ID   GCDD_ACIFV              Reviewed;         107 AA.
AC   Q9ZAA8; D2RM88;
DT   16-JAN-2004, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-1999, sequence version 1.
DT   03-AUG-2022, entry version 100.
DE   RecName: Full=Glutaconyl-CoA decarboxylase subunit delta;
DE            EC=7.2.4.5;
GN   Name=gcdD; OrderedLocusNames=Acfer_1836;
OS   Acidaminococcus fermentans (strain ATCC 25085 / DSM 20731 / CCUG 9996 / CIP
OS   106432 / VR4).
OC   Bacteria; Firmicutes; Negativicutes; Acidaminococcales; Acidaminococcaceae;
OC   Acidaminococcus.
OX   NCBI_TaxID=591001;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=10027965; DOI=10.1046/j.1365-2958.1999.01189.x;
RA   Braune A., Bendrat K., Rospert S., Buckel W.;
RT   "The sodium ion translocating glutaconyl-CoA decarboxylase from
RT   Acidaminococcus fermentans: cloning and function of the genes forming a
RT   second operon.";
RL   Mol. Microbiol. 31:473-487(1999).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 25085 / DSM 20731 / CCUG 9996 / CIP 106432 / VR4;
RX   PubMed=21304687; DOI=10.4056/sigs.1002553;
RA   Chang Y.J., Pukall R., Saunders E., Lapidus A., Copeland A., Nolan M.,
RA   Glavina Del Rio T., Lucas S., Chen F., Tice H., Cheng J.F., Han C.,
RA   Detter J.C., Bruce D., Goodwin L., Pitluck S., Mikhailova N., Liolios K.,
RA   Pati A., Ivanova N., Mavromatis K., Chen A., Palaniappan K., Land M.,
RA   Hauser L., Jeffries C.D., Brettin T., Rohde M., Goker M., Bristow J.,
RA   Eisen J.A., Markowitz V., Hugenholtz P., Kyrpides N.C., Klenk H.P.;
RT   "Complete genome sequence of Acidaminococcus fermentans type strain
RT   (VR4).";
RL   Stand. Genomic Sci. 3:1-14(2010).
CC   -!- FUNCTION: Part of the primary sodium pump glutaconyl-CoA decarboxylase
CC       (GCD). Possible membrane anchor for the alpha subunit.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=(2E)-glutaconyl-CoA + H(+) + Na(+)(in) = (2E)-butenoyl-CoA +
CC         CO2 + Na(+)(out); Xref=Rhea:RHEA:23972, ChEBI:CHEBI:15378,
CC         ChEBI:CHEBI:16526, ChEBI:CHEBI:29101, ChEBI:CHEBI:57332,
CC         ChEBI:CHEBI:57353; EC=7.2.4.5;
CC   -!- PATHWAY: Amino-acid degradation; L-glutamate degradation via
CC       hydroxyglutarate pathway; crotonoyl-CoA from L-glutamate: step 5/5.
CC   -!- SUBUNIT: Heterooctamer consisting of two alpha, two beta, two gamma and
CC       two delta subunits.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000250}; Single-pass membrane
CC       protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the OadG family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AF030576; AAC69171.1; -; Genomic_DNA.
DR   EMBL; CP001859; ADB48190.1; -; Genomic_DNA.
DR   RefSeq; WP_012939173.1; NC_013740.1.
DR   AlphaFoldDB; Q9ZAA8; -.
DR   SMR; Q9ZAA8; -.
DR   STRING; 591001.Acfer_1836; -.
DR   TCDB; 3.B.1.1.3; the na(+)-transporting carboxylic acid decarboxylase (nat-dc) family.
DR   EnsemblBacteria; ADB48190; ADB48190; Acfer_1836.
DR   KEGG; afn:Acfer_1836; -.
DR   HOGENOM; CLU_170325_0_0_9; -.
DR   OMA; IIMLINM; -.
DR   BioCyc; MetaCyc:MON-1057; -.
DR   BRENDA; 7.2.4.5; 85.
DR   SABIO-RK; Q9ZAA8; -.
DR   UniPathway; UPA00533; UER00688.
DR   Proteomes; UP000001902; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0018801; F:glutaconyl-CoA decarboxylase activity; IEA:UniProtKB-EC.
DR   GO; GO:0015081; F:sodium ion transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0019552; P:glutamate catabolic process via 2-hydroxyglutarate; IEA:UniProtKB-UniPathway.
DR   GO; GO:0036376; P:sodium ion export across plasma membrane; IEA:InterPro.
DR   InterPro; IPR005899; Na_pump_deCOase.
DR   Pfam; PF04277; OAD_gamma; 1.
DR   TIGRFAMs; TIGR01195; oadG_fam; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Decarboxylase; Ion transport; Lyase; Membrane;
KW   Reference proteome; Sodium; Sodium transport; Translocase; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..107
FT                   /note="Glutaconyl-CoA decarboxylase subunit delta"
FT                   /id="PRO_0000216466"
FT   TRANSMEM        10..32
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          37..60
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   107 AA;  11624 MW;  7B363CF48D435C82 CRC64;
     MTDNPWLIMM INMTIVFGVL IVLGILMVLI HAVDPTKKVQ GKKKPVVAKP APSAAASKRQ
     EEEKVAAMAA VLALVQDEDD MIAAALSAAI AEHKRKMEPM NLPHHSF