ID   ALLC_NOCFA              Reviewed;         329 AA.
AC   Q5YP02;
DT   13-SEP-2005, integrated into UniProtKB/Swiss-Prot.
DT   23-NOV-2004, sequence version 1.
DT   03-AUG-2022, entry version 99.
DE   RecName: Full=Probable allantoicase {ECO:0000255|HAMAP-Rule:MF_00813};
DE            EC=3.5.3.4 {ECO:0000255|HAMAP-Rule:MF_00813};
DE   AltName: Full=Allantoate amidinohydrolase {ECO:0000255|HAMAP-Rule:MF_00813};
GN   Name=alc {ECO:0000255|HAMAP-Rule:MF_00813}; OrderedLocusNames=NFA_52370;
OS   Nocardia farcinica (strain IFM 10152).
OC   Bacteria; Actinobacteria; Corynebacteriales; Nocardiaceae; Nocardia.
OX   NCBI_TaxID=247156;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=IFM 10152;
RX   PubMed=15466710; DOI=10.1073/pnas.0406410101;
RA   Ishikawa J., Yamashita A., Mikami Y., Hoshino Y., Kurita H., Hotta K.,
RA   Shiba T., Hattori M.;
RT   "The complete genomic sequence of Nocardia farcinica IFM 10152.";
RL   Proc. Natl. Acad. Sci. U.S.A. 101:14925-14930(2004).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=allantoate + H2O = (S)-ureidoglycolate + urea;
CC         Xref=Rhea:RHEA:11016, ChEBI:CHEBI:15377, ChEBI:CHEBI:16199,
CC         ChEBI:CHEBI:17536, ChEBI:CHEBI:57296; EC=3.5.3.4;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_00813};
CC   -!- PATHWAY: Nitrogen metabolism; (S)-allantoin degradation; (S)-
CC       ureidoglycolate from allantoate (aminidohydrolase route): step 1/1.
CC       {ECO:0000255|HAMAP-Rule:MF_00813}.
CC   -!- SIMILARITY: Belongs to the allantoicase family. {ECO:0000255|HAMAP-
CC       Rule:MF_00813}.
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DR   EMBL; AP006618; BAD60089.1; -; Genomic_DNA.
DR   RefSeq; WP_011211771.1; NC_006361.1.
DR   AlphaFoldDB; Q5YP02; -.
DR   SMR; Q5YP02; -.
DR   STRING; 247156.NFA_52370; -.
DR   EnsemblBacteria; BAD60089; BAD60089; NFA_52370.
DR   GeneID; 61135814; -.
DR   KEGG; nfa:NFA_52370; -.
DR   eggNOG; COG4266; Bacteria.
DR   HOGENOM; CLU_038797_1_0_11; -.
DR   OMA; WTHIRIN; -.
DR   BioCyc; NFAR247156:NFA_RS25980-MON; -.
DR   UniPathway; UPA00395; UER00654.
DR   Proteomes; UP000006820; Chromosome.
DR   GO; GO:0004037; F:allantoicase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0000256; P:allantoin catabolic process; IEA:UniProtKB-UniRule.
DR   GO; GO:0006144; P:purine nucleobase metabolic process; IEA:UniProtKB-KW.
DR   HAMAP; MF_00813; Allantoicase; 1.
DR   InterPro; IPR005164; Allantoicase.
DR   InterPro; IPR015908; Allantoicase_dom.
DR   InterPro; IPR008979; Galactose-bd-like_sf.
DR   PANTHER; PTHR12045; PTHR12045; 1.
DR   Pfam; PF03561; Allantoicase; 2.
DR   PIRSF; PIRSF016516; Allantoicase; 1.
DR   SUPFAM; SSF49785; SSF49785; 2.
DR   TIGRFAMs; TIGR02961; allantoicase; 1.
PE   3: Inferred from homology;
KW   Hydrolase; Purine metabolism; Reference proteome.
FT   CHAIN           1..329
FT                   /note="Probable allantoicase"
FT                   /id="PRO_0000205921"
SQ   SEQUENCE   329 AA;  35822 MW;  3CD6293A987FEF7F CRC64;
     MNETAADRVA PRGFTELPDL AVRSLGGAVI WADDEFFAEK ENLIVPEAPE FRPATYGHRG
     QVYDGWETRR HRGLPGDDAA VVRLGVPGVI HGVVVDTSWF TGNYPPAISL SALAIDGYPP
     AADIAARTDW VPLLDRVPVR GDARNPFPIP SRDRWTHVRL TMHPDGGIAR LRVHGEGRPD
     PALLGLGPVD LAALENGALV LDCSDRFYGS PHQLLHPGNA RRMGDGWETA RRRDDGNDWV
     RIRLAGPGLI RLAELDTSYF LGNSPAAARL TGRTTDGTEV ELLPRTPLQP DTRHRFPTAA
     VAASVEEVRL DIYPDGGLAR VRLFGELGG