ID   ALLC2_DELRA             Reviewed;          15 AA.
AC   B3EWJ6;
DT   03-OCT-2012, integrated into UniProtKB/Swiss-Prot.
DT   03-OCT-2012, sequence version 1.
DT   02-JUN-2021, entry version 10.
DE   RecName: Full=Allatostatin-C2;
DE            Short=AST-C2;
OS   Delia radicum (Cabbage root fly) (Anthomyia brassicae).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Muscoidea;
OC   Anthomyiidae; Anthomyiinae; Delia.
OX   NCBI_TaxID=30064;
RN   [1] {ECO:0000305}
RP   PROTEIN SEQUENCE, TISSUE SPECIFICITY, DEVELOPMENTAL STAGE, AND MASS
RP   SPECTROMETRY.
RC   TISSUE=CNS {ECO:0000269|PubMed:22848525}, and
RC   Midgut {ECO:0000269|PubMed:22848525};
RX   PubMed=22848525; DOI=10.1371/journal.pone.0041543;
RA   Zoephel J., Reiher W., Rexer K.-H., Kahnt J., Wegener C.;
RT   "Peptidomics of the agriculturally damaging larval stage of the cabbage
RT   root fly Delia radicum (Diptera: Anthomyiidae).";
RL   PLoS ONE 7:E41543-E41543(2012).
CC   -!- FUNCTION: Strongly inhibits juvenile hormone biosynthesis. May act as a
CC       neurotransmitter or neuromodulator (By similarity).
CC       {ECO:0000250|UniProtKB:P42559}.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250|UniProtKB:P42559}.
CC   -!- TISSUE SPECIFICITY: Expressed in the CNS and midgut but not in the ring
CC       gland, thoracic perisymapthetic organs (tPSO) or abdominal
CC       perisymapthetic organs (aPSO) (at protein level).
CC       {ECO:0000269|PubMed:22848525}.
CC   -!- DEVELOPMENTAL STAGE: Detected in larvae. {ECO:0000269|PubMed:22848525}.
CC   -!- MASS SPECTROMETRY: Mass=1921.87; Method=MALDI;
CC       Evidence={ECO:0000269|PubMed:22848525};
CC   -!- SIMILARITY: Belongs to the allatostatin family. {ECO:0000255}.
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DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0007218; P:neuropeptide signaling pathway; IEA:UniProtKB-KW.
PE   1: Evidence at protein level;
KW   Direct protein sequencing; Disulfide bond; Neuropeptide; Secreted.
FT   PEPTIDE         1..15
FT                   /note="Allatostatin-C2"
FT                   /id="PRO_0000419716"
FT   DISULFID        7..14
FT                   /evidence="ECO:0000269|PubMed:22848525"
FT   UNSURE          12
FT                   /note="I or L"
FT                   /evidence="ECO:0000269|PubMed:22848525"
SQ   SEQUENCE   15 AA;  1924 MW;  1605B7647DBC838E CRC64;
     QVRYRQCYFN PISCF