ALLC_ACIBS
ID ALLC_ACIBS Reviewed; 336 AA.
AC B0VP26;
DT 14-APR-2009, integrated into UniProtKB/Swiss-Prot.
DT 08-APR-2008, sequence version 1.
DT 25-MAY-2022, entry version 81.
DE RecName: Full=Probable allantoicase {ECO:0000255|HAMAP-Rule:MF_00813};
DE EC=3.5.3.4 {ECO:0000255|HAMAP-Rule:MF_00813};
DE AltName: Full=Allantoate amidinohydrolase {ECO:0000255|HAMAP-Rule:MF_00813};
GN Name=alc {ECO:0000255|HAMAP-Rule:MF_00813}; OrderedLocusNames=ABSDF3499;
OS Acinetobacter baumannii (strain SDF).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Moraxellales; Moraxellaceae;
OC Acinetobacter; Acinetobacter calcoaceticus/baumannii complex.
OX NCBI_TaxID=509170;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SDF;
RX PubMed=18350144; DOI=10.1371/journal.pone.0001805;
RA Vallenet D., Nordmann P., Barbe V., Poirel L., Mangenot S., Bataille E.,
RA Dossat C., Gas S., Kreimeyer A., Lenoble P., Oztas S., Poulain J.,
RA Segurens B., Robert C., Abergel C., Claverie J.-M., Raoult D., Medigue C.,
RA Weissenbach J., Cruveiller S.;
RT "Comparative analysis of Acinetobacters: three genomes for three
RT lifestyles.";
RL PLoS ONE 3:E1805-E1805(2008).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=allantoate + H2O = (S)-ureidoglycolate + urea;
CC Xref=Rhea:RHEA:11016, ChEBI:CHEBI:15377, ChEBI:CHEBI:16199,
CC ChEBI:CHEBI:17536, ChEBI:CHEBI:57296; EC=3.5.3.4;
CC Evidence={ECO:0000255|HAMAP-Rule:MF_00813};
CC -!- PATHWAY: Nitrogen metabolism; (S)-allantoin degradation; (S)-
CC ureidoglycolate from allantoate (aminidohydrolase route): step 1/1.
CC {ECO:0000255|HAMAP-Rule:MF_00813}.
CC -!- SIMILARITY: Belongs to the allantoicase family. {ECO:0000255|HAMAP-
CC Rule:MF_00813}.
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DR EMBL; CU468230; CAP02762.1; -; Genomic_DNA.
DR AlphaFoldDB; B0VP26; -.
DR SMR; B0VP26; -.
DR EnsemblBacteria; CAP02762; CAP02762; ABSDF3499.
DR KEGG; abm:ABSDF3499; -.
DR HOGENOM; CLU_038797_1_2_6; -.
DR OMA; MDDGWET; -.
DR UniPathway; UPA00395; UER00654.
DR Proteomes; UP000001741; Chromosome.
DR GO; GO:0004037; F:allantoicase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0000256; P:allantoin catabolic process; IEA:UniProtKB-UniRule.
DR GO; GO:0006144; P:purine nucleobase metabolic process; IEA:UniProtKB-KW.
DR HAMAP; MF_00813; Allantoicase; 1.
DR InterPro; IPR005164; Allantoicase.
DR InterPro; IPR015908; Allantoicase_dom.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR PANTHER; PTHR12045; PTHR12045; 1.
DR Pfam; PF03561; Allantoicase; 2.
DR PIRSF; PIRSF016516; Allantoicase; 1.
DR SUPFAM; SSF49785; SSF49785; 2.
DR TIGRFAMs; TIGR02961; allantoicase; 1.
PE 3: Inferred from homology;
KW Hydrolase; Purine metabolism.
FT CHAIN 1..336
FT /note="Probable allantoicase"
FT /id="PRO_1000134087"
SQ SEQUENCE 336 AA; 37876 MW; BC12996E13E7506B CRC64;
MATLHAPAFE LPEILNTKTN LADARIGAQV IECSDDFFAE AKRMLQFEAP IFVEDKFDDH
GKWMDGWETR RKRHAGYDWC IVKLGVSGKI SALDIDTTFF TGNYPASASL EACYAPNSDL
TGAKWQSILE NTELGPSQHH IFMVNNDAIF THIRLNIFPD GGVARLRVYG DVHIQVTDHE
QTLDLLALEN GGRVIAYSDA HFGHPRNLIN PGRGVNMGDG WETKRRRAPG YDWCILALGK
SGKIEKIEID TAHFKGNFPA EVSIQAVYLE NATDAQLIPQ SMFWSYLLEA QPMQMDHIHE
YMNEILQHEK VSHIRINMIP DGGISRVRLW GKIAKS