ID   GBPA_VIBCM              Reviewed;         485 AA.
AC   C3LW75;
DT   28-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT   16-JUN-2009, sequence version 1.
DT   25-MAY-2022, entry version 59.
DE   RecName: Full=GlcNAc-binding protein A {ECO:0000255|HAMAP-Rule:MF_01905};
DE   Flags: Precursor;
GN   Name=gbpA {ECO:0000255|HAMAP-Rule:MF_01905}; OrderedLocusNames=VCM66_A0770;
OS   Vibrio cholerae serotype O1 (strain M66-2).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC   Vibrio.
OX   NCBI_TaxID=579112;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=M66-2;
RX   PubMed=19115014; DOI=10.1371/journal.pone.0004053;
RA   Feng L., Reeves P.R., Lan R., Ren Y., Gao C., Zhou Z., Ren Y., Cheng J.,
RA   Wang W., Wang J., Qian W., Li D., Wang L.;
RT   "A recalibrated molecular clock and independent origins for the cholera
RT   pandemic clones.";
RL   PLoS ONE 3:E4053-E4053(2008).
CC   -!- FUNCTION: Probably interacts with GlcNAc residues. May promote
CC       attachment to both epithelial cell surfaces and chitin.
CC       {ECO:0000255|HAMAP-Rule:MF_01905}.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000255|HAMAP-Rule:MF_01905}.
CC   -!- SIMILARITY: Belongs to the GbpA family. {ECO:0000255|HAMAP-
CC       Rule:MF_01905}.
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DR   EMBL; CP001234; ACP07730.1; -; Genomic_DNA.
DR   RefSeq; WP_000744634.1; NC_012580.1.
DR   AlphaFoldDB; C3LW75; -.
DR   SMR; C3LW75; -.
DR   CAZy; AA10; Auxiliary Activities 10.
DR   CAZy; CBM73; Carbohydrate-Binding Module Family 73.
DR   EnsemblBacteria; ACP07730; ACP07730; VCM66_A0770.
DR   KEGG; vcm:VCM66_A0770; -.
DR   HOGENOM; CLU_039396_2_0_6; -.
DR   OMA; WTFTANH; -.
DR   Proteomes; UP000001217; Chromosome II.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0008061; F:chitin binding; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_01905; GbpA; 1.
DR   InterPro; IPR004302; Cellulose/chitin-bd_N.
DR   InterPro; IPR041029; GbpA_2.
DR   InterPro; IPR020879; GlcNAc-bd_A.
DR   InterPro; IPR014756; Ig_E-set.
DR   Pfam; PF18416; GbpA_2; 1.
DR   Pfam; PF03067; LPMO_10; 1.
DR   SUPFAM; SSF81296; SSF81296; 1.
PE   3: Inferred from homology;
KW   Chitin-binding; Secreted; Signal.
FT   SIGNAL          1..23
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01905"
FT   CHAIN           24..485
FT                   /note="GlcNAc-binding protein A"
FT                   /id="PRO_1000188768"
FT   DOMAIN          24..201
FT                   /note="Chitin-binding type-4"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01905"
FT   DOMAIN          437..478
FT                   /note="Chitin-binding type-3"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01905"
SQ   SEQUENCE   485 AA;  53636 MW;  F264D9647A6A3D19 CRC64;
     MKKQPKMTAI ALILSGISGL AYGHGYVSAV ENGVAEGRVT LCKFAANGTG EKNTHCGAIQ
     YEPQSVEGPD GFPVTGPRDG KIASAESALA AALDEQTADR WVKRPIQAGP QTFEWTFTAN
     HVTKDWKYYI TKPNWNPNQP LSRDAFDLNP FCVVEGNMVQ PPKRVNHECI VPEREGYQVI
     LAVWDVGDTA ASFYNVIDVK FDGNGPVLPD WNPAGQIIPS MDLSIGDTVY TRVFDNEGEN
     PAYRTELKID SETLTKANQW SYALATKINQ TQKQQRAGQL NGDQFVPVYG TNPIYLKEGS
     GLKSVEIGYQ IEAPQPEYSL TVSGLAKEYE IGEQPIQLDL TLEAQGEMSA ELTVYNHHQK
     PLASWSQAMT DGELKSVTLE LSEAKAGHHM LVSRIKDRDG NLQDQQTLDF MLVEPQTPPT
     PGDYDFVFPN GLKEYVAGTK VLASDGAIYQ CKPWPYSGYC QQWTSNATQY QPGTGSHWEM
     AWDKH