GCH1L_PSEAE
ID GCH1L_PSEAE Reviewed; 252 AA.
AC Q9HVX2;
DT 15-MAY-2002, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2001, sequence version 1.
DT 03-AUG-2022, entry version 92.
DE RecName: Full=GTP cyclohydrolase 1 type 2 homolog;
GN OrderedLocusNames=PA4445;
OS Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM
OS 14847 / LMG 12228 / 1C / PRS 101 / PAO1).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC Pseudomonadaceae; Pseudomonas.
OX NCBI_TaxID=208964;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C /
RC PRS 101 / PAO1;
RX PubMed=10984043; DOI=10.1038/35023079;
RA Stover C.K., Pham X.-Q.T., Erwin A.L., Mizoguchi S.D., Warrener P.,
RA Hickey M.J., Brinkman F.S.L., Hufnagle W.O., Kowalik D.J., Lagrou M.,
RA Garber R.L., Goltry L., Tolentino E., Westbrock-Wadman S., Yuan Y.,
RA Brody L.L., Coulter S.N., Folger K.R., Kas A., Larbig K., Lim R.M.,
RA Smith K.A., Spencer D.H., Wong G.K.-S., Wu Z., Paulsen I.T., Reizer J.,
RA Saier M.H. Jr., Hancock R.E.W., Lory S., Olson M.V.;
RT "Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic
RT pathogen.";
RL Nature 406:959-964(2000).
CC -!- SUBUNIT: Homohexamer. {ECO:0000250|UniProtKB:P0AFP6}.
CC -!- SIMILARITY: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.
CC {ECO:0000305}.
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DR EMBL; AE004091; AAG07833.1; -; Genomic_DNA.
DR PIR; A83089; A83089.
DR RefSeq; NP_253135.1; NC_002516.2.
DR RefSeq; WP_003094318.1; NZ_QZGE01000004.1.
DR AlphaFoldDB; Q9HVX2; -.
DR SMR; Q9HVX2; -.
DR STRING; 287.DR97_1622; -.
DR PaxDb; Q9HVX2; -.
DR PRIDE; Q9HVX2; -.
DR EnsemblBacteria; AAG07833; AAG07833; PA4445.
DR GeneID; 880975; -.
DR KEGG; pae:PA4445; -.
DR PATRIC; fig|208964.12.peg.4654; -.
DR PseudoCAP; PA4445; -.
DR HOGENOM; CLU_037423_3_0_6; -.
DR InParanoid; Q9HVX2; -.
DR OMA; HGLFWRG; -.
DR PhylomeDB; Q9HVX2; -.
DR BioCyc; PAER208964:G1FZ6-4533-MON; -.
DR Proteomes; UP000002438; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR InterPro; IPR002678; DUF34/NIF3.
DR InterPro; IPR036069; DUF34/NIF3_sf.
DR PANTHER; PTHR13799; PTHR13799; 1.
DR Pfam; PF01784; NIF3; 1.
DR SUPFAM; SSF102705; SSF102705; 1.
DR TIGRFAMs; TIGR00486; YbgI_SA1388; 1.
PE 3: Inferred from homology;
KW Metal-binding; Reference proteome.
FT CHAIN 1..252
FT /note="GTP cyclohydrolase 1 type 2 homolog"
FT /id="PRO_0000147323"
FT BINDING 65
FT /ligand="a divalent metal cation"
FT /ligand_id="ChEBI:CHEBI:60240"
FT /ligand_label="1"
FT /evidence="ECO:0000250|UniProtKB:P0AFP6"
FT BINDING 66
FT /ligand="a divalent metal cation"
FT /ligand_id="ChEBI:CHEBI:60240"
FT /ligand_label="2"
FT /evidence="ECO:0000250|UniProtKB:P0AFP6"
FT BINDING 103
FT /ligand="a divalent metal cation"
FT /ligand_id="ChEBI:CHEBI:60240"
FT /ligand_label="1"
FT /evidence="ECO:0000250|UniProtKB:P0AFP6"
FT BINDING 220
FT /ligand="a divalent metal cation"
FT /ligand_id="ChEBI:CHEBI:60240"
FT /ligand_label="2"
FT /evidence="ECO:0000250|UniProtKB:P0AFP6"
FT BINDING 224
FT /ligand="a divalent metal cation"
FT /ligand_id="ChEBI:CHEBI:60240"
FT /ligand_label="1"
FT /evidence="ECO:0000250|UniProtKB:P0AFP6"
FT BINDING 224
FT /ligand="a divalent metal cation"
FT /ligand_id="ChEBI:CHEBI:60240"
FT /ligand_label="2"
FT /evidence="ECO:0000250|UniProtKB:P0AFP6"
SQ SEQUENCE 252 AA; 27360 MW; 69123E1861F7D4C8 CRC64;
MAIALSTLVE EADRYLDAAR IQDYCPNGLQ VEGRPQVRRI VSGVTASQAL LDAAVEADAD
VVLVHHGYFW KGENPCVVGM KQRRLKTLLN NDISLLAYHL PLDLHPEVGN NVQLARQLGF
EVEGPLEPGN PRSIVLLGSL AEPMQPADFA RHVRDALGRE PLLVDAGQPI RRIAWCTGGA
QGYIDQAIAA GVDAYLTGEV SEQTVHSARE NGISFIAAGH HATERYGVQA LGDYLGKRFA
IEHLFIDCPN PA
