ID   GBLP_TOBAC              Reviewed;         326 AA.
AC   P49026;
DT   01-FEB-1996, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1996, sequence version 1.
DT   25-MAY-2022, entry version 77.
DE   RecName: Full=Guanine nucleotide-binding protein subunit beta-like protein;
GN   Name=ARCA;
OS   Nicotiana tabacum (Common tobacco).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae;
OC   Nicotiana.
OX   NCBI_TaxID=4097;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=cv. Bright Yellow 2;
RX   PubMed=8248221; DOI=10.1073/pnas.90.23.11152;
RA   Ishida S., Takahashi Y., Nagata T.;
RT   "Isolation of cDNA of an auxin-regulated gene encoding a G protein beta
RT   subunit-like protein from tobacco BY-2 cells.";
RL   Proc. Natl. Acad. Sci. U.S.A. 90:11152-11156(1993).
CC   -!- FUNCTION: May have a role in cell division.
CC   -!- TISSUE SPECIFICITY: Predominantly expressed in roots. Also found in
CC       leaves, flower buds, shoot tips, stems and young seedlings.
CC   -!- SIMILARITY: Belongs to the WD repeat G protein beta family. Ribosomal
CC       protein RACK1 subfamily. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; U03559; BAA04478.1; -; Genomic_DNA.
DR   PIR; T02340; T02340.
DR   RefSeq; NP_001311744.1; NM_001324815.1.
DR   AlphaFoldDB; P49026; -.
DR   SMR; P49026; -.
DR   STRING; 4097.P49026; -.
DR   GeneID; 107763849; -.
DR   KEGG; nta:107763849; -.
DR   Proteomes; UP000084051; Unplaced.
DR   GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0015935; C:small ribosomal subunit; IEA:InterPro.
DR   GO; GO:0005080; F:protein kinase C binding; IBA:GO_Central.
DR   GO; GO:0043022; F:ribosome binding; IBA:GO_Central.
DR   GO; GO:0001934; P:positive regulation of protein phosphorylation; IBA:GO_Central.
DR   GO; GO:0072344; P:rescue of stalled ribosome; IBA:GO_Central.
DR   Gene3D; 2.130.10.10; -; 1.
DR   InterPro; IPR045223; Asc1/RACK1.
DR   InterPro; IPR020472; G-protein_beta_WD-40_rep.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR001680; WD40_repeat.
DR   InterPro; IPR019775; WD40_repeat_CS.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   PANTHER; PTHR19868; PTHR19868; 1.
DR   Pfam; PF00400; WD40; 7.
DR   PRINTS; PR00320; GPROTEINBRPT.
DR   SMART; SM00320; WD40; 7.
DR   SUPFAM; SSF50978; SSF50978; 1.
DR   PROSITE; PS00678; WD_REPEATS_1; 4.
DR   PROSITE; PS50082; WD_REPEATS_2; 6.
DR   PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE   2: Evidence at transcript level;
KW   Reference proteome; Repeat; Ribonucleoprotein; Ribosomal protein;
KW   WD repeat.
FT   CHAIN           1..326
FT                   /note="Guanine nucleotide-binding protein subunit beta-like
FT                   protein"
FT                   /id="PRO_0000127755"
FT   REPEAT          14..45
FT                   /note="WD 1"
FT   REPEAT          62..92
FT                   /note="WD 2"
FT   REPEAT          104..134
FT                   /note="WD 3"
FT   REPEAT          148..180
FT                   /note="WD 4"
FT   REPEAT          192..222
FT                   /note="WD 5"
FT   REPEAT          233..262
FT                   /note="WD 6"
FT   REPEAT          292..322
FT                   /note="WD 7"
FT   VARIANT         25
FT                   /note="A -> P"
FT   VARIANT         46
FT                   /note="I -> L"
FT   VARIANT         116
FT                   /note="V -> A"
FT   VARIANT         142
FT                   /note="T -> I"
FT   VARIANT         188
FT                   /note="L -> A"
FT   VARIANT         200
FT                   /note="P -> T"
FT   VARIANT         267
FT                   /note="S -> T"
FT   VARIANT         284
FT                   /note="S -> A"
FT   VARIANT         301
FT                   /note="S -> G"
FT   VARIANT         324
FT                   /note="D -> G"
SQ   SEQUENCE   326 AA;  35946 MW;  680DEDA14AB6488D CRC64;
     MSQESLVLRG TMRAHTDWVT AIATAVDNSD MIVTSSRDKS IIVWSITKDG PQYGVPRRRL
     TGHGHFVQDV VLSSDGMFAL SGSWDGELRL WDLQAGTTAR RFVGHTKDVL SVAFSVDNRQ
     IVSASRDKSI RLWNTLGECK YTIQDGDSHS DWVSCVRFSP NNLQPTIVSG SWDRTVKIWN
     LTNCKLRLTL AGHTGYVNTP AVSPDGSLCA SGGKDGVILL WDLAEGKKLY SLESGSIIHS
     LCFSPNRYWL CAATESSIKI WDLESKSIVD DLKVDLKQES EMSSEGTASG KNKVIYCTSL
     SWSADGSTLF SGYTDGLIRV WGIDRY