ID   GCP4_MEDTR              Reviewed;         739 AA.
AC   Q9SC88;
DT   02-AUG-2002, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-2000, sequence version 1.
DT   25-MAY-2022, entry version 79.
DE   RecName: Full=Gamma-tubulin complex component 4 homolog;
GN   Name=85P;
OS   Medicago truncatula (Barrel medic) (Medicago tribuloides).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC   NPAAA clade; Hologalegina; IRL clade; Trifolieae; Medicago.
OX   NCBI_TaxID=3880;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RX   PubMed=10562286; DOI=10.1083/jcb.147.4.857;
RA   Fava F., Raynaud-Messina B., Leung-Tack J., Mazzolini L., Li M.,
RA   Guillemot J.-C., Cachot D., Tollon Y., Ferrara P., Wright M.;
RT   "Human 76p: a new protein member of the gamma-tubulin associated protein
RT   family.";
RL   J. Cell Biol. 147:857-868(1999).
CC   -!- FUNCTION: Gamma-tubulin complex is necessary for microtubule nucleation
CC       at the microtubule organizing centers (MTOCs). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, microtubule organizing
CC       center {ECO:0000250|UniProtKB:Q9BSJ2}.
CC   -!- SIMILARITY: Belongs to the TUBGCP family. {ECO:0000305}.
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DR   EMBL; AJ249679; CAB62542.1; -; mRNA.
DR   RefSeq; XP_003591513.2; XM_003591465.2.
DR   AlphaFoldDB; Q9SC88; -.
DR   SMR; Q9SC88; -.
DR   STRING; 3880.AES61764; -.
DR   PRIDE; Q9SC88; -.
DR   EnsemblPlants; AES61764; AES61764; MTR_1g088410.
DR   GeneID; 11416818; -.
DR   Gramene; AES61764; AES61764; MTR_1g088410.
DR   eggNOG; KOG2065; Eukaryota.
DR   HOGENOM; CLU_012029_0_0_1; -.
DR   OrthoDB; 1137416at2759; -.
DR   ExpressionAtlas; Q9SC88; differential.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR   GO; GO:0005815; C:microtubule organizing center; IEA:InterPro.
DR   GO; GO:0000922; C:spindle pole; IEA:InterPro.
DR   GO; GO:0045298; C:tubulin complex; IEA:EnsemblPlants.
DR   GO; GO:0043015; F:gamma-tubulin binding; IEA:InterPro.
DR   GO; GO:0043622; P:cortical microtubule organization; IEA:EnsemblPlants.
DR   GO; GO:0007020; P:microtubule nucleation; IEA:EnsemblPlants.
DR   GO; GO:0009624; P:response to nematode; IEA:EnsemblPlants.
DR   Gene3D; 1.20.120.1900; -; 1.
DR   InterPro; IPR007259; GCP.
DR   InterPro; IPR040457; GCP_C.
DR   InterPro; IPR042241; GCP_C_sf.
DR   InterPro; IPR041470; GCP_N.
DR   PANTHER; PTHR19302; PTHR19302; 1.
DR   Pfam; PF04130; GCP_C_terminal; 1.
DR   Pfam; PF17681; GCP_N_terminal; 1.
PE   2: Evidence at transcript level;
KW   Cytoplasm; Cytoskeleton; Microtubule.
FT   CHAIN           1..739
FT                   /note="Gamma-tubulin complex component 4 homolog"
FT                   /id="PRO_0000078128"
SQ   SEQUENCE   739 AA;  85275 MW;  78CC771C4C63059E CRC64;
     MLHELLLALL GYTGDLIIDR RDNNLSANTP ISDECTFKLA PDISFIDPSD RELIERIITL
     GFYYRELERF SAKSRNLNWI RSENANPLEN KEKPSVYRRA LANGIVEILA VYSSSILHIE
     QLLLSETMPI LATVTQGLNK FFSLLPPLYE LILKIERGDI RGGELLNLLH KKCHCGVPEL
     QTCIQRLLWH GHQVMYNQLA SWMVYGILED RHGEFFISRQ EGRDVENSSS HQEISEKLSR
     LSTADASLSD WHMGFHISLD MLPEYIPMRV AESILFAGKA VRVLRNPSPS FLSQDDVYPQ
     EPKRFPKIHG FEGRFNFQRE PIINTGMRVE DLLPQSEADK IENMLLDLKE SSEFHKRSFE
     CAVDSIQAIA ASHLWQLVVV RADLNGHLKA LKDYFLLAKG DFFQCFLEES RQLMRLPPRQ
     STAEADLMVP FQLASLKTIG EEDKYFSKVS LRMPSYGITV KPSLLNVPKA TSAAADGISG
     ASISNASSEM SVDGWDGIAL EYSIEWPLHL FFTQEVLSRY LKVFQYLLRL KRTQMELEKL
     WASVMHQYHS IFAKNKKSDQ DKSPITQQRD QRFRSMWRVR EHMAFLIRNL QFYIQVDVIE
     SQWNILQSHI QDSHDFTELV GFHQEYLSAL ISQTFLDIGS VSRILDGIMK LCLQFCWNIE
     NQDNFSNTSE LEHIAEEFNK KSNSLYTILR SSRLAGSQRT PFLRRFLLRL NLNSFFESTA
     KEVMNVVRPR PTFPGLNQR