ID   GCH1L_LACLA             Reviewed;         257 AA.
AC   Q9CGM3;
DT   15-MAY-2002, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2001, sequence version 1.
DT   03-AUG-2022, entry version 93.
DE   RecName: Full=GTP cyclohydrolase 1 type 2 homolog;
GN   Name=ykiD; OrderedLocusNames=LL1073; ORFNames=L84937;
OS   Lactococcus lactis subsp. lactis (strain IL1403) (Streptococcus lactis).
OC   Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae;
OC   Lactococcus.
OX   NCBI_TaxID=272623;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=IL1403;
RX   PubMed=11337471; DOI=10.1101/gr.gr-1697r;
RA   Bolotin A., Wincker P., Mauger S., Jaillon O., Malarme K., Weissenbach J.,
RA   Ehrlich S.D., Sorokin A.;
RT   "The complete genome sequence of the lactic acid bacterium Lactococcus
RT   lactis ssp. lactis IL1403.";
RL   Genome Res. 11:731-753(2001).
CC   -!- SUBUNIT: Homohexamer. {ECO:0000250|UniProtKB:P0AFP6}.
CC   -!- SIMILARITY: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.
CC       {ECO:0000305}.
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DR   EMBL; AE005176; AAK05171.1; -; Genomic_DNA.
DR   PIR; A86759; A86759.
DR   RefSeq; NP_267229.1; NC_002662.1.
DR   RefSeq; WP_010905742.1; NC_002662.1.
DR   AlphaFoldDB; Q9CGM3; -.
DR   SMR; Q9CGM3; -.
DR   STRING; 272623.L84937; -.
DR   PaxDb; Q9CGM3; -.
DR   EnsemblBacteria; AAK05171; AAK05171; L84937.
DR   KEGG; lla:L84937; -.
DR   PATRIC; fig|272623.7.peg.1151; -.
DR   eggNOG; COG0327; Bacteria.
DR   HOGENOM; CLU_037423_2_0_9; -.
DR   OMA; ISMHTNF; -.
DR   Proteomes; UP000002196; Chromosome.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   InterPro; IPR002678; DUF34/NIF3.
DR   InterPro; IPR036069; DUF34/NIF3_sf.
DR   PANTHER; PTHR13799; PTHR13799; 1.
DR   Pfam; PF01784; NIF3; 1.
DR   SUPFAM; SSF102705; SSF102705; 1.
DR   TIGRFAMs; TIGR00486; YbgI_SA1388; 1.
PE   3: Inferred from homology;
KW   Metal-binding; Reference proteome.
FT   CHAIN           1..257
FT                   /note="GTP cyclohydrolase 1 type 2 homolog"
FT                   /id="PRO_0000147313"
FT   BINDING         65
FT                   /ligand="a divalent metal cation"
FT                   /ligand_id="ChEBI:CHEBI:60240"
FT                   /ligand_label="2"
FT                   /evidence="ECO:0000250|UniProtKB:P0AFP6"
FT   BINDING         103
FT                   /ligand="a divalent metal cation"
FT                   /ligand_id="ChEBI:CHEBI:60240"
FT                   /ligand_label="1"
FT                   /evidence="ECO:0000250|UniProtKB:P0AFP6"
FT   BINDING         221
FT                   /ligand="a divalent metal cation"
FT                   /ligand_id="ChEBI:CHEBI:60240"
FT                   /ligand_label="2"
FT                   /evidence="ECO:0000250|UniProtKB:P0AFP6"
FT   BINDING         224
FT                   /ligand="a divalent metal cation"
FT                   /ligand_id="ChEBI:CHEBI:60240"
FT                   /ligand_label="1"
FT                   /evidence="ECO:0000250|UniProtKB:P0AFP6"
FT   BINDING         224
FT                   /ligand="a divalent metal cation"
FT                   /ligand_id="ChEBI:CHEBI:60240"
FT                   /ligand_label="2"
FT                   /evidence="ECO:0000250|UniProtKB:P0AFP6"
SQ   SEQUENCE   257 AA;  28468 MW;  B89B74F65541191A CRC64;
     MKISDFMLEY EKFCPKELAV EGDPVGLQVG NPNDELTKVL VTLDIREQTV AEAKALGVNL
     IIAKHPLIFR PLSALTSMND QEKLVLDLAR AGIAVYTSHT NIDVVTGGLN DYFSQLLGMT
     DIEVLDDEEG LGRVGNIELT ELSVLTEKVK ASFGLDRLRL ITYDHNLTQK IGRIAICGGS
     GGKLWPKALE KKADIYITGD IYYHVGHDML SAGLLGIDPG HYIEHAFIRL VADKLRSFDM
     GVKIYESQEK TNPFYDI