ID   GCSHL_CHLTA             Reviewed;         117 AA.
AC   Q3KM80;
DT   11-SEP-2007, integrated into UniProtKB/Swiss-Prot.
DT   08-NOV-2005, sequence version 1.
DT   25-MAY-2022, entry version 91.
DE   RecName: Full=Glycine cleavage system H-like protein {ECO:0000305};
GN   Name=gcsH {ECO:0000312|EMBL:AAX50542.1}; OrderedLocusNames=CTA_0304;
OS   Chlamydia trachomatis serovar A (strain ATCC VR-571B / DSM 19440 / HAR-13).
OC   Bacteria; Chlamydiae; Chlamydiales; Chlamydiaceae;
OC   Chlamydia/Chlamydophila group; Chlamydia.
OX   NCBI_TaxID=315277;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC VR-571B / DSM 19440 / HAR-13;
RX   PubMed=16177312; DOI=10.1128/iai.73.10.6407-6418.2005;
RA   Carlson J.H., Porcella S.F., McClarty G., Caldwell H.D.;
RT   "Comparative genomic analysis of Chlamydia trachomatis oculotropic and
RT   genitotropic strains.";
RL   Infect. Immun. 73:6407-6418(2005).
CC   -!- COFACTOR:
CC       Name=(R)-lipoate; Xref=ChEBI:CHEBI:83088;
CC         Evidence={ECO:0000255|PROSITE-ProRule:PRU01066};
CC       Note=Binds 1 lipoyl cofactor covalently. {ECO:0000255|PROSITE-
CC       ProRule:PRU01066};
CC   -!- SIMILARITY: Belongs to the GcvH family. {ECO:0000305}.
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DR   EMBL; CP000051; AAX50542.1; -; Genomic_DNA.
DR   RefSeq; WP_009871629.1; NC_007429.1.
DR   AlphaFoldDB; Q3KM80; -.
DR   SMR; Q3KM80; -.
DR   EnsemblBacteria; AAX50542; AAX50542; CTA_0304.
DR   KEGG; cta:CTA_0304; -.
DR   HOGENOM; CLU_097408_2_4_0; -.
DR   OMA; EHEWLSG; -.
DR   Proteomes; UP000002532; Chromosome.
DR   GO; GO:0005960; C:glycine cleavage complex; IEA:InterPro.
DR   GO; GO:0019464; P:glycine decarboxylation via glycine cleavage system; IEA:InterPro.
DR   CDD; cd06848; GCS_H; 1.
DR   InterPro; IPR003016; 2-oxoA_DH_lipoyl-BS.
DR   InterPro; IPR000089; Biotin_lipoyl.
DR   InterPro; IPR002930; GCV_H.
DR   InterPro; IPR033753; GCV_H/Fam206.
DR   InterPro; IPR017514; GcvH_Chlamydia.
DR   InterPro; IPR011053; Single_hybrid_motif.
DR   PANTHER; PTHR11715; PTHR11715; 1.
DR   Pfam; PF01597; GCV_H; 1.
DR   SUPFAM; SSF51230; SSF51230; 1.
DR   TIGRFAMs; TIGR03077; not_gcvH; 1.
DR   PROSITE; PS50968; BIOTINYL_LIPOYL; 1.
DR   PROSITE; PS00189; LIPOYL; 1.
PE   3: Inferred from homology;
KW   Lipoyl.
FT   CHAIN           1..117
FT                   /note="Glycine cleavage system H-like protein"
FT                   /id="PRO_0000302363"
FT   DOMAIN          21..103
FT                   /note="Lipoyl-binding"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01066"
FT   MOD_RES         62
FT                   /note="N6-lipoyllysine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01066"
SQ   SEQUENCE   117 AA;  13144 MW;  10D4D1B704280D0E CRC64;
     MKGKKYYSDY HVWIEPIHSR IVKLGLSSQM REHLGNILHI DLPSLGAFIK EGEKLCILES
     SKSAIEVLSP VSGEVLEVNT ALEDDILPVN NATESEGWFV VLQLTEDFRS ESFSLEP