GBLPA_ORYSJ
ID GBLPA_ORYSJ Reviewed; 334 AA.
AC P49027; A0A0P0V6R3; Q0JKA4;
DT 01-FEB-1996, integrated into UniProtKB/Swiss-Prot.
DT 01-FEB-1996, sequence version 1.
DT 25-MAY-2022, entry version 129.
DE RecName: Full=Guanine nucleotide-binding protein subunit beta-like protein A;
DE Short=GPB-LR;
DE AltName: Full=RWD;
DE AltName: Full=Receptor for activated C kinase 1A;
GN Name=RACK1A; OrderedLocusNames=Os01g0686800, LOC_Os01g49290;
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC STRAIN=cv. Nipponbare; TISSUE=Leaf;
RX PubMed=7757340; DOI=10.1093/oxfordjournals.pcp.a078786;
RA Iwasaki Y., Komano M., Ishikawa A., Sasaki T., Asahi T.;
RT "Molecular cloning and characterization of cDNA for a rice protein that
RT contains seven repetitive segments of the Trp-Asp forty-amino-acid repeat
RT (WD-40 repeat).";
RL Plant Cell Physiol. 36:505-510(1995).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=12447438; DOI=10.1038/nature01184;
RA Sasaki T., Matsumoto T., Yamamoto K., Sakata K., Baba T., Katayose Y.,
RA Wu J., Niimura Y., Cheng Z., Nagamura Y., Antonio B.A., Kanamori H.,
RA Hosokawa S., Masukawa M., Arikawa K., Chiden Y., Hayashi M., Okamoto M.,
RA Ando T., Aoki H., Arita K., Hamada M., Harada C., Hijishita S., Honda M.,
RA Ichikawa Y., Idonuma A., Iijima M., Ikeda M., Ikeno M., Ito S., Ito T.,
RA Ito Y., Ito Y., Iwabuchi A., Kamiya K., Karasawa W., Katagiri S.,
RA Kikuta A., Kobayashi N., Kono I., Machita K., Maehara T., Mizuno H.,
RA Mizubayashi T., Mukai Y., Nagasaki H., Nakashima M., Nakama Y.,
RA Nakamichi Y., Nakamura M., Namiki N., Negishi M., Ohta I., Ono N., Saji S.,
RA Sakai K., Shibata M., Shimokawa T., Shomura A., Song J., Takazaki Y.,
RA Terasawa K., Tsuji K., Waki K., Yamagata H., Yamane H., Yoshiki S.,
RA Yoshihara R., Yukawa K., Zhong H., Iwama H., Endo T., Ito H., Hahn J.H.,
RA Kim H.-I., Eun M.-Y., Yano M., Jiang J., Gojobori T.;
RT "The genome sequence and structure of rice chromosome 1.";
RL Nature 420:312-316(2002).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [5]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [6]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT "The genomes of Oryza sativa: a history of duplications.";
RL PLoS Biol. 3:266-281(2005).
RN [7]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=12869764; DOI=10.1126/science.1081288;
RG The rice full-length cDNA consortium;
RT "Collection, mapping, and annotation of over 28,000 cDNA clones from
RT japonica rice.";
RL Science 301:376-379(2003).
RN [8]
RP PROTEIN SEQUENCE OF 7-16.
RC STRAIN=cv. Nipponbare; TISSUE=Embryo;
RX PubMed=14681440; DOI=10.1093/nar/gkh020;
RA Komatsu S., Kojima K., Suzuki K., Ozaki K., Higo K.;
RT "Rice proteome database based on two-dimensional polyacrylamide gel
RT electrophoresis: its status in 2003.";
RL Nucleic Acids Res. 32:D388-D392(2004).
RN [9]
RP FUNCTION, SUBUNIT, INTERACTION WITH RAC1; RAC3; RAC6; RAR1; SGT1 AND RBOHB,
RP SUBCELLULAR LOCATION, INDUCTION, AND IDENTIFICATION BY MASS SPECTROMETRY.
RX PubMed=18723578; DOI=10.1105/tpc.107.054395;
RA Nakashima A., Chen L., Thao N.P., Fujiwara M., Wong H.L., Kuwano M.,
RA Umemura K., Shirasu K., Kawasaki T., Shimamoto K.;
RT "RACK1 functions in rice innate immunity by interacting with the Rac1
RT immune complex.";
RL Plant Cell 20:2265-2279(2008).
CC -!- FUNCTION: Component of the RACK1 regulatory proteins that functions in
CC innate immunity by interacting with multiple proteins in the RAC1
CC immune complex. Acts as positive regulator of reactive oxygen species
CC (ROS) production and is required for resistance against rice blast
CC (M.grisea) infection. {ECO:0000269|PubMed:18723578}.
CC -!- SUBUNIT: Interacts with RAC1, RAC3, RAC6, RAR1, SGT1 and RBOHB.
CC Homodimer and heterodimer with RACK1B (Probable).
CC {ECO:0000305|PubMed:18723578}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:18723578}. Cell
CC membrane {ECO:0000269|PubMed:18723578}. Note=Predominantly found in the
CC cytoplasm.
CC -!- TISSUE SPECIFICITY: Widely expressed.
CC -!- INDUCTION: By auxin, abscisic acid (ABA) and jasmonic acid (JA).
CC {ECO:0000269|PubMed:18723578}.
CC -!- SIMILARITY: Belongs to the WD repeat G protein beta family. Ribosomal
CC protein RACK1 subfamily. {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; D38231; BAA07404.1; -; mRNA.
DR EMBL; AP003452; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AP008207; BAF05824.1; -; Genomic_DNA.
DR EMBL; AP014957; BAS73760.1; -; Genomic_DNA.
DR EMBL; CM000138; EAZ13132.1; -; Genomic_DNA.
DR EMBL; AK060428; BAG87442.1; -; mRNA.
DR EMBL; AK098893; BAG93799.1; -; mRNA.
DR EMBL; AK121587; BAH00562.1; -; mRNA.
DR PIR; T03764; T03764.
DR RefSeq; XP_015620921.1; XM_015765435.1.
DR AlphaFoldDB; P49027; -.
DR SMR; P49027; -.
DR STRING; 4530.OS01T0686800-02; -.
DR PaxDb; P49027; -.
DR PRIDE; P49027; -.
DR EnsemblPlants; Os01t0686800-01; Os01t0686800-01; Os01g0686800.
DR EnsemblPlants; Os01t0686800-02; Os01t0686800-02; Os01g0686800.
DR GeneID; 4324115; -.
DR Gramene; Os01t0686800-01; Os01t0686800-01; Os01g0686800.
DR Gramene; Os01t0686800-02; Os01t0686800-02; Os01g0686800.
DR KEGG; osa:4324115; -.
DR eggNOG; KOG0279; Eukaryota.
DR HOGENOM; CLU_000288_57_7_1; -.
DR InParanoid; P49027; -.
DR OMA; TNCKIRS; -.
DR OrthoDB; 805365at2759; -.
DR Proteomes; UP000000763; Chromosome 1.
DR Proteomes; UP000007752; Chromosome 1.
DR Proteomes; UP000059680; Chromosome 1.
DR Genevisible; P49027; OS.
DR GO; GO:0005737; C:cytoplasm; IDA:UniProtKB.
DR GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0005886; C:plasma membrane; IDA:UniProtKB.
DR GO; GO:0015935; C:small ribosomal subunit; IEA:InterPro.
DR GO; GO:0005080; F:protein kinase C binding; IBA:GO_Central.
DR GO; GO:0043022; F:ribosome binding; IBA:GO_Central.
DR GO; GO:0050832; P:defense response to fungus; IMP:UniProtKB.
DR GO; GO:0001934; P:positive regulation of protein phosphorylation; IBA:GO_Central.
DR GO; GO:0060267; P:positive regulation of respiratory burst; IMP:UniProtKB.
DR GO; GO:0072344; P:rescue of stalled ribosome; IBA:GO_Central.
DR GO; GO:0007165; P:signal transduction; IEA:UniProtKB-KW.
DR Gene3D; 2.130.10.10; -; 1.
DR InterPro; IPR045223; Asc1/RACK1.
DR InterPro; IPR020472; G-protein_beta_WD-40_rep.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR001680; WD40_repeat.
DR InterPro; IPR019775; WD40_repeat_CS.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR PANTHER; PTHR19868; PTHR19868; 1.
DR Pfam; PF00400; WD40; 7.
DR PRINTS; PR00320; GPROTEINBRPT.
DR SMART; SM00320; WD40; 7.
DR SUPFAM; SSF50978; SSF50978; 1.
DR PROSITE; PS00678; WD_REPEATS_1; 5.
DR PROSITE; PS50082; WD_REPEATS_2; 5.
DR PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE 1: Evidence at protein level;
KW Cell membrane; Cytoplasm; Direct protein sequencing; Membrane;
KW Plant defense; Reference proteome; Repeat; Ribonucleoprotein;
KW Ribosomal protein; Transducer; WD repeat.
FT CHAIN 1..334
FT /note="Guanine nucleotide-binding protein subunit beta-like
FT protein A"
FT /id="PRO_0000127753"
FT REPEAT 16..47
FT /note="WD 1"
FT REPEAT 73..103
FT /note="WD 2"
FT REPEAT 115..145
FT /note="WD 3"
FT REPEAT 163..195
FT /note="WD 4"
FT REPEAT 207..237
FT /note="WD 5"
FT REPEAT 248..277
FT /note="WD 6"
FT REPEAT 296..326
FT /note="WD 7"
SQ SEQUENCE 334 AA; 36232 MW; F0B356A4CE9364D0 CRC64;
MAGAQESLVL AGVMHGHNDV VTAIATPIDN SPFIVSSSRD KSLLVWDLTN PVQNVGEGAG
ASEYGVPFRR LTGHSHFVQD VVLSSDGQFA LSGSWDGELR LWDLSTGVTT RRFVGHDKDV
LSVAFSVDNR QIVSASRDRT IKLWNTLGEC KYTIGGDLGG GEGHNGWVSC VRFSPNTFQP
TIVSGSWDRT VKVWNLTNCK LRCNLEGHGG YVNAVAVSPD GSLCASGGKD GVTLLWDLAE
GKRLYSLDAG SIIHSLCFSP NRYWLCAATQ DSIKIWDLES KHIVQDLKPE IPVSKNQMLY
CTSLNWSADG STLYAGYTDG TIRIYKISGF SYAG
