ID   GBG_LOLFO               Reviewed;          87 AA.
AC   Q01821;
DT   01-APR-1993, integrated into UniProtKB/Swiss-Prot.
DT   01-APR-1993, sequence version 1.
DT   25-MAY-2022, entry version 83.
DE   RecName: Full=Guanine nucleotide-binding protein subunit gamma;
DE   Flags: Precursor;
OS   Loligo forbesii (Veined squid).
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Cephalopoda;
OC   Coleoidea; Decapodiformes; Teuthida; Myopsina; Loliginidae; Loligo.
OX   NCBI_TaxID=6618;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA], AND PARTIAL PROTEIN SEQUENCE.
RC   TISSUE=Retina;
RX   PubMed=1426257; DOI=10.1016/0014-5793(92)80943-b;
RA   Lott J.S., Ryba N.J.P., Pottinger J.D.D., Keen J.N., Carne A.,
RA   Findlay J.B.C.;
RT   "The gamma-subunit of the principal G-protein from squid (Loligo forbesi)
RT   photoreceptors contains a novel N-terminal sequence.";
RL   FEBS Lett. 312:241-244(1992).
RN   [2]
RP   PRELIMINARY PROTEIN SEQUENCE OF 28-72.
RX   PubMed=1930153; DOI=10.1042/bj2790323;
RA   Pottinger J.D.D., Ryba N.J.P., Keen J.N., Findlay J.B.C.;
RT   "The identification and purification of the heterotrimeric GTP-binding
RT   protein from squid (Loligo forbesi) photoreceptors.";
RL   Biochem. J. 279:323-326(1991).
CC   -!- FUNCTION: Guanine nucleotide-binding proteins (G proteins) are involved
CC       as a modulator or transducer in various transmembrane signaling
CC       systems. This major G-protein of the squid photoreceptor is involved in
CC       visual transduction. The beta and gamma chains are required for the
CC       GTPase activity, for replacement of GDP by GTP, and for G protein-
CC       effector interaction.
CC   -!- SUBUNIT: G proteins are composed of 3 units, alpha, beta and gamma.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Lipid-anchor
CC       {ECO:0000305}; Cytoplasmic side {ECO:0000305}.
CC   -!- PTM: The N-terminus is blocked.
CC   -!- SIMILARITY: Belongs to the G protein gamma family. {ECO:0000305}.
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DR   EMBL; Z15112; CAA78816.1; -; mRNA.
DR   PIR; S27275; S27275.
DR   AlphaFoldDB; Q01821; -.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0007165; P:signal transduction; IEA:UniProtKB-KW.
DR   GO; GO:0007601; P:visual perception; IEA:UniProtKB-KW.
PE   1: Evidence at protein level;
KW   Cell membrane; Direct protein sequencing; Lipoprotein; Membrane;
KW   Methylation; Prenylation; Sensory transduction; Transducer; Vision.
FT   CHAIN           1..84
FT                   /note="Guanine nucleotide-binding protein subunit gamma"
FT                   /id="PRO_0000012683"
FT   PROPEP          85..87
FT                   /note="Removed in mature form"
FT                   /evidence="ECO:0000250"
FT                   /id="PRO_0000012684"
FT   MOD_RES         84
FT                   /note="Cysteine methyl ester"
FT                   /evidence="ECO:0000250"
FT   LIPID           84
FT                   /note="S-geranylgeranyl cysteine"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   87 AA;  10278 MW;  BF9E07DEB780B104 CRC64;
     MNKMQGKKKK KEEEEEEERI IPPELWKLII EQYKRQLAKT DVMKVSETVK LHEEKIKEKV
     PTDHIIHAQK PNAWVEETKK SGGCLLV