ID   GCSHL_CHLPN             Reviewed;         115 AA.
AC   Q9Z8B0;
DT   01-DEC-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-1999, sequence version 1.
DT   25-MAY-2022, entry version 135.
DE   RecName: Full=Glycine cleavage system H-like protein {ECO:0000305};
GN   Name=gcsH {ECO:0000312|EMBL:BAA98641.1};
GN   OrderedLocusNames=CPn_0433, CP_0320, CpB0449;
OS   Chlamydia pneumoniae (Chlamydophila pneumoniae).
OC   Bacteria; Chlamydiae; Chlamydiales; Chlamydiaceae;
OC   Chlamydia/Chlamydophila group; Chlamydia.
OX   NCBI_TaxID=83558;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CWL029;
RX   PubMed=10192388; DOI=10.1038/7716;
RA   Kalman S., Mitchell W.P., Marathe R., Lammel C.J., Fan J., Hyman R.W.,
RA   Olinger L., Grimwood J., Davis R.W., Stephens R.S.;
RT   "Comparative genomes of Chlamydia pneumoniae and C. trachomatis.";
RL   Nat. Genet. 21:385-389(1999).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AR39;
RX   PubMed=10684935; DOI=10.1093/nar/28.6.1397;
RA   Read T.D., Brunham R.C., Shen C., Gill S.R., Heidelberg J.F., White O.,
RA   Hickey E.K., Peterson J.D., Utterback T.R., Berry K.J., Bass S.,
RA   Linher K.D., Weidman J.F., Khouri H.M., Craven B., Bowman C., Dodson R.J.,
RA   Gwinn M.L., Nelson W.C., DeBoy R.T., Kolonay J.F., McClarty G.,
RA   Salzberg S.L., Eisen J.A., Fraser C.M.;
RT   "Genome sequences of Chlamydia trachomatis MoPn and Chlamydia pneumoniae
RT   AR39.";
RL   Nucleic Acids Res. 28:1397-1406(2000).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=J138;
RX   PubMed=10871362; DOI=10.1093/nar/28.12.2311;
RA   Shirai M., Hirakawa H., Kimoto M., Tabuchi M., Kishi F., Ouchi K.,
RA   Shiba T., Ishii K., Hattori M., Kuhara S., Nakazawa T.;
RT   "Comparison of whole genome sequences of Chlamydia pneumoniae J138 from
RT   Japan and CWL029 from USA.";
RL   Nucleic Acids Res. 28:2311-2314(2000).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=TW-183;
RA   Geng M.M., Schuhmacher A., Muehldorfer I., Bensch K.W., Schaefer K.P.,
RA   Schneider S., Pohl T., Essig A., Marre R., Melchers K.;
RT   "The genome sequence of Chlamydia pneumoniae TW183 and comparison with
RT   other Chlamydia strains based on whole genome sequence analysis.";
RL   Submitted (MAY-2002) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=(R)-lipoate; Xref=ChEBI:CHEBI:83088;
CC         Evidence={ECO:0000255|PROSITE-ProRule:PRU01066};
CC       Note=Binds 1 lipoyl cofactor covalently. {ECO:0000255|PROSITE-
CC       ProRule:PRU01066};
CC   -!- SIMILARITY: Belongs to the GcvH family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAP98380.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; AE001363; AAD18577.1; -; Genomic_DNA.
DR   EMBL; AE002161; AAF38175.1; -; Genomic_DNA.
DR   EMBL; BA000008; BAA98641.1; -; Genomic_DNA.
DR   EMBL; AE009440; AAP98380.1; ALT_INIT; Genomic_DNA.
DR   PIR; C72079; C72079.
DR   PIR; G86544; G86544.
DR   RefSeq; NP_224633.1; NC_000922.1.
DR   RefSeq; WP_010883076.1; NZ_LN847257.1.
DR   AlphaFoldDB; Q9Z8B0; -.
DR   SMR; Q9Z8B0; -.
DR   STRING; 115711.CP_0320; -.
DR   EnsemblBacteria; AAD18577; AAD18577; CPn_0433.
DR   EnsemblBacteria; AAF38175; AAF38175; CP_0320.
DR   GeneID; 45050480; -.
DR   KEGG; cpa:CP_0320; -.
DR   KEGG; cpj:gcsH; -.
DR   KEGG; cpn:CPn_0433; -.
DR   KEGG; cpt:CpB0449; -.
DR   PATRIC; fig|115713.3.peg.480; -.
DR   eggNOG; COG0509; Bacteria.
DR   HOGENOM; CLU_097408_2_4_0; -.
DR   OMA; EHEWLSG; -.
DR   OrthoDB; 1773485at2; -.
DR   Proteomes; UP000000583; Chromosome.
DR   Proteomes; UP000000801; Chromosome.
DR   GO; GO:0005960; C:glycine cleavage complex; IEA:InterPro.
DR   GO; GO:0019464; P:glycine decarboxylation via glycine cleavage system; IEA:InterPro.
DR   CDD; cd06848; GCS_H; 1.
DR   InterPro; IPR000089; Biotin_lipoyl.
DR   InterPro; IPR002930; GCV_H.
DR   InterPro; IPR033753; GCV_H/Fam206.
DR   InterPro; IPR017514; GcvH_Chlamydia.
DR   InterPro; IPR011053; Single_hybrid_motif.
DR   PANTHER; PTHR11715; PTHR11715; 1.
DR   Pfam; PF01597; GCV_H; 1.
DR   SUPFAM; SSF51230; SSF51230; 1.
DR   TIGRFAMs; TIGR03077; not_gcvH; 1.
DR   PROSITE; PS50968; BIOTINYL_LIPOYL; 1.
PE   3: Inferred from homology;
KW   Lipoyl.
FT   CHAIN           1..115
FT                   /note="Glycine cleavage system H-like protein"
FT                   /id="PRO_0000166213"
FT   DOMAIN          17..99
FT                   /note="Lipoyl-binding"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01066"
FT   MOD_RES         58
FT                   /note="N6-lipoyllysine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01066"
SQ   SEQUENCE   115 AA;  12876 MW;  43FF43363A48D175 CRC64;
     MWYSDYHVWI LPVHERVVRL GLTEKMQKNL GAILHVDLPS VGSLCKEGEV LVILESSKSA
     IEVLSPVSGE VIDINLDLVD NPQKINEAPE GEGWLAVVRL DQDWDPSNLS LMDEE