ID   ALLC_PHOPR              Reviewed;         330 AA.
AC   Q6LPX9;
DT   13-SEP-2005, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   25-MAY-2022, entry version 95.
DE   RecName: Full=Probable allantoicase {ECO:0000255|HAMAP-Rule:MF_00813};
DE            EC=3.5.3.4 {ECO:0000255|HAMAP-Rule:MF_00813};
DE   AltName: Full=Allantoate amidinohydrolase {ECO:0000255|HAMAP-Rule:MF_00813};
GN   Name=alc {ECO:0000255|HAMAP-Rule:MF_00813}; OrderedLocusNames=PBPRA2261;
OS   Photobacterium profundum (strain SS9).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC   Photobacterium.
OX   NCBI_TaxID=298386;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-1253 / SS9;
RX   PubMed=15746425; DOI=10.1126/science.1103341;
RA   Vezzi A., Campanaro S., D'Angelo M., Simonato F., Vitulo N., Lauro F.M.,
RA   Cestaro A., Malacrida G., Simionati B., Cannata N., Romualdi C.,
RA   Bartlett D.H., Valle G.;
RT   "Life at depth: Photobacterium profundum genome sequence and expression
RT   analysis.";
RL   Science 307:1459-1461(2005).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=allantoate + H2O = (S)-ureidoglycolate + urea;
CC         Xref=Rhea:RHEA:11016, ChEBI:CHEBI:15377, ChEBI:CHEBI:16199,
CC         ChEBI:CHEBI:17536, ChEBI:CHEBI:57296; EC=3.5.3.4;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_00813};
CC   -!- PATHWAY: Nitrogen metabolism; (S)-allantoin degradation; (S)-
CC       ureidoglycolate from allantoate (aminidohydrolase route): step 1/1.
CC       {ECO:0000255|HAMAP-Rule:MF_00813}.
CC   -!- SIMILARITY: Belongs to the allantoicase family. {ECO:0000255|HAMAP-
CC       Rule:MF_00813}.
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DR   EMBL; CR378670; CAG20647.1; -; Genomic_DNA.
DR   RefSeq; WP_011218937.1; NC_006370.1.
DR   AlphaFoldDB; Q6LPX9; -.
DR   SMR; Q6LPX9; -.
DR   STRING; 298386.PBPRA2261; -.
DR   PRIDE; Q6LPX9; -.
DR   EnsemblBacteria; CAG20647; CAG20647; PBPRA2261.
DR   KEGG; ppr:PBPRA2261; -.
DR   eggNOG; COG4266; Bacteria.
DR   HOGENOM; CLU_038797_1_2_6; -.
DR   OMA; MDDGWET; -.
DR   OrthoDB; 651058at2; -.
DR   UniPathway; UPA00395; UER00654.
DR   Proteomes; UP000000593; Chromosome 1.
DR   GO; GO:0004037; F:allantoicase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0000256; P:allantoin catabolic process; IEA:UniProtKB-UniRule.
DR   GO; GO:0006144; P:purine nucleobase metabolic process; IEA:UniProtKB-KW.
DR   HAMAP; MF_00813; Allantoicase; 1.
DR   InterPro; IPR005164; Allantoicase.
DR   InterPro; IPR015908; Allantoicase_dom.
DR   InterPro; IPR008979; Galactose-bd-like_sf.
DR   PANTHER; PTHR12045; PTHR12045; 1.
DR   Pfam; PF03561; Allantoicase; 2.
DR   PIRSF; PIRSF016516; Allantoicase; 1.
DR   SUPFAM; SSF49785; SSF49785; 2.
DR   TIGRFAMs; TIGR02961; allantoicase; 1.
PE   3: Inferred from homology;
KW   Hydrolase; Purine metabolism; Reference proteome.
FT   CHAIN           1..330
FT                   /note="Probable allantoicase"
FT                   /id="PRO_0000205922"
SQ   SEQUENCE   330 AA;  36577 MW;  E8A8F4E9BAD5E6E5 CRC64;
     MEKALNFEQY VNLADPKLGA EAIFATDDFF ADKSRLIRTE AAEWKEDLYD DNGKWMDGWE
     SRRKRSEGYD FCVVRLGLAG TIAGLDIDTS FFTGNFPPSA SVDACYSPDG EPSDSTEWQE
     ILSSQSLQGD SHHLHALDNE QVFTHVRLNI YPDGGVARLR VYGRPSVNWD QIGIDQEVDL
     AAVVNGGRAL ACSDEHFGKK SNILGPGRGE NMGDGWETAR RRTPGNDWVI VALGRPGKIG
     KVVVDTAHFK GNFPDSCSIQ AAYVQGGTDD QVETQSLFWR ELMPSQKLSA HNIQEFVEQV
     NDLGAVTHVR LNIFPDGGIS RLRLFGFKSE