ID   ALLC_AGRIP              Reviewed;          38 AA.
AC   C0HKS0;
DT   20-JUN-2018, integrated into UniProtKB/Swiss-Prot.
DT   20-JUN-2018, sequence version 1.
DT   25-MAY-2022, entry version 7.
DE   RecName: Full=Allatostatin-C {ECO:0000303|PubMed:29466015};
DE   Flags: Precursor;
OS   Agrotis ipsilon (Black cutworm moth).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Noctuoidea;
OC   Noctuidae; Noctuinae; Noctuini; Agrotis.
OX   NCBI_TaxID=56364;
RN   [1] {ECO:0000305}
RP   NUCLEOTIDE SEQUENCE [MRNA], PROTEIN SEQUENCE OF 22-36, TISSUE SPECIFICITY,
RP   MASS SPECTROMETRY, IDENTIFICATION BY MASS SPECTROMETRY, AND PYROGLUTAMATE
RP   FORMATION AT GLN-22.
RX   PubMed=29466015; DOI=10.1021/acs.jproteome.7b00779;
RA   Diesner M., Gallot A., Binz H., Gaertner C., Vitecek S., Kahnt J.,
RA   Schachtner J., Jacquin-Joly E., Gadenne C.;
RT   "Mating-induced differential peptidomics of neuropeptides and protein
RT   hormones in Agrotis ipsilon moths.";
RL   J. Proteome Res. 17:1397-1414(2018).
CC   -!- FUNCTION: Strongly inhibits juvenile hormone biosynthesis.
CC       {ECO:0000250|UniProtKB:P42559}.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305}.
CC   -!- TISSUE SPECIFICITY: In its non-pyroglutamate form, expressed in
CC       antennal lobe (AL), corpora cardiaca (CC), corpora allata (CA) and
CC       gnathal ganglion (GNG) with expression in AL detected in most animals
CC       and expression in CC, CA and GNG detected in few animals (at protein
CC       level). In its pyroglutamate form, expressed in antennal lobe (AL),
CC       corpora cardiaca (CC) and corpora allata (CA) with expression detected
CC       in few animals (at protein level). Not expressed in GNG (protein
CC       level). {ECO:0000269|PubMed:29466015}.
CC   -!- MASS SPECTROMETRY: Mass=1905.89; Method=MALDI; Note=Non-pyroglutamate
CC       form.; Evidence={ECO:0000269|PubMed:29466015};
CC   -!- MASS SPECTROMETRY: Mass=1888.89; Method=MALDI; Note=Pyroglutamate
CC       form.; Evidence={ECO:0000269|PubMed:29466015};
CC   -!- SIMILARITY: Belongs to the allatostatin family. {ECO:0000305}.
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DR   AlphaFoldDB; C0HKS0; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0007218; P:neuropeptide signaling pathway; IEA:UniProtKB-KW.
PE   1: Evidence at protein level;
KW   Cleavage on pair of basic residues; Direct protein sequencing;
KW   Neuropeptide; Pyrrolidone carboxylic acid; Secreted.
FT   PROPEP          1..19
FT                   /evidence="ECO:0000305"
FT                   /id="PRO_0000444515"
FT   PEPTIDE         22..36
FT                   /note="Allatostatin-C"
FT                   /evidence="ECO:0000269|PubMed:29466015"
FT                   /id="PRO_0000444516"
FT   MOD_RES         22
FT                   /note="Pyrrolidone carboxylic acid; partial"
FT                   /evidence="ECO:0000269|PubMed:29466015"
SQ   SEQUENCE   38 AA;  4492 MW;  BBB6E8DCC507FF65 CRC64;
     MRRALDGPGS SSLDTRQADK RQVRFRQCYF NPISCFRK