ID   GCH1L_LISMO             Reviewed;         373 AA.
AC   P53434;
DT   01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1996, sequence version 1.
DT   03-AUG-2022, entry version 109.
DE   RecName: Full=GTP cyclohydrolase 1 type 2 homolog;
GN   OrderedLocusNames=lmo1452;
OS   Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Listeriaceae; Listeria.
OX   NCBI_TaxID=169963;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=LO28 / Serovar 1/2c;
RA   Klarsfeld A.D., Cossart P.;
RL   Submitted (MAR-1995) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-679 / EGD-e;
RX   PubMed=11679669; DOI=10.1126/science.1063447;
RA   Glaser P., Frangeul L., Buchrieser C., Rusniok C., Amend A., Baquero F.,
RA   Berche P., Bloecker H., Brandt P., Chakraborty T., Charbit A.,
RA   Chetouani F., Couve E., de Daruvar A., Dehoux P., Domann E.,
RA   Dominguez-Bernal G., Duchaud E., Durant L., Dussurget O., Entian K.-D.,
RA   Fsihi H., Garcia-del Portillo F., Garrido P., Gautier L., Goebel W.,
RA   Gomez-Lopez N., Hain T., Hauf J., Jackson D., Jones L.-M., Kaerst U.,
RA   Kreft J., Kuhn M., Kunst F., Kurapkat G., Madueno E., Maitournam A.,
RA   Mata Vicente J., Ng E., Nedjari H., Nordsiek G., Novella S., de Pablos B.,
RA   Perez-Diaz J.-C., Purcell R., Remmel B., Rose M., Schlueter T., Simoes N.,
RA   Tierrez A., Vazquez-Boland J.-A., Voss H., Wehland J., Cossart P.;
RT   "Comparative genomics of Listeria species.";
RL   Science 294:849-852(2001).
CC   -!- SUBUNIT: Homohexamer. {ECO:0000250|UniProtKB:P0AFP6}.
CC   -!- SIMILARITY: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.
CC       {ECO:0000305}.
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DR   EMBL; U17284; AAA62502.1; -; Genomic_DNA.
DR   EMBL; AL591979; CAC99530.1; -; Genomic_DNA.
DR   PIR; AD1256; AD1256.
DR   RefSeq; NP_464977.1; NC_003210.1.
DR   RefSeq; WP_010990128.1; NZ_CP023861.1.
DR   AlphaFoldDB; P53434; -.
DR   SMR; P53434; -.
DR   STRING; 169963.lmo1452; -.
DR   PaxDb; P53434; -.
DR   EnsemblBacteria; CAC99530; CAC99530; CAC99530.
DR   GeneID; 986883; -.
DR   KEGG; lmo:lmo1452; -.
DR   PATRIC; fig|169963.11.peg.1491; -.
DR   eggNOG; COG0327; Bacteria.
DR   HOGENOM; CLU_037423_1_0_9; -.
DR   OMA; EVAYDIY; -.
DR   PhylomeDB; P53434; -.
DR   BioCyc; LMON169963:LMO1452-MON; -.
DR   Proteomes; UP000000817; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.70.120; -; 1.
DR   InterPro; IPR002678; DUF34/NIF3.
DR   InterPro; IPR017221; DUF34/NIF3_bac.
DR   InterPro; IPR036069; DUF34/NIF3_sf.
DR   InterPro; IPR015867; N-reg_PII/ATP_PRibTrfase_C.
DR   PANTHER; PTHR13799; PTHR13799; 1.
DR   Pfam; PF01784; NIF3; 1.
DR   PIRSF; PIRSF037489; UCP037489_NIF3_YqfO; 1.
DR   SUPFAM; SSF102705; SSF102705; 1.
DR   TIGRFAMs; TIGR00486; YbgI_SA1388; 1.
PE   3: Inferred from homology;
KW   Metal-binding; Reference proteome.
FT   CHAIN           1..373
FT                   /note="GTP cyclohydrolase 1 type 2 homolog"
FT                   /id="PRO_0000147315"
FT   BINDING         67
FT                   /ligand="a divalent metal cation"
FT                   /ligand_id="ChEBI:CHEBI:60240"
FT                   /ligand_label="1"
FT                   /evidence="ECO:0000250|UniProtKB:P0AFP6"
FT   BINDING         68
FT                   /ligand="a divalent metal cation"
FT                   /ligand_id="ChEBI:CHEBI:60240"
FT                   /ligand_label="2"
FT                   /evidence="ECO:0000250|UniProtKB:P0AFP6"
FT   BINDING         106
FT                   /ligand="a divalent metal cation"
FT                   /ligand_id="ChEBI:CHEBI:60240"
FT                   /ligand_label="1"
FT                   /evidence="ECO:0000250|UniProtKB:P0AFP6"
FT   BINDING         333
FT                   /ligand="a divalent metal cation"
FT                   /ligand_id="ChEBI:CHEBI:60240"
FT                   /ligand_label="2"
FT                   /evidence="ECO:0000250|UniProtKB:P0AFP6"
FT   BINDING         336
FT                   /ligand="a divalent metal cation"
FT                   /ligand_id="ChEBI:CHEBI:60240"
FT                   /ligand_label="1"
FT                   /evidence="ECO:0000250|UniProtKB:P0AFP6"
FT   BINDING         336
FT                   /ligand="a divalent metal cation"
FT                   /ligand_id="ChEBI:CHEBI:60240"
FT                   /ligand_label="2"
FT                   /evidence="ECO:0000250|UniProtKB:P0AFP6"
SQ   SEQUENCE   373 AA;  41433 MW;  C79AF8A87E2369A2 CRC64;
     MKVANGYEYT AIMEKIAPKK LAMEGDPIGL QVGDLSRKVR KIMFTLDVLE EVVDEAIEKK
     VDLIIAHHPF LYRPTQHIDT TTKQGKMIKK LIKHDITVFA AHTNLDIAQG GVNNILADLL
     HLQNTTMIEE TYSEPYCKIA VYVPENELES VRLALVNNGA GQIGTEYTEC TFHTTGIGSF
     KPGANANPTI GEKDALTSVP EVKIEAIFPQ YLTETITKAV KIAHPYEEPA IDVYTLEMQT
     YKEGLGRVGM LPKKLGMVSF IDKLKTAFAI DNVRFIGDLK TTVHKVAIIG GDGNKFIHQA
     KSTGADVFIT GDVYYHTGHD LLAINLPTID AGHNIEKVMK GYLKNKMEEQ AKILDYEAEF
     IVSEVNTDPF QFC