ID   GBG_NEUCR               Reviewed;          93 AA.
AC   Q7RWT0; Q5PXG1;
DT   27-SEP-2004, integrated into UniProtKB/Swiss-Prot.
DT   04-DEC-2007, sequence version 2.
DT   03-AUG-2022, entry version 101.
DE   RecName: Full=Guanine nucleotide-binding protein subunit gamma;
DE   Flags: Precursor;
GN   Name=gng-1; ORFNames=NCU00041;
OS   Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 /
OS   FGSC 987).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Sordariomycetidae; Sordariales; Sordariaceae; Neurospora.
OX   NCBI_TaxID=367110;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=15701799; DOI=10.1128/ec.4.2.365-378.2005;
RA   Krystofova S., Borkovich K.A.;
RT   "The heterotrimeric G-protein subunits GNG-1 and GNB-1 form a Gbetagamma
RT   dimer required for normal female fertility, asexual development, and galpha
RT   protein levels in Neurospora crassa.";
RL   Eukaryot. Cell 4:365-378(2005).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987;
RX   PubMed=12712197; DOI=10.1038/nature01554;
RA   Galagan J.E., Calvo S.E., Borkovich K.A., Selker E.U., Read N.D.,
RA   Jaffe D.B., FitzHugh W., Ma L.-J., Smirnov S., Purcell S., Rehman B.,
RA   Elkins T., Engels R., Wang S., Nielsen C.B., Butler J., Endrizzi M.,
RA   Qui D., Ianakiev P., Bell-Pedersen D., Nelson M.A., Werner-Washburne M.,
RA   Selitrennikoff C.P., Kinsey J.A., Braun E.L., Zelter A., Schulte U.,
RA   Kothe G.O., Jedd G., Mewes H.-W., Staben C., Marcotte E., Greenberg D.,
RA   Roy A., Foley K., Naylor J., Stange-Thomann N., Barrett R., Gnerre S.,
RA   Kamal M., Kamvysselis M., Mauceli E.W., Bielke C., Rudd S., Frishman D.,
RA   Krystofova S., Rasmussen C., Metzenberg R.L., Perkins D.D., Kroken S.,
RA   Cogoni C., Macino G., Catcheside D.E.A., Li W., Pratt R.J., Osmani S.A.,
RA   DeSouza C.P.C., Glass N.L., Orbach M.J., Berglund J.A., Voelker R.,
RA   Yarden O., Plamann M., Seiler S., Dunlap J.C., Radford A., Aramayo R.,
RA   Natvig D.O., Alex L.A., Mannhaupt G., Ebbole D.J., Freitag M., Paulsen I.,
RA   Sachs M.S., Lander E.S., Nusbaum C., Birren B.W.;
RT   "The genome sequence of the filamentous fungus Neurospora crassa.";
RL   Nature 422:859-868(2003).
CC   -!- SUBUNIT: G proteins are composed of 3 units, alpha, beta and gamma.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000250}; Peripheral membrane
CC       protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the G protein gamma family. {ECO:0000305}.
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DR   EMBL; AY823297; AAV83542.1; -; mRNA.
DR   EMBL; CM002238; EAA26916.2; -; Genomic_DNA.
DR   RefSeq; XP_956152.2; XM_951059.3.
DR   AlphaFoldDB; Q7RWT0; -.
DR   SMR; Q7RWT0; -.
DR   STRING; 5141.EFNCRP00000000474; -.
DR   PRIDE; Q7RWT0; -.
DR   EnsemblFungi; EAA26916; EAA26916; NCU00041.
DR   GeneID; 3872304; -.
DR   KEGG; ncr:NCU00041; -.
DR   VEuPathDB; FungiDB:NCU00041; -.
DR   HOGENOM; CLU_163540_1_1_1; -.
DR   InParanoid; Q7RWT0; -.
DR   Proteomes; UP000001805; Chromosome 3, Linkage Group III.
DR   GO; GO:0005834; C:heterotrimeric G-protein complex; IBA:GO_Central.
DR   GO; GO:0031681; F:G-protein beta-subunit binding; IEA:InterPro.
DR   GO; GO:0007186; P:G protein-coupled receptor signaling pathway; IBA:GO_Central.
DR   GO; GO:0000750; P:pheromone-dependent signal transduction involved in conjugation with cellular fusion; IEA:InterPro.
DR   Gene3D; 4.10.260.10; -; 1.
DR   InterPro; IPR015898; G-protein_gamma-like_dom.
DR   InterPro; IPR036284; GGL_sf.
DR   InterPro; IPR041848; Ste18_fungal.
DR   PANTHER; PTHR28189; PTHR28189; 1.
DR   Pfam; PF00631; G-gamma; 1.
DR   SMART; SM00224; GGL; 1.
DR   SUPFAM; SSF48670; SSF48670; 1.
DR   PROSITE; PS50058; G_PROTEIN_GAMMA; 1.
PE   3: Inferred from homology;
KW   Lipoprotein; Membrane; Methylation; Palmitate; Prenylation;
KW   Reference proteome; Transducer.
FT   CHAIN           1..90
FT                   /note="Guanine nucleotide-binding protein subunit gamma"
FT                   /id="PRO_0000194809"
FT   PROPEP          91..93
FT                   /note="Removed in mature form"
FT                   /evidence="ECO:0000250"
FT                   /id="PRO_0000396772"
FT   REGION          1..22
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         90
FT                   /note="Cysteine methyl ester"
FT                   /evidence="ECO:0000250"
FT   LIPID           89
FT                   /note="S-palmitoyl cysteine"
FT                   /evidence="ECO:0000250"
FT   LIPID           90
FT                   /note="S-farnesyl cysteine"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   93 AA;  10616 MW;  0CD5C350E3098A87 CRC64;
     MPQYASRDVG DPSQIKKNKQ SMADLKLRRL TELNNRLRED LERERIPVSQ AAKSIITYCN
     STRDYMVPSV WGPVPKSEDP YLPQQSSGCC VVM