ID   GBLP_ENCCU              Reviewed;         334 AA.
AC   Q8SRB0;
DT   01-SEP-2009, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2002, sequence version 1.
DT   25-MAY-2022, entry version 95.
DE   RecName: Full=Guanine nucleotide-binding protein subunit beta-like protein;
GN   OrderedLocusNames=ECU08_1110;
OS   Encephalitozoon cuniculi (strain GB-M1) (Microsporidian parasite).
OC   Eukaryota; Fungi; Fungi incertae sedis; Microsporidia; Unikaryonidae;
OC   Encephalitozoon.
OX   NCBI_TaxID=284813;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=GB-M1;
RX   PubMed=11719806; DOI=10.1038/35106579;
RA   Katinka M.D., Duprat S., Cornillot E., Metenier G., Thomarat F.,
RA   Prensier G., Barbe V., Peyretaillade E., Brottier P., Wincker P.,
RA   Delbac F., El Alaoui H., Peyret P., Saurin W., Gouy M., Weissenbach J.,
RA   Vivares C.P.;
RT   "Genome sequence and gene compaction of the eukaryote parasite
RT   Encephalitozoon cuniculi.";
RL   Nature 414:450-453(2001).
RN   [2]
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS], DEVELOPMENTAL
RP   STAGE, AND SUBCELLULAR LOCATION.
RX   PubMed=16691553; DOI=10.1002/pmic.200500796;
RA   Brosson D., Kuhn L., Delbac F., Garin J., Vivares C.P., Texier C.;
RT   "Proteomic analysis of the eukaryotic parasite Encephalitozoon cuniculi
RT   (microsporidia): a reference map for proteins expressed in late sporogonial
RT   stages.";
RL   Proteomics 6:3625-3635(2006).
CC   -!- DEVELOPMENTAL STAGE: Expressed in late sporogonial stages.
CC       {ECO:0000269|PubMed:16691553}.
CC   -!- SIMILARITY: Belongs to the WD repeat G protein beta family.
CC       {ECO:0000305}.
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DR   EMBL; AL590448; CAD26417.1; -; Genomic_DNA.
DR   RefSeq; NP_597241.1; NM_001041850.1.
DR   AlphaFoldDB; Q8SRB0; -.
DR   SMR; Q8SRB0; -.
DR   STRING; 284813.Q8SRB0; -.
DR   GeneID; 859663; -.
DR   KEGG; ecu:ECU08_1110; -.
DR   VEuPathDB; MicrosporidiaDB:ECU08_1110; -.
DR   HOGENOM; CLU_831632_0_0_1; -.
DR   InParanoid; Q8SRB0; -.
DR   OMA; HRFEGHA; -.
DR   OrthoDB; 805365at2759; -.
DR   Proteomes; UP000000819; Chromosome VIII.
DR   Gene3D; 2.130.10.10; -; 2.
DR   InterPro; IPR020472; G-protein_beta_WD-40_rep.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR001680; WD40_repeat.
DR   InterPro; IPR019775; WD40_repeat_CS.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   Pfam; PF00400; WD40; 3.
DR   PRINTS; PR00320; GPROTEINBRPT.
DR   SMART; SM00320; WD40; 6.
DR   SUPFAM; SSF50978; SSF50978; 1.
DR   PROSITE; PS00678; WD_REPEATS_1; 3.
DR   PROSITE; PS50082; WD_REPEATS_2; 3.
DR   PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE   1: Evidence at protein level;
KW   Reference proteome; Repeat; WD repeat.
FT   CHAIN           1..334
FT                   /note="Guanine nucleotide-binding protein subunit beta-like
FT                   protein"
FT                   /id="PRO_0000383332"
FT   REPEAT          14..55
FT                   /note="WD 1"
FT   REPEAT          65..104
FT                   /note="WD 2"
FT   REPEAT          106..145
FT                   /note="WD 3"
FT   REPEAT          152..192
FT                   /note="WD 4"
FT   REPEAT          215..256
FT                   /note="WD 5"
FT   REPEAT          257..294
FT                   /note="WD 6"
SQ   SEQUENCE   334 AA;  36751 MW;  9576925DCE2DB303 CRC64;
     MSSAELEVLE YLNGHKDEVK GLKIVRVSGR EILYSSSRDK KVFSWDLHSK IDSEFGKILK
     LYDGGHSKRI NGLDVSKDGN MMVTVGSDGI GRIWDTESKK SILLEGHGRD VLCVSINSND
     TKIVTGSVDR TMNLYNTKGD LVLKMGRDME MMHRGWINCV TFHPTEESIL ASGSADGTVK
     IWDLDTQEHL QTYLGGAYVD YEKAKEKKTS PVDYDESKSV TAMAFSKDGS ILTYGEKSGK
     MYLVKVDSKE CIQSFDAIVP VRSIAVGETE PVIALGTDES VIIWETISSR VIASYNLKEI
     GNGVRCLSLA FSGSTLYCGL STGAIVPLEL RKSD