GBPA_VIBC3
ID GBPA_VIBC3 Reviewed; 485 AA.
AC A5F0H4; C3M6A5;
DT 26-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT 12-JUN-2007, sequence version 1.
DT 25-MAY-2022, entry version 72.
DE RecName: Full=GlcNAc-binding protein A {ECO:0000255|HAMAP-Rule:MF_01905};
DE Flags: Precursor;
GN Name=gbpA {ECO:0000255|HAMAP-Rule:MF_01905};
GN OrderedLocusNames=VC0395_0423, VC395_A0835;
OS Vibrio cholerae serotype O1 (strain ATCC 39541 / Classical Ogawa 395 /
OS O395).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC Vibrio.
OX NCBI_TaxID=345073;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 39541 / Classical Ogawa 395 / O395;
RA Heidelberg J.;
RL Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 39541 / Classical Ogawa 395 / O395;
RX PubMed=19115014; DOI=10.1371/journal.pone.0004053;
RA Feng L., Reeves P.R., Lan R., Ren Y., Gao C., Zhou Z., Ren Y., Cheng J.,
RA Wang W., Wang J., Qian W., Li D., Wang L.;
RT "A recalibrated molecular clock and independent origins for the cholera
RT pandemic clones.";
RL PLoS ONE 3:E4053-E4053(2008).
CC -!- FUNCTION: Probably interacts with GlcNAc residues. May promote
CC attachment to both epithelial cell surfaces and chitin.
CC {ECO:0000255|HAMAP-Rule:MF_01905}.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000255|HAMAP-Rule:MF_01905}.
CC -!- SIMILARITY: Belongs to the GbpA family. {ECO:0000255|HAMAP-
CC Rule:MF_01905}.
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DR EMBL; CP000626; ABQ18997.1; -; Genomic_DNA.
DR EMBL; CP001236; ACP11668.1; -; Genomic_DNA.
DR RefSeq; WP_000744638.1; NZ_JAACZH010000012.1.
DR AlphaFoldDB; A5F0H4; -.
DR SMR; A5F0H4; -.
DR STRING; 345073.VC395_A0835; -.
DR CAZy; AA10; Auxiliary Activities 10.
DR CAZy; CBM73; Carbohydrate-Binding Module Family 73.
DR EnsemblBacteria; ABQ18997; ABQ18997; VC0395_0423.
DR KEGG; vco:VC0395_0423; -.
DR KEGG; vcr:VC395_A0835; -.
DR PATRIC; fig|345073.21.peg.3566; -.
DR eggNOG; COG3397; Bacteria.
DR HOGENOM; CLU_039396_2_0_6; -.
DR OMA; WTFTANH; -.
DR Proteomes; UP000000249; Chromosome 1.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0008061; F:chitin binding; IEA:UniProtKB-UniRule.
DR HAMAP; MF_01905; GbpA; 1.
DR InterPro; IPR004302; Cellulose/chitin-bd_N.
DR InterPro; IPR041029; GbpA_2.
DR InterPro; IPR020879; GlcNAc-bd_A.
DR InterPro; IPR014756; Ig_E-set.
DR Pfam; PF18416; GbpA_2; 1.
DR Pfam; PF03067; LPMO_10; 1.
DR SUPFAM; SSF81296; SSF81296; 1.
PE 3: Inferred from homology;
KW Chitin-binding; Secreted; Signal.
FT SIGNAL 1..23
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01905"
FT CHAIN 24..485
FT /note="GlcNAc-binding protein A"
FT /id="PRO_1000073695"
FT DOMAIN 24..201
FT /note="Chitin-binding type-4"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01905"
FT DOMAIN 437..478
FT /note="Chitin-binding type-3"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01905"
SQ SEQUENCE 485 AA; 53628 MW; 7AAEED41B28336CC CRC64;
MKKQPKMTAI ALILSGISGL AYGHGYVSAV ENGVAEGRVT LCKFAANGTG EKNTHCGAIQ
YEPQSVEGPD GFPVTGPRDG KIASAESALA AALDEQTADR WVKRPIQAGP QTFEWTFTAN
HVTKDWKYYI TKPNWNPNQP LSRDAFDLNP FCVVEGNMVQ PPKRVSHECI VPEREGYQVI
LAVWDVGDTA ASFYNVIDVK FDGNGPVLPD WNPAGQIIPS MDLSIGDTVY TRVFDNEGEN
PAYRTELKID SETLTKANQW SYALATKINQ TQKQQRAGQL NGDQFVPVYG TNPIYLKEGS
GLKSVEIGYQ IEAPQPEYSL TVSGLAKEYE IGEQPIQLDL TLEAQGEMSA ELTVYNHHQK
PLASWSQAMT DGELKSVTLE LSEAKAGHHM LVSRIKDRDG NLQDQQTLDF MLVEPQTPPT
PGDYDFVFPN GLKEYVAGTK VLASDGAIYQ CKPWPYSGYC QQWTSNATQY QPGTGSHWEM
AWDKR
