ID   GCSHL_CHLMU             Reviewed;         117 AA.
AC   Q9PKB2;
DT   01-DEC-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2000, sequence version 1.
DT   25-MAY-2022, entry version 120.
DE   RecName: Full=Glycine cleavage system H-like protein {ECO:0000305};
GN   Name=gcvH {ECO:0000312|EMBL:AAF39393.1}; OrderedLocusNames=TC_0554;
OS   Chlamydia muridarum (strain MoPn / Nigg).
OC   Bacteria; Chlamydiae; Chlamydiales; Chlamydiaceae;
OC   Chlamydia/Chlamydophila group; Chlamydia.
OX   NCBI_TaxID=243161;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MoPn / Nigg;
RX   PubMed=10684935; DOI=10.1093/nar/28.6.1397;
RA   Read T.D., Brunham R.C., Shen C., Gill S.R., Heidelberg J.F., White O.,
RA   Hickey E.K., Peterson J.D., Utterback T.R., Berry K.J., Bass S.,
RA   Linher K.D., Weidman J.F., Khouri H.M., Craven B., Bowman C., Dodson R.J.,
RA   Gwinn M.L., Nelson W.C., DeBoy R.T., Kolonay J.F., McClarty G.,
RA   Salzberg S.L., Eisen J.A., Fraser C.M.;
RT   "Genome sequences of Chlamydia trachomatis MoPn and Chlamydia pneumoniae
RT   AR39.";
RL   Nucleic Acids Res. 28:1397-1406(2000).
CC   -!- COFACTOR:
CC       Name=(R)-lipoate; Xref=ChEBI:CHEBI:83088;
CC         Evidence={ECO:0000255|PROSITE-ProRule:PRU01066};
CC       Note=Binds 1 lipoyl cofactor covalently. {ECO:0000255|PROSITE-
CC       ProRule:PRU01066};
CC   -!- SIMILARITY: Belongs to the GcvH family. {ECO:0000305}.
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DR   EMBL; AE002160; AAF39393.1; -; Genomic_DNA.
DR   PIR; F81690; F81690.
DR   RefSeq; WP_010230826.1; NZ_CP027217.1.
DR   AlphaFoldDB; Q9PKB2; -.
DR   SMR; Q9PKB2; -.
DR   STRING; 243161.TC_0554; -.
DR   EnsemblBacteria; AAF39393; AAF39393; TC_0554.
DR   GeneID; 1245914; -.
DR   KEGG; cmu:TC_0554; -.
DR   eggNOG; COG0509; Bacteria.
DR   HOGENOM; CLU_097408_2_4_0; -.
DR   OMA; EHEWLSG; -.
DR   OrthoDB; 1773485at2; -.
DR   Proteomes; UP000000800; Chromosome.
DR   GO; GO:0005960; C:glycine cleavage complex; IEA:InterPro.
DR   GO; GO:0019464; P:glycine decarboxylation via glycine cleavage system; IEA:InterPro.
DR   CDD; cd06848; GCS_H; 1.
DR   InterPro; IPR003016; 2-oxoA_DH_lipoyl-BS.
DR   InterPro; IPR000089; Biotin_lipoyl.
DR   InterPro; IPR002930; GCV_H.
DR   InterPro; IPR033753; GCV_H/Fam206.
DR   InterPro; IPR017514; GcvH_Chlamydia.
DR   InterPro; IPR011053; Single_hybrid_motif.
DR   PANTHER; PTHR11715; PTHR11715; 1.
DR   Pfam; PF01597; GCV_H; 1.
DR   SUPFAM; SSF51230; SSF51230; 1.
DR   TIGRFAMs; TIGR03077; not_gcvH; 1.
DR   PROSITE; PS50968; BIOTINYL_LIPOYL; 1.
DR   PROSITE; PS00189; LIPOYL; 1.
PE   3: Inferred from homology;
KW   Lipoyl.
FT   CHAIN           1..117
FT                   /note="Glycine cleavage system H-like protein"
FT                   /id="PRO_0000166212"
FT   DOMAIN          21..103
FT                   /note="Lipoyl-binding"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01066"
FT   MOD_RES         62
FT                   /note="N6-lipoyllysine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01066"
SQ   SEQUENCE   117 AA;  13088 MW;  DD71455BAD0C2F39 CRC64;
     MKGKKYYSDY HVWIEPIHSQ IVRLGLSSRM QEHLGNILHI DLPSLGASIK EGEELCVLES
     SKSAIEVLSP VSGEVIEVNI ALEDDTHPIN HSAESEGWFV VLQLSEDFDG ERFSLDP