ID   GBPH_PLAFB              Reviewed;         427 AA.
AC   P32072;
DT   01-OCT-1993, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1993, sequence version 1.
DT   25-MAY-2022, entry version 50.
DE   RecName: Full=Glycophorin-binding protein-related antigen;
GN   Name=GBPH;
OS   Plasmodium falciparum (isolate FCBR / Columbia).
OC   Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC   Plasmodiidae; Plasmodium; Plasmodium (Laverania).
OX   NCBI_TaxID=33631;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=1775169; DOI=10.1016/0166-6851(91)90069-i;
RA   Nolte D., Hundt E., Langsley G., Knapp B.;
RT   "A Plasmodium falciparum blood stage antigen highly homologous to the
RT   glycophorin binding protein GBP.";
RL   Mol. Biochem. Parasitol. 49:253-264(1991).
CC   -!- DEVELOPMENTAL STAGE: Expressed during the blood stage of the parasite.
CC   -!- MISCELLANEOUS: P.falciparum undergoes three cycles of development in
CC       its vertebrate host: the hepatic cycle; the asexual blood cycle, which
CC       includes the extracellular merozoite and the intraerythrocytic
CC       schizont; and the sexual gametocyte cycle.
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DR   EMBL; M65160; AAA29609.1; -; Genomic_DNA.
DR   PIR; A45636; A45636.
DR   AlphaFoldDB; P32072; -.
DR   InterPro; IPR003681; Glycophorin-bd.
DR   Pfam; PF02526; GBP_repeat; 8.
DR   PROSITE; PS51069; GBP; 8.
PE   2: Evidence at transcript level;
KW   Malaria; Repeat.
FT   CHAIN           1..427
FT                   /note="Glycophorin-binding protein-related antigen"
FT                   /id="PRO_0000217187"
FT   REPEAT          109..149
FT                   /note="GBP 1"
FT   REPEAT          150..189
FT                   /note="GBP 2"
FT   REPEAT          190..229
FT                   /note="GBP 3"
FT   REPEAT          230..269
FT                   /note="GBP 4"
FT   REPEAT          270..307
FT                   /note="GBP 5"
FT   REPEAT          308..347
FT                   /note="GBP 6"
FT   REPEAT          348..387
FT                   /note="GBP 7"
FT   REPEAT          388..427
FT                   /note="GBP 8"
SQ   SEQUENCE   427 AA;  48260 MW;  C313029C06704C44 CRC64;
     MRISKASNIE STGVSNCKNF NSKNCSKYSL MEVQNKNEKK RSLTSFHAKN ITLIFGIIYV
     ALLGVYICAS QYKQAADYSF RESRVLAEGK STSKKNAKTA LRKTKQTTLT SADPEGQIMK
     AWAADPEYRK HLNVLYQILN NTDPNDELET SADPEGQIMK AYAADPEYRK HLNVLYQILN
     NTDPNDEVES SADPEGQIMK AYAADPEYRK HVNVLYQILN NTDPNDELET SADPEGQIMK
     AYAADPEYRK HVNVLYQILN HTDSSEVETS ADPEGQIMKA YAADPEYRKH VNVLYQILNH
     TDSSEVETSA DPEGQIMKAY AADPEYRKHV NVLYQILNNT DPNDELETSA DPEGQIMKAY
     AADPEYRKHV NVLYQILNNT DPNDELETSA DPEGQIMKAY AADPEYRKHV NVLYQILNNT
     DPNDESS