位置:首页 > 蛋白库 > ALLC_MOUSE
ALLC_MOUSE
ID   ALLC_MOUSE              Reviewed;         414 AA.
AC   Q9JHX6; E9QL21;
DT   13-SEP-2005, integrated into UniProtKB/Swiss-Prot.
DT   28-JUN-2011, sequence version 2.
DT   03-AUG-2022, entry version 118.
DE   RecName: Full=Probable inactive allantoicase;
DE   AltName: Full=Allantoate amidinohydrolase;
GN   Name=Allc {ECO:0000312|MGI:MGI:2136971};
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Mus; Mus.
OX   NCBI_TaxID=10090;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   STRAIN=CD-1;
RX   PubMed=11406280; DOI=10.1016/s0167-4781(01)00207-x;
RA   Vigetti D., Monetti C., Bernardini G.;
RT   "Molecular cloning of mouse allantoicase cDNA.";
RL   Biochim. Biophys. Acta 1519:117-121(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=C57BL/6J;
RX   PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA   Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA   Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA   Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA   Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA   Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA   Eichler E.E., Ponting C.P.;
RT   "Lineage-specific biology revealed by a finished genome assembly of the
RT   mouse.";
RL   PLoS Biol. 7:E1000112-E1000112(2009).
RN   [3]
RP   GENE STRUCTURE, AND FUNCTION.
RX   PubMed=12036579; DOI=10.1016/s0378-1119(02)00541-3;
RA   Vigetti D., Monetti C., Prati M., Gornati R., Bernardini G.;
RT   "Genomic organization and chromosome localization of the murine and human
RT   allantoicase gene.";
RL   Gene 289:13-17(2002).
RN   [4]
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC   TISSUE=Testis;
RX   PubMed=21183079; DOI=10.1016/j.cell.2010.12.001;
RA   Huttlin E.L., Jedrychowski M.P., Elias J.E., Goswami T., Rad R.,
RA   Beausoleil S.A., Villen J., Haas W., Sowa M.E., Gygi S.P.;
RT   "A tissue-specific atlas of mouse protein phosphorylation and expression.";
RL   Cell 143:1174-1189(2010).
CC   -!- FUNCTION: The function of this enzyme is unclear as allantoicase
CC       activity is not known to exist in mammals.
CC       {ECO:0000305|PubMed:12036579}.
CC   -!- SIMILARITY: Belongs to the allantoicase family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AF278712; AAF86348.1; -; mRNA.
DR   EMBL; AC165283; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   CCDS; CCDS25850.1; -.
DR   RefSeq; NP_444386.2; NM_053156.2.
DR   RefSeq; XP_006515350.1; XM_006515287.1.
DR   AlphaFoldDB; Q9JHX6; -.
DR   SMR; Q9JHX6; -.
DR   STRING; 10090.ENSMUSP00000020965; -.
DR   PhosphoSitePlus; Q9JHX6; -.
DR   REPRODUCTION-2DPAGE; Q9JHX6; -.
DR   PaxDb; Q9JHX6; -.
DR   PRIDE; Q9JHX6; -.
DR   ProteomicsDB; 296173; -.
DR   Antibodypedia; 26390; 94 antibodies from 21 providers.
DR   DNASU; 94041; -.
DR   Ensembl; ENSMUST00000020965; ENSMUSP00000020965; ENSMUSG00000020636.
DR   Ensembl; ENSMUST00000110917; ENSMUSP00000106542; ENSMUSG00000020636.
DR   GeneID; 94041; -.
DR   KEGG; mmu:94041; -.
DR   UCSC; uc007nfp.3; mouse.
DR   CTD; 55821; -.
DR   MGI; MGI:2136971; Allc.
DR   VEuPathDB; HostDB:ENSMUSG00000020636; -.
DR   eggNOG; KOG4145; Eukaryota.
DR   GeneTree; ENSGT00390000001793; -.
DR   HOGENOM; CLU_038797_1_2_1; -.
DR   InParanoid; Q9JHX6; -.
DR   OMA; MDDGWET; -.
DR   OrthoDB; 563639at2759; -.
DR   PhylomeDB; Q9JHX6; -.
DR   TreeFam; TF324677; -.
DR   BRENDA; 3.5.3.4; 3474.
DR   BioGRID-ORCS; 94041; 3 hits in 72 CRISPR screens.
DR   PRO; PR:Q9JHX6; -.
DR   Proteomes; UP000000589; Chromosome 12.
DR   RNAct; Q9JHX6; protein.
DR   Bgee; ENSMUSG00000020636; Expressed in spermatid and 30 other tissues.
DR   Genevisible; Q9JHX6; MM.
DR   GO; GO:0004037; F:allantoicase activity; IEA:UniProtKB-EC.
DR   GO; GO:0000256; P:allantoin catabolic process; IEA:InterPro.
DR   HAMAP; MF_00813; Allantoicase; 1.
DR   InterPro; IPR005164; Allantoicase.
DR   InterPro; IPR015908; Allantoicase_dom.
DR   InterPro; IPR008979; Galactose-bd-like_sf.
DR   PANTHER; PTHR12045; PTHR12045; 1.
DR   Pfam; PF03561; Allantoicase; 2.
DR   PIRSF; PIRSF016516; Allantoicase; 1.
DR   SUPFAM; SSF49785; SSF49785; 2.
DR   TIGRFAMs; TIGR02961; allantoicase; 1.
PE   1: Evidence at protein level;
KW   Reference proteome.
FT   CHAIN           1..414
FT                   /note="Probable inactive allantoicase"
FT                   /id="PRO_0000205907"
FT   CONFLICT        2
FT                   /note="T -> A (in Ref. 1; AAF86348)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        211
FT                   /note="D -> G (in Ref. 1; AAF86348)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   414 AA;  46294 MW;  A7BD1FDB443AE177 CRC64;
     MTDTPKEGKL TRFLDFTQLI DLASECVGGK VLFATDDFFG PAENLIKSDS PTFKEHEYTE
     FGKWVDGWET RRKRIPGHDW CVIQLGIQGI IRGIDVDISY FSGNHAPRMS IQAANLSEED
     TMSNIPPRGV RMGTAATPEE FEAVTELKSH SWDYLVPMSE LKLGDPDSSH NYYFVNSQQR
     WTHIRLNIFP DGGVARLRVY GTGQRDWAAL DSTEPVDLVA IAFGGVCVGF SNAHFGHPNN
     MIGVGEPKSI ADGWETARRL DRPPVLEASE NGLLLVPGCE WAVFRLAHPG VITQIEIDTK
     YFKGNCPNSC KVDGCILTTL EEEDMIRHNW NLPAHKWKSL LPVTKLIPNQ NHLLDSLTLE
     LQDVITHAMI TIAPDGGVSR LRLKGFPSSI CLLRPLREKP LLRFSLKTGF RANL
 
 
维奥蛋白资源库 - 中文蛋白资源 CopyRight © 2010-2024