ID   3NOH3_BUNMU             Reviewed;         103 AA.
AC   Q9YGH0;
DT   13-APR-2004, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-1999, sequence version 1.
DT   25-MAY-2022, entry version 65.
DE   RecName: Full=Cytotoxin-like protein TA-BMBGT3;
DE   Flags: Precursor;
OS   Bungarus multicinctus (Many-banded krait).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera;
OC   Serpentes; Colubroidea; Elapidae; Bungarinae; Bungarus.
OX   NCBI_TaxID=8616;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   TISSUE=Venom gland;
RA   Chang L.-S.;
RL   Submitted (APR-1998) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
CC   -!- TISSUE SPECIFICITY: Expressed by the venom gland. {ECO:0000305}.
CC   -!- MISCELLANEOUS: Does not bind to muscarinic acetylcholine receptors M1
CC       and M2 (CHRM1/CHRM2). Is unable to compete with alpha-bungarotoxin for
CC       binding to nAchR at concentrations up to 100 uM. Is not toxic to mice
CC       at doses up to 3 mg/kg. {ECO:0000250|UniProtKB:Q9PW19}.
CC   -!- SIMILARITY: Belongs to the snake three-finger toxin family. Ancestral
CC       subfamily. Orphan group XVII sub-subfamily. {ECO:0000305}.
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DR   EMBL; Y17059; CAA76607.1; -; mRNA.
DR   AlphaFoldDB; Q9YGH0; -.
DR   SMR; Q9YGH0; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0090729; F:toxin activity; IEA:InterPro.
DR   CDD; cd00206; snake_toxin; 1.
DR   Gene3D; 2.10.60.10; -; 1.
DR   InterPro; IPR003571; Snake_3FTx.
DR   InterPro; IPR045860; Snake_toxin-like_sf.
DR   SUPFAM; SSF57302; SSF57302; 1.
PE   3: Inferred from homology;
KW   Disulfide bond; Secreted; Signal.
FT   SIGNAL          1..21
FT                   /evidence="ECO:0000255"
FT   CHAIN           22..103
FT                   /note="Cytotoxin-like protein TA-BMBGT3"
FT                   /id="PRO_0000035485"
FT   DISULFID        24..45
FT                   /evidence="ECO:0000250|UniProtKB:P81782"
FT   DISULFID        27..37
FT                   /evidence="ECO:0000250|UniProtKB:P81782"
FT   DISULFID        38..72
FT                   /evidence="ECO:0000250|UniProtKB:P81782"
FT   DISULFID        76..90
FT                   /evidence="ECO:0000250|UniProtKB:P81782"
FT   DISULFID        91..96
FT                   /evidence="ECO:0000250|UniProtKB:P81782"
SQ   SEQUENCE   103 AA;  11433 MW;  6CE923E3BC63C659 CRC64;
     MKTLLLTLVV VTIICLDLGY TEMCNMCVRP YPFMSSCCPE GQDRCYKSYW VNENRKQEAY
     HGKYPVILER GCVTACTGPG SGSIYNLYTC CPTNRCGSSS TSG