GBLP_TRYBR
ID GBLP_TRYBR Reviewed; 318 AA.
AC P69104; O61075; Q94775;
DT 15-FEB-2005, integrated into UniProtKB/Swiss-Prot.
DT 15-FEB-2005, sequence version 1.
DT 25-MAY-2022, entry version 55.
DE RecName: Full=Guanine nucleotide-binding protein subunit beta-like protein;
DE AltName: Full=Activated protein kinase C receptor homolog;
DE AltName: Full=Track;
OS Trypanosoma brucei rhodesiense.
OC Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC Trypanosomatida; Trypanosomatidae; Trypanosoma.
OX NCBI_TaxID=31286;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC STRAIN=ILTat 1.1;
RX PubMed=10200516; DOI=10.1038/sj.cdd.4400393;
RA Welburn S.C., Murphy N.B.;
RT "Prohibitin and RACK homologues are up-regulated in trypanosomes induced to
RT undergo apoptosis and in naturally occurring terminally differentiated
RT forms.";
RL Cell Death Differ. 5:615-622(1998).
CC -!- SIMILARITY: Belongs to the WD repeat G protein beta family. Ribosomal
CC protein RACK1 subfamily. {ECO:0000305}.
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DR EMBL; AF049902; AAC05497.1; -; mRNA.
DR AlphaFoldDB; P69104; -.
DR SMR; P69104; -.
DR GO; GO:0015935; C:small ribosomal subunit; IEA:InterPro.
DR GO; GO:0043022; F:ribosome binding; IEA:InterPro.
DR Gene3D; 2.130.10.10; -; 1.
DR InterPro; IPR045223; Asc1/RACK1.
DR InterPro; IPR020472; G-protein_beta_WD-40_rep.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR001680; WD40_repeat.
DR InterPro; IPR019775; WD40_repeat_CS.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR PANTHER; PTHR19868; PTHR19868; 1.
DR Pfam; PF00400; WD40; 5.
DR PRINTS; PR00320; GPROTEINBRPT.
DR SMART; SM00320; WD40; 7.
DR SUPFAM; SSF50978; SSF50978; 1.
DR PROSITE; PS00678; WD_REPEATS_1; 4.
DR PROSITE; PS50082; WD_REPEATS_2; 5.
DR PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE 2: Evidence at transcript level;
KW Repeat; Ribonucleoprotein; Ribosomal protein; WD repeat.
FT CHAIN 1..318
FT /note="Guanine nucleotide-binding protein subunit beta-like
FT protein"
FT /id="PRO_0000127747"
FT REPEAT 11..44
FT /note="WD 1"
FT REPEAT 65..95
FT /note="WD 2"
FT REPEAT 107..137
FT /note="WD 3"
FT REPEAT 150..182
FT /note="WD 4"
FT REPEAT 194..224
FT /note="WD 5"
FT REPEAT 235..264
FT /note="WD 6"
FT REPEAT 282..315
FT /note="WD 7"
SQ SEQUENCE 318 AA; 34690 MW; A5B54D287A170972 CRC64;
MAVAYEGQLT GHRGWVTSLA CPQTPETATK VVSTSRDKTL LSWGPNPDRH SSECSYGLPD
RRLEGHSAFV SDVALSNNGN FAVSASWDHS LRLWNLQNGQ CQYKFLGHTK DVLSVAFSPD
NRQIVSGGRD NALRVWNVKG ECMHTLSRGA HTDWVSCVRF SPSLDAPVIV SGGWDNLVKV
WDLATGRLVT DLKGHTNYVT SVTVSPDGSL CASSDKDGVA RLWDLTKGEA LSEMAAGAPI
NQICFSPNRY WMCAATEKGI RIFDLENKDI IVELAPEHQG SKKIVPECVS IAWSADGSTL
YSGYTDNVIR VWGVSENA