR   PANTHER; PTHR13809; PTHR13809; 1.
DR   PRINTS; PR00321; GPROTEING.
DR   SMART; SM00224; GGL; 1.
DR   SUPFAM; SSF48670; SSF48670; 1.
DR   PROSITE; PS50058; G_PROTEIN_GAMMA; 1.
PE   5: Uncertain;
KW   Cell membrane; Membrane; Reference proteome; Transducer.
FT   CHAIN           1..69
FT                   /note="Putative guanine nucleotide-binding protein
FT                   G(I)/G(S)/G(O) subunit gamma-14"
FT                   /id="PRO_0000441417"
SQ   SEQUENCE   69 AA;  7528 MW;  180E2C0437E87B55 CRC64;
     MSSKVAINSD IGQALWAVEQ LQMEAGIDQV KMAADLLKFC TEQAKNDPFL VGIPAATNSF
     KEKKPYAIL