GBG_SCHPO
ID GBG_SCHPO Reviewed; 72 AA.
AC O94309;
DT 01-FEB-2003, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-1999, sequence version 1.
DT 25-MAY-2022, entry version 103.
DE RecName: Full=Guanine nucleotide-binding protein subunit gamma;
DE Flags: Precursor;
GN Name=git11; ORFNames=SPBC215.04;
OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=284812;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=972 / ATCC 24843;
RX PubMed=11859360; DOI=10.1038/nature724;
RA Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA Nurse P.;
RT "The genome sequence of Schizosaccharomyces pombe.";
RL Nature 415:871-880(2002).
CC -!- SUBUNIT: G proteins are composed of 3 units, alpha, beta and gamma.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000250}; Peripheral membrane
CC protein {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the G protein gamma family. {ECO:0000305}.
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DR EMBL; CU329671; CAA22118.1; -; Genomic_DNA.
DR PIR; T39894; T39894.
DR RefSeq; NP_596681.1; NM_001022604.2.
DR AlphaFoldDB; O94309; -.
DR BioGRID; 277191; 8.
DR STRING; 4896.SPBC215.04.1; -.
DR iPTMnet; O94309; -.
DR PaxDb; O94309; -.
DR EnsemblFungi; SPBC215.04.1; SPBC215.04.1:pep; SPBC215.04.
DR GeneID; 2540666; -.
DR KEGG; spo:SPBC215.04; -.
DR PomBase; SPBC215.04; git11.
DR VEuPathDB; FungiDB:SPBC215.04; -.
DR HOGENOM; CLU_2723639_0_0_1; -.
DR PRO; PR:O94309; -.
DR Proteomes; UP000002485; Chromosome II.
DR GO; GO:0005834; C:heterotrimeric G-protein complex; IDA:PomBase.
DR GO; GO:0010619; P:adenylate cyclase-activating glucose-activated G protein-coupled receptor signaling pathway; IMP:PomBase.
DR GO; GO:0007186; P:G protein-coupled receptor signaling pathway; IBA:GO_Central.
DR GO; GO:0010515; P:negative regulation of induction of conjugation with cellular fusion; IMP:PomBase.
DR GO; GO:0061987; P:negative regulation of transcription from RNA polymerase II promoter by glucose; IMP:PomBase.
PE 3: Inferred from homology;
KW Lipoprotein; Membrane; Methylation; Palmitate; Prenylation;
KW Reference proteome; Transducer.
FT CHAIN 1..69
FT /note="Guanine nucleotide-binding protein subunit gamma"
FT /id="PRO_0000194810"
FT PROPEP 70..72
FT /note="Removed in mature form"
FT /evidence="ECO:0000250"
FT /id="PRO_0000396773"
FT REGION 32..72
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 39..53
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 69
FT /note="Cysteine methyl ester"
FT /evidence="ECO:0000250"
FT LIPID 68
FT /note="S-palmitoyl cysteine"
FT /evidence="ECO:0000250"
FT LIPID 69
FT /note="S-farnesyl cysteine"
FT /evidence="ECO:0000250"
SQ SEQUENCE 72 AA; 7922 MW; 95E1F7A910FD7DC6 CRC64;
METEALLNEK ISVQQARQEF ANYANNIPEP MMVSVAPPKA NPSVSSKTKQ QQHFKPGKAT
KDKATTKCCT IS
