ALLC_ACIBY
ID ALLC_ACIBY Reviewed; 336 AA.
AC B0V9T8;
DT 14-APR-2009, integrated into UniProtKB/Swiss-Prot.
DT 08-APR-2008, sequence version 1.
DT 25-MAY-2022, entry version 66.
DE RecName: Full=Probable allantoicase {ECO:0000255|HAMAP-Rule:MF_00813};
DE EC=3.5.3.4 {ECO:0000255|HAMAP-Rule:MF_00813};
DE AltName: Full=Allantoate amidinohydrolase {ECO:0000255|HAMAP-Rule:MF_00813};
GN Name=alc {ECO:0000255|HAMAP-Rule:MF_00813}; OrderedLocusNames=ABAYE0128;
OS Acinetobacter baumannii (strain AYE).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Moraxellales; Moraxellaceae;
OC Acinetobacter; Acinetobacter calcoaceticus/baumannii complex.
OX NCBI_TaxID=509173;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AYE;
RX PubMed=18350144; DOI=10.1371/journal.pone.0001805;
RA Vallenet D., Nordmann P., Barbe V., Poirel L., Mangenot S., Bataille E.,
RA Dossat C., Gas S., Kreimeyer A., Lenoble P., Oztas S., Poulain J.,
RA Segurens B., Robert C., Abergel C., Claverie J.-M., Raoult D., Medigue C.,
RA Weissenbach J., Cruveiller S.;
RT "Comparative analysis of Acinetobacters: three genomes for three
RT lifestyles.";
RL PLoS ONE 3:E1805-E1805(2008).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=allantoate + H2O = (S)-ureidoglycolate + urea;
CC Xref=Rhea:RHEA:11016, ChEBI:CHEBI:15377, ChEBI:CHEBI:16199,
CC ChEBI:CHEBI:17536, ChEBI:CHEBI:57296; EC=3.5.3.4;
CC Evidence={ECO:0000255|HAMAP-Rule:MF_00813};
CC -!- PATHWAY: Nitrogen metabolism; (S)-allantoin degradation; (S)-
CC ureidoglycolate from allantoate (aminidohydrolase route): step 1/1.
CC {ECO:0000255|HAMAP-Rule:MF_00813}.
CC -!- SIMILARITY: Belongs to the allantoicase family. {ECO:0000255|HAMAP-
CC Rule:MF_00813}.
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DR EMBL; CU459141; CAM85114.1; -; Genomic_DNA.
DR RefSeq; WP_000212411.1; NC_010410.1.
DR AlphaFoldDB; B0V9T8; -.
DR SMR; B0V9T8; -.
DR EnsemblBacteria; CAM85114; CAM85114; ABAYE0128.
DR KEGG; aby:ABAYE0128; -.
DR HOGENOM; CLU_038797_1_2_6; -.
DR OMA; MDDGWET; -.
DR UniPathway; UPA00395; UER00654.
DR Proteomes; UP000002446; Chromosome.
DR GO; GO:0004037; F:allantoicase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0000256; P:allantoin catabolic process; IEA:UniProtKB-UniRule.
DR GO; GO:0006144; P:purine nucleobase metabolic process; IEA:UniProtKB-KW.
DR HAMAP; MF_00813; Allantoicase; 1.
DR InterPro; IPR005164; Allantoicase.
DR InterPro; IPR015908; Allantoicase_dom.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR PANTHER; PTHR12045; PTHR12045; 1.
DR Pfam; PF03561; Allantoicase; 2.
DR PIRSF; PIRSF016516; Allantoicase; 1.
DR SUPFAM; SSF49785; SSF49785; 2.
DR TIGRFAMs; TIGR02961; allantoicase; 1.
PE 3: Inferred from homology;
KW Hydrolase; Purine metabolism.
FT CHAIN 1..336
FT /note="Probable allantoicase"
FT /id="PRO_1000134089"
SQ SEQUENCE 336 AA; 37829 MW; C8886594C7639244 CRC64;
MATLHAPAFE LPEILNTKTN LADARIGAQV IECSDDFFAE AKRMLQFEAP IFVEDKFDDH
GKWMDGWETR RKRHAGYDWC IVKLGVSGKI SALDIDTTFF TGNYPASASL EACYAPNGDL
TGVTWQSILE NTELGPSQHH IFMVNNDAIF THIRLNIFPD GGVARLRVYG DVHIQVTDHE
QTLDLLALEN GGRVIAYSDA HFGHPRNLIN PGRGVNMGDG WETKRRRAPG YDWCILALGK
SGKIEKIEID TAHFKGNFPA EVSIQAVYLE NATDAQLIPQ SMFWSYLLEA QPMQMDHIHE
YVNEILKHEK ISHIRINMIP DGGISRVRLW GKIAKS